Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer
about
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerasesEukaryotic translesion polymerases and their roles and regulation in DNA damage toleranceStructural basis of error-prone replication and stalling at a thymine base by human DNA polymerase ιY-Family Polymerase Conformation Is a Major Determinant of Fidelity and Translesion SpecificityThe mechanisms of UV mutagenesis.DNA polymerase eta participates in the mutagenic bypass of adducts induced by benzo[a]pyrene diol epoxide in mammalian cellsEvidence of ultraviolet type mutations in xeroderma pigmentosum melanomas.Influence of local sequence context on damaged base conformation in human DNA polymerase iota: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesionREV1 is implicated in the development of carcinogen-induced lung cancer.Error-prone translesion replication of damaged DNA suppresses skin carcinogenesis by controlling inflammatory hyperplasiaA founder large deletion mutation in Xeroderma pigmentosum-Variant form in Tunisia: implication for molecular diagnosis and therapyEffect of rapid human N-acetyltransferase 2 haplotype on DNA damage and mutagenesis induced by 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ) and 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline (MeIQx).Inaccurate DNA synthesis in cell extracts of yeast producing active human DNA polymerase iota.Redundancy of mammalian Y family DNA polymerases in cellular responses to genomic DNA lesions induced by ultraviolet lightTranslesion DNA polymerasesBiochemical analysis of six genetic variants of error-prone human DNA polymerase ι involved in translesion DNA synthesis.Kinetic approaches to understanding the mechanisms of fidelity of the herpes simplex virus type 1 DNA polymeraseIncreased catalytic activity and altered fidelity of human DNA polymerase iota in the presence of manganese.Mutator phenotypes due to DNA replication infidelity.Dysregulation of DNA polymerase κ recruitment to replication forks results in genomic instability.129-Derived Mouse Strains Express an Unstable but Catalytically Active DNA Polymerase Iota VariantWhat a difference a decade makes: insights into translesion DNA synthesis.PCNA modifications for regulation of post-replication repair pathwaysInhibition of DNA replication fork progression and mutagenic potential of 1, N6-ethenoadenine and 8-oxoguanine in human cell extracts.Multiple functions of DNA polymerases.Evolving views of DNA replication (in)fidelity.Xeroderma pigmentosum-variant patients from America, Europe, and Asia.DNA polymerases and cancer.DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients.Somatic microindels in human cancer: the insertions are highly error-prone and derive from nearby but not adjacent sense and antisense templates.Competitive repair pathways in immunoglobulin gene hypermutation.Lack of DNA polymerase theta (POLQ) radiosensitizes bone marrow stromal cells in vitro and increases reticulocyte micronuclei after total-body irradiation.Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools.Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.Mouse models of DNA polymerases.The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability.Translesion DNA synthesis and mutagenesis in eukaryotesThe error-prone DNA polymerase ι provides quantitative resistance to lung tumorigenesis and mutagenesis in mice.Mouse DNA polymerase ι lacking the forty-two amino acids encoded by exon-2 is catalytically inactive in vitro.Human DNA polymerase eta is required for common fragile site stability during unperturbed DNA replication
P2860
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P2860
Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer
description
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2006
@ast
im November 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/11/28)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/11/28)
@nl
наукова стаття, опублікована в листопаді 2006
@uk
name
Participation of mouse DNA pol ...... and suppression of skin cancer
@ast
Participation of mouse DNA pol ...... and suppression of skin cancer
@en
Participation of mouse DNA pol ...... and suppression of skin cancer
@nl
type
label
Participation of mouse DNA pol ...... and suppression of skin cancer
@ast
Participation of mouse DNA pol ...... and suppression of skin cancer
@en
Participation of mouse DNA pol ...... and suppression of skin cancer
@nl
prefLabel
Participation of mouse DNA pol ...... and suppression of skin cancer
@ast
Participation of mouse DNA pol ...... and suppression of skin cancer
@en
Participation of mouse DNA pol ...... and suppression of skin cancer
@nl
P2093
P2860
P921
P356
P1476
Participation of mouse DNA pol ...... and suppression of skin cancer
@en
P2093
Alan B Clark
Chad A Dumstorf
Grace E Kissling
Qingcong Lin
Raju Kucherlapati
W Glenn McGregor
P2860
P304
18083-18088
P356
10.1073/PNAS.0605247103
P407
P577
2006-11-17T00:00:00Z