Characterization of otoconin-95, the major protein of murine otoconia, provides insights into the formation of these inner ear biominerals
about
Novel human secreted phospholipase A(2) with homology to the group III bee venom enzymeOTOF encodes multiple long and short isoforms: genetic evidence that the long ones underlie recessive deafness DFNB9.Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionMammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1Otoancorin, an inner ear protein restricted to the interface between the apical surface of sensory epithelia and their overlying acellular gels, is defective in autosomal recessive deafness DFNB22.Vestibular dysgenesis in mice lacking Abr and Bcr Cdc42/RacGAPsFdp, a new fibrocyte-derived protein related to MIA/CD-RAP, has an in vitro effect on the early differentiation of the inner ear mesenchymeTargeted disruption of otog results in deafness and severe imbalanceOn the diversity of secreted phospholipases A(2). Cloning, tissue distribution, and functional expression of two novel mouse group II enzymesExtracellular matrices associated with the apical surfaces of sensory epithelia in the inner ear: Molecular and structural diversityGene targeting reveals the role of Oc90 as the essential organizer of the otoconial organic matrixThe biomedical discourse relation bankOsteopontin is not critical for otoconia formation or balance function.Otoconin-90 deletion leads to imbalance but normal hearing: a comparison with other otoconia mutantsInner ear hair cell-like cells from human embryonic stem cells.Reconstruction of the mouse otocyst and early neuroblast lineage at single-cell resolution.3D computational reconstruction of tissues with hollow spherical morphologies using single-cell gene expression data.Proteomic analysis of S-nitrosylated proteins in mesangial cells.Matrix recruitment and calcium sequestration for spatial specific otoconia developmentCalcium oxalate stone formation in the inner ear as a result of an Slc26a4 mutation.Cell type-specific transcriptome analysis reveals a major role for Zeb1 and miR-200b in mouse inner ear morphogenesis.In vitro effects of recombinant otoconin 90 upon calcite crystal growth. Significance of tertiary structureRegulation of cellular calcium in vestibular supporting cells by otopetrin 1Expression, functional, and structural analysis of proteins critical for otoconia developmentUnderstanding inner ear development with gene expression profiling.Effect of Otoconial Proteins Fetuin A, Osteopontin, and Otoconin 90 on the Nucleation and Growth of Calcite.Applications of genomics in the inner ear.Mechanisms of otoconia and otolith developmentToward a systems biology of mouse inner ear organogenesis: gene expression pathways, patterns and network analysis.Mixing model systems: using zebrafish and mouse inner ear mutants and other organ systems to unravel the mystery of otoconial developmentDevelopment and evolution of the vestibular sensory apparatus of the mammalian ear.Immunogold TEM of otoconin 90 and otolin - relevance to mineralization of otoconia, and pathogenesis of benign positional vertigo.Sparc protein is required for normal growth of zebrafish otoliths.Otoc1: a novel otoconin-90 ortholog required for otolith mineralization in zebrafish.Spatiotemporal differences in otoconial gene expression.Formation of the inner ear during embryonic and larval development of the cichlid fish (Oreochromis mossambicus).Training and aging modulate the loss-of-balance phenotype observed in a new ENU-induced allele of Otopetrin1.Identification and characterization of mouse otic sensory lineage genes.Immunocytochemical localization of secretory phospholipase A(2)-like protein in the pituitary gland and surrounding tissue of the bullfrog, Rana catesbeiana.Developmental expression of otoconin-22 in the bullfrog endolymphatic sac and inner ear.
P2860
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P2860
Characterization of otoconin-95, the major protein of murine otoconia, provides insights into the formation of these inner ear biominerals
description
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1999
@ast
im Januar 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/01/19)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/01/19)
@nl
наукова стаття, опублікована в січні 1999
@uk
name
Characterization of otoconin-9 ...... of these inner ear biominerals
@ast
Characterization of otoconin-9 ...... of these inner ear biominerals
@en
Characterization of otoconin-9 ...... of these inner ear biominerals
@nl
type
label
Characterization of otoconin-9 ...... of these inner ear biominerals
@ast
Characterization of otoconin-9 ...... of these inner ear biominerals
@en
Characterization of otoconin-9 ...... of these inner ear biominerals
@nl
prefLabel
Characterization of otoconin-9 ...... of these inner ear biominerals
@ast
Characterization of otoconin-9 ...... of these inner ear biominerals
@en
Characterization of otoconin-9 ...... of these inner ear biominerals
@nl
P2860
P356
P1476
Characterization of otoconin-9 ...... of these inner ear biominerals
@en
P2093
M. Leibovici
P2860
P304
P356
10.1073/PNAS.96.2.529
P407
P577
1999-01-19T00:00:00Z