about
The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic targetDown-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125LMNA knock-down affects differentiation and progression of human neuroblastoma cellsDetection of P-glycoprotein in the Golgi apparatus of drug-untreated human melanoma cells.Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90.Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma.Toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxia-inducible factor 1 alphaThe mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms.Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer.VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling.Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer.Involvement of BH4 domain of bcl-2 in the regulation of HIF-1-mediated VEGF expression in hypoxic tumor cells.Lost in translation: bridging the gap between cancer research and effective therapies.TLR3 engagement induces IRF-3-dependent apoptosis in androgen-sensitive prostate cancer cells and inhibits tumour growth in vivo.PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expressionN-methylformamide induces changes on adhesive properties and lung-colonizing potential of M14 melanoma cells.NAADP-Dependent Ca(2+) Signaling Controls Melanoma Progression, Metastatic Dissemination and NeoangiogenesisInvolvement of RB gene family in tumor angiogenesis.relA over-expression reduces tumorigenicity and activates apoptosis in human cancer cells.Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth.The thiazole derivative CPTH6 impairs autophagyAffinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein.Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells.Growth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutationsInduction of apoptosis in human cancer cells by candidaspongiolide, a novel sponge polyketide.Lonidamine induces apoptosis in drug-resistant cells independently of the p53 gene.PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer.Metabolite profiling of ascidian Styela plicata using LC-MS with multivariate statistical analysis and their antitumor activity.Non-canonical roles of Bcl-2 and Bcl-xL proteins: relevance of BH4 domain.1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells.Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ.Dual promoter usage as regulatory mechanism of let-7c expression in leukemic and solid tumors.BH4 domain of bcl-2 protein is required for its proangiogenic function under hypoxic condition.tert-Butylcarbamate-containing histone deacetylase inhibitors: apoptosis induction, cytodifferentiation, and antiproliferative activities in cancer cells.CPTH6, a thiazole derivative, induces histone hypoacetylation and apoptosis in human leukemia cells.The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis.Functional activity of CXCL8 receptors, CXCR1 and CXCR2, on human malignant melanoma progression.Involvement of nuclear factor-kappa B in bcl-xL-induced interleukin 8 expression in glioblastoma.Bcl-2 overexpression in melanoma cells increases tumor progression-associated properties and in vivo tumor growth.Enhanced antitumour efficacy of gimatecan in combination with Bcl-2 antisense oligonucleotide in human melanoma xenografts.
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description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Donatella Del Bufalo
@ast
Donatella Del Bufalo
@en
Donatella Del Bufalo
@es
Donatella Del Bufalo
@nl
Donatella Del Bufalo
@sl
type
label
Donatella Del Bufalo
@ast
Donatella Del Bufalo
@en
Donatella Del Bufalo
@es
Donatella Del Bufalo
@nl
Donatella Del Bufalo
@sl
prefLabel
Donatella Del Bufalo
@ast
Donatella Del Bufalo
@en
Donatella Del Bufalo
@es
Donatella Del Bufalo
@nl
Donatella Del Bufalo
@sl
P106
P21
P31
P496
0000-0002-3148-6096