Rho-associated kinase II (ROCKII) limits axonal growth after trauma within the adult mouse spinal cord.
about
Selective ROCK2 inhibition in focal cerebral ischemiaThe Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular DiseaseRegulation of ROCK activity in cancerSmall-molecule-induced Rho-inhibition: NSAIDs after spinal cord injuryRho family GTPases: key players in neuronal development, neuronal survival, and neurodegenerationInhibition of prostaglandin E2 receptor EP3 mitigates thrombin-induced brain injuryNeurite outgrowth of mature retinal ganglion cells and PC12 cells requires activity of CK1δ and CK1εMemory impairment in transgenic Alzheimer mice requires cellular prion protein.Intravitreal delivery of human NgR-Fc decoy protein regenerates axons after optic nerve crush and protects ganglion cells in glaucoma models.Multimodal exercises simultaneously stimulating cortical and brainstem pathways after unilateral corticospinal lesion.ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS.Rho kinase proteins display aberrant upregulation in vascular tumors and contribute to vascular tumor growth.High throughput screening of a library based on kinase inhibitor scaffolds against Mycobacterium tuberculosis H37Rv.Rho-associated coiled-coil containing kinases (ROCK): structure, regulation, and functions.Targets for neural repair therapies after strokeChemical interrogation of the neuronal kinome using a primary cell-based screening assay.Rho-kinase in development and heart failure: insights from genetic modelsA multi-domain fragment of Nogo-A protein is a potent inhibitor of cortical axon regeneration via Nogo receptor 1.Rho kinase as a therapeutic target in cardiovascular disease.Recovery from chronic spinal cord contusion after Nogo receptor intervention.Isoform diversity and its importance for axon regeneration.Myelin-derived ephrinB3 restricts axonal regeneration and recovery after adult CNS injury.Negative regulation of RhoA translation and signaling by hnRNP-Q1 affects cellular morphogenesis.Rho/ROCK pathway and neural regeneration: a potential therapeutic target for central nervous system and optic nerve damageDiscovery of a novel ROCK2 inhibitor with anti-migration effects via docking and high-content drug screening.Phenotypic Screening of Small-Molecule Inhibitors: Implications for Therapeutic Discovery and Drug Target Development in Traumatic Brain Injury.HSV-mediated gene transfer of C3 transferase inhibits Rho to promote axonal regeneration.Degeneration of phrenic motor neurons induces long-term diaphragm deficits following mid-cervical spinal contusion in mice.Plasticity Related Gene 3 (PRG3) overcomes myelin-associated growth inhibition and promotes functional recovery after spinal cord injury.Rho kinases in cardiovascular physiology and pathophysiology: the effect of fasudil.Genetic dissection of axon regeneration.ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.The role of Nogo-A in axonal plasticity, regrowth and repair.Nogo-A represses anatomical and synaptic plasticity in the central nervous system.Recent Advances towards the Clinical Application of Stem Cells for Retinal Regeneration.Astrocytic modulation of blood brain barrier: perspectives on Parkinson's disease.New Insights into the Roles of Nogo-A in CNS Biology and Diseases.Novel Approaches in Astrocyte Protection: from Experimental Methods to Computational Approaches.E11/Podoplanin Protein Stabilization Through Inhibition of the Proteasome Promotes Osteocyte Differentiation in Murine in Vitro Models.miR-124 represses ROCK1 expression to promote neurite elongation through activation of the PI3K/Akt signal pathway.
P2860
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P2860
Rho-associated kinase II (ROCKII) limits axonal growth after trauma within the adult mouse spinal cord.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Rho-associated kinase II (ROCK ...... n the adult mouse spinal cord.
@ast
Rho-associated kinase II (ROCK ...... n the adult mouse spinal cord.
@en
type
label
Rho-associated kinase II (ROCK ...... n the adult mouse spinal cord.
@ast
Rho-associated kinase II (ROCK ...... n the adult mouse spinal cord.
@en
prefLabel
Rho-associated kinase II (ROCK ...... n the adult mouse spinal cord.
@ast
Rho-associated kinase II (ROCK ...... n the adult mouse spinal cord.
@en
P2093
P2860
P1476
Rho-associated kinase II (ROCK ...... n the adult mouse spinal cord.
@en
P2093
Andre Schmandke
Antonio Schmandke
Jonathan Sigworth
Philip Duffy
Shuh Narumiya
William B J Cafferty
P2860
P304
15266-15276
P356
10.1523/JNEUROSCI.4650-09.2009
P407
P577
2009-12-01T00:00:00Z