Essential role of mouse telomerase in highly proliferative organs
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Hypoxia extends the life span of vascular smooth muscle cells through telomerase activation.Telomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumorsVault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivoTelomerase modulates Wnt signalling by association with target gene chromatinTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationIdentification of ATPases pontin and reptin as telomerase components essential for holoenzyme assemblyWild-derived inbred mouse strains have short telomeres.Human telomerase and its regulationMammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres.Identification of two RNA-binding proteins associated with human telomerase RNAComparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determinationTelomere shortening and apoptosis in telomerase-inhibited human tumor cellsFunctional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongationCrisis intervention: the role of telomeraseTelomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cellsRole of telomere dysfunction in cardiac failure in Duchenne muscular dystrophyGenetic interstitial lung diseaseRegulation of glucose metabolism by p53: emerging new roles for the tumor suppressorThe telomere syndromesTelomerase deficiency impairs glucose metabolism and insulin secretionShort telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR miceCytotoxic T cell immunity against telomerase reverse transcriptase in humansbeta1- and alpha6-integrin are surface markers on mouse spermatogonial stem cellsInvolvement of 14-3-3 proteins in nuclear localization of telomeraseThe differentiation status of primary gonadal germ cell tumors correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomeraseComplex roles for telomeres and telomerase in breast carcinogenesisTranscription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) GeneTelomeres in aging and disease: lessons from zebrafishAging of hematopoietic stem cells: DNA damage and mutations?Role of Telomerase in the Cardiovascular SystemTelomeres and telomerase as therapeutic targets to prevent and treat age-related diseasesConnecting the Dots: From DNA Damage and Repair to AgingWhen stem cells grow old: phenotypes and mechanisms of stem cell agingCellular senescence in aging and age-related disease: from mechanisms to therapyChanges in Regenerative Capacity through LifespanPredicting Risk at the End of the End: Telomere G-tail as a BiomarkerThe short and long telomere syndromes: paired paradigms for molecular medicineTelomerase and idiopathic pulmonary fibrosisPlasticity of granulosa cells: on the crossroad of stemness and transdifferentiation potentialMolecular regulation of telomerase activity in aging
P2860
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P2860
Essential role of mouse telomerase in highly proliferative organs
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Essential role of mouse telomerase in highly proliferative organs
@ast
Essential role of mouse telomerase in highly proliferative organs
@en
type
label
Essential role of mouse telomerase in highly proliferative organs
@ast
Essential role of mouse telomerase in highly proliferative organs
@en
prefLabel
Essential role of mouse telomerase in highly proliferative organs
@ast
Essential role of mouse telomerase in highly proliferative organs
@en
P2093
P3181
P356
P1433
P1476
Essential role of mouse telomerase in highly proliferative organs
@en
P2093
DePinho RA
Gottlieb GJ
Horner JW 2nd
P2888
P304
P3181
P356
10.1038/33345
P407
P577
1998-04-09T00:00:00Z
P5875
P6179
1017086815