Novel role of the membrane-bound chemokine fractalkine in platelet activation and adhesion
about
Integrins αvβ3 and α4β1 act as coreceptors for fractalkine, and the integrin-binding defective mutant of fractalkine is an antagonist of CX3CR1The cannabinoid receptor-1 antagonist rimonabant inhibits platelet activation and reduces pro-inflammatory chemokines and leukocytes in Zucker ratsLeukocyte migration and graft-versus-host disease.The chemokine fractalkine can activate integrins without CX3CR1 through direct binding to a ligand-binding site distinct from the classical RGD-binding site.Chemokine receptor CX3CR1 regulates renal interstitial fibrosis after ischemia-reperfusion injury.Shear stress-induced changes in atherosclerotic plaque composition are modulated by chemokines.Cell-specific processing and release of the hormone-like precursor and candidate tumor suppressor gene product, Ecrg4Novel uses for anti-platelet agents as anti-inflammatory drugs.Chemokines: inflammatory mediators of atherosclerosis.Platelet chemokines in vascular disease.The NF-κB specific inhibitor DHMEQ prevents thrombus formation in a mouse model of antiphospholipid syndrome.Therapeutic implications of chemokine-mediated pathways in atherosclerosis: realistic perspectives and utopias.Chemokines and atherosclerosis: focus on the CX3CL1/CX3CR1 pathway.Platelets in leucocyte recruitment and function.Modulation of platelet and monocyte function by the chemokine fractalkine (CX3 CL1) in cardiovascular disease.Chebulagic acid inhibits the LPS-induced expression of TNF-α and IL-1β in endothelial cells by suppressing MAPK activation.SDF-1α is a novel autocrine activator of platelets operating through its receptor CXCR4.Fractalkine/CX3CL1 production by human airway smooth muscle cells: induction by IFN-gamma and TNF-alpha and regulation by TGF-beta and corticosteroids.The chemokine receptor CX3CR1 coordinates monocyte recruitment and endothelial regeneration after arterial injury.Elevated fractalkine in patients with obstructive sleep apnea hypopnea syndrome.Downregulation of CX3CR1 ameliorates experimental colitis: evidence for CX3CL1-CX3CR1-mediated immune cell recruitment.CX3CL1/CX3CR1 axis, as The Therapeutic Potential In Renal Diseases: Friend Or Foe?
P2860
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P2860
Novel role of the membrane-bound chemokine fractalkine in platelet activation and adhesion
description
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Januar 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/01/15)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/01/15)
@nl
наукова стаття, опублікована в січні 2004
@uk
مقالة علمية (نشرت في 15-1-2004)
@ar
name
Novel role of the membrane-bou ...... atelet activation and adhesion
@ast
Novel role of the membrane-bou ...... atelet activation and adhesion
@en
Novel role of the membrane-bou ...... atelet activation and adhesion
@nl
type
label
Novel role of the membrane-bou ...... atelet activation and adhesion
@ast
Novel role of the membrane-bou ...... atelet activation and adhesion
@en
Novel role of the membrane-bou ...... atelet activation and adhesion
@nl
prefLabel
Novel role of the membrane-bou ...... atelet activation and adhesion
@ast
Novel role of the membrane-bou ...... atelet activation and adhesion
@en
Novel role of the membrane-bou ...... atelet activation and adhesion
@nl
P2093
P1433
P1476
Novel role of the membrane-bou ...... atelet activation and adhesion
@en
P2093
Andreas Schäfer
Anna Kobsar
Christian Schulz
Daniela Fraccarollo
Georg Ertl
Johann Bauersachs
Martin Eigenthaler
Meinrad Gawaz
Ulrich Walter
P304
P356
10.1182/BLOOD-2002-10-3260
P407
P577
2004-01-15T00:00:00Z