Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer
about
Next generation sequencing with copy number variant detection expands the phenotypic spectrum of HSD17B4-deficiency.Differential expression of liver and kidney proteins in a mouse model for primary hyperoxaluria type I.An animal model of type A cystinuria due to spontaneous mutation in 129S2/SvPasCrl mice.Glyoxylate rather than ascorbate is an efficient precursor for oxalate biosynthesis in rice.Pharmacologic rescue of an enzyme-trafficking defect in primary hyperoxaluria 1.Enteric oxalate elimination is induced and oxalate is normalized in a mouse model of primary hyperoxaluria following intestinal colonization with OxalobacterPhenotypic correction of a mouse model for primary hyperoxaluria with adeno-associated virus gene transfer.Hydroxyproline metabolism in mouse models of primary hyperoxaluria.Natural Genetic Variation Influences Protein Abundances in C. elegans Developmental Signalling Pathways.Bifidobacterium animalis subsp. lactis decreases urinary oxalate excretion in a mouse model of primary hyperoxaluriaGenetic basis of renal cellular dysfunction and the formation of kidney stones.Calcium oxalate crystal deposition in kidneys of hypercalciuric mice with disrupted type IIa sodium-phosphate cotransporter.Glycolate Oxidase Is a Safe and Efficient Target for Substrate Reduction Therapy in a Mouse Model of Primary Hyperoxaluria Type IInhibition of Glycolate Oxidase With Dicer-substrate siRNA Reduces Calcium Oxalate Deposition in a Mouse Model of Primary Hyperoxaluria Type 1.AGXT2: a promiscuous aminotransferase.Helper-dependent adenoviral vectors for liver-directed gene therapy of primary hyperoxaluria type 1.Bone impairment in primary hyperoxaluria: a review.A novel mutation in the AGXT gene causing primary hyperoxaluria type I: genotype-phenotype correlation.An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria.Effects of alanine:glyoxylate aminotransferase variants and pyridoxine sensitivity on oxalate metabolism in a cell-based cytotoxicity assay.Biochemical analyses are instrumental in identifying the impact of mutations on holo and/or apo-forms and on the region(s) of alanine:glyoxylate aminotransferase variants associated with primary hyperoxaluria type I.In Silico Modeling of Liver Metabolism in a Human Disease Reveals a Key Enzyme for Histidine and Histamine Homeostasis.Metabolism of (13)C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase.Molecular therapy of primary hyperoxaluria.Recombinant production of eight human cytosolic aminotransferases and assessment of their potential involvement in glyoxylate metabolism.Iohexol plasma clearance, a simple and reliable method to measure renal function in conscious mice.Oxalobacter formigenes-Derived Bioactive Factors Stimulate Oxalate Transport by Intestinal Epithelial Cells.Simplified estimates of ion-activity products of calcium oxalate and calcium phosphate in mouse urine.
P2860
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P2860
Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer
description
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2006
@ast
im November 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/11/28)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/11/28)
@nl
наукова стаття, опублікована в листопаді 2006
@uk
name
Alanine-glyoxylate aminotransf ...... ds to adenoviral gene transfer
@ast
Alanine-glyoxylate aminotransf ...... ds to adenoviral gene transfer
@en
Alanine-glyoxylate aminotransf ...... ds to adenoviral gene transfer
@nl
type
label
Alanine-glyoxylate aminotransf ...... ds to adenoviral gene transfer
@ast
Alanine-glyoxylate aminotransf ...... ds to adenoviral gene transfer
@en
Alanine-glyoxylate aminotransf ...... ds to adenoviral gene transfer
@nl
prefLabel
Alanine-glyoxylate aminotransf ...... ds to adenoviral gene transfer
@ast
Alanine-glyoxylate aminotransf ...... ds to adenoviral gene transfer
@en
Alanine-glyoxylate aminotransf ...... ds to adenoviral gene transfer
@nl
P2093
P2860
P3181
P356
P1476
Alanine-glyoxylate aminotransf ...... ds to adenoviral gene transfer
@en
P2093
Alfredo Santana
Armando Torres
Eduardo C. Salido
Jayanta Roy-Chowdhury
Larry J. Shapiro
Namita Roy-Chowdhury
Xiao M. Li
P2860
P304
18249–18254
P3181
P356
10.1073/PNAS.0607218103
P407
P577
2006-11-28T00:00:00Z