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Crystal structure of inhibitor-bound human 5-lipoxygenase-activating proteinA Covalent Linker Allows for Membrane Targeting of an Oxylipin Biosynthetic Complex † ‡The nuclear membrane organization of leukotriene synthesis12R-lipoxygenase deficiency disrupts epidermal barrier functionFLAP pharmacological blockade modulates metabolism of endogenous tau in vivo .Location, location, location: compartmentalization of early events in leukotriene biosynthesis.CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cells.Leukotriene A4 hydrolase/aminopeptidase, the gatekeeper of chemotactic leukotriene B4 biosynthesis.Cytosolic phospholipase A₂: physiological function and role in disease.Ly6G ligation blocks recruitment of neutrophils via a β2-integrin-dependent mechanismInvolvement of 5-lipoxygenase activating protein in the amyloidotic phenotype of an Alzheimer's disease mouse modelStructure and ligand based drug design strategies in the development of novel 5- LOX inhibitors.The nuclear membrane leukotriene synthetic complex is a signal integrator and transducer.5-Lipoxygenase-activating protein rescues activity of 5-lipoxygenase mutations that delay nuclear membrane association and disrupt product formation5-Lipoxygenase: mechanisms of regulation.Identifying intracellular sites of eicosanoid lipid mediator synthesis with EicosaCell assays.The Lipoxygenases: Their Regulation and Implication in Alzheimer's Disease.2-Arylbenzo[b]furan derivatives as potent human lipoxygenase inhibitors.An essential role of NAD(P)H oxidase 2 in UVA-induced calcium oscillations in mast cells.5-Lipoxygenase-activating protein homodimer in human neutrophils: evidence for a role in leukotriene biosynthesis.Britanin Suppresses IgE/Ag-Induced Mast Cell Activation by Inhibiting the Syk Pathway.EicosaCell - an immunofluorescent-based assay to localize newly synthesized eicosanoid lipid mediators at intracellular sites.Pharmacodynamics and pharmacokinetics of AM103, a novel inhibitor of 5-lipoxygenase-activating protein (FLAP).CarbORev-5901: The First Carborane-Based Inhibitor of the 5-Lipoxygenase Pathway.Effect of arachidonic acid reacylation on leukotriene biosynthesis in human neutrophils stimulated with granulocyte-macrophage colony-stimulating factor and formyl-methionyl-leucyl-phenylalanine.EicosaCell: An Imaging-Based Assay to Identify Spatiotemporal Eicosanoid Synthesis.Lipid droplets in host–pathogen interactions
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description
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2004
@ast
im April 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/04/27)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/04/27)
@nl
наукова стаття, опублікована у квітні 2004
@uk
name
The membrane organization of leukotriene synthesis
@ast
The membrane organization of leukotriene synthesis
@en
The membrane organization of leukotriene synthesis
@nl
type
label
The membrane organization of leukotriene synthesis
@ast
The membrane organization of leukotriene synthesis
@en
The membrane organization of leukotriene synthesis
@nl
prefLabel
The membrane organization of leukotriene synthesis
@ast
The membrane organization of leukotriene synthesis
@en
The membrane organization of leukotriene synthesis
@nl
P2093
P2860
P356
P1476
The membrane organization of leukotriene synthesis
@en
P2093
Asim K. Mandal
Brian J. Bacskai
Douglas Miller
Douglas Wisniewski
Jesse Skoch
Jilly F. Evans
Peter Christmas
Roy J. Soberman
Ting-ting D. Yamin
P2860
P304
P356
10.1073/PNAS.0308523101
P407
P577
2004-04-27T00:00:00Z