The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression
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Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNAMultiple Export Mechanisms for mRNAsRNA Export through the NPC in EukaryotesThe role of TREX in gene expression and diseaseTHOC2 Mutations Implicate mRNA-Export Pathway in X-Linked Intellectual DisabilityArabidopsis DEAD-box RNA helicase UAP56 interacts with both RNA and DNA as well as with mRNA export factorsUAP56 is a novel interacting partner of Bcr in regulating vascular smooth muscle cell DNA synthesisUAP56 is an important mediator of angiotensin II/platelet derived growth factor induced vascular smooth muscle cell DNA synthesis and proliferationA Sub-Element in PRE enhances nuclear export of intronless mRNAs by recruiting the TREX complex via ZC3H18Regulatory functional territory of PLK-1 and their substrates beyond mitosis.An essential nuclear protein in trypanosomes is a component of mRNA transcription/export pathway.An interaction between KSHV ORF57 and UIF provides mRNA-adaptor redundancy in herpesvirus intronless mRNA export.Requirement of UAP56, URH49, RBM15, and OTT3 in the expression of Kaposi sarcoma-associated herpesvirus ORF57.A novel mechanism inducing genome instability in Kaposi's sarcoma-associated herpesvirus infected cells.The cellular RNA helicase UAP56 is required for prevention of double-stranded RNA formation during influenza A virus infectionThe consensus 5' splice site motif inhibits mRNA nuclear export.A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1.Kaposi's sarcoma-associated herpesvirus ORF57 protein: exploiting all stages of viral mRNA processing.Murine leukemia virus uses TREX components for efficient nuclear export of unspliced viral transcripts.Cip29 is phosphorylated following activation of the DNA damage response in Xenopus egg extracts.The isoflavone fraction from soybean presents mRNA maturation inhibition activity.Splicing promotes the nuclear export of β-globin mRNA by overcoming nuclear retention elements.Trafficking of mRNAs containing ALREX-promoting elements through nuclear speckles.A short conserved motif in ALYREF directs cap- and EJC-dependent assembly of export complexes on spliced mRNAsMultiple factors in the early splicing complex are involved in the nuclear retention of pre-mRNAs in mammalian cells.Plk1-mediated phosphorylation of UAP56 regulates the stability of UAP56.Genetic regulators of a pluripotent adult stem cell system in planarians identified by RNAi and clonal analysisFunctional genomics identifies a requirement of pre-mRNA splicing factors for sister chromatid cohesion.Visualization of human karyopherin beta-1/importin beta-1 interactions with protein partners in mitotic cells by co-immunoprecipitation and proximity ligation assays.TREX complex binds spliced; capped mRNA:CBC:EJC cotranscriptionallyThe Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events.Depletion of mRNA export regulator DBP5/DDX19, GLE1 or IPPK that is a key enzyme for the production of IP6, resulting in differentially altered cytoplasmic mRNA expression and specific cell defect.DDX49 is an RNA helicase that affects translation by regulating mRNA export and the levels of pre-ribosomal RNADDX3X RNA helicase affects breast cancer cell cycle progression by regulating expression of KLF4A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAsNuclear export mechanisms of circular RNAs: size does matter
P2860
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P2860
The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The closely related RNA helica ...... y regulate mitotic progression
@ast
The closely related RNA helica ...... y regulate mitotic progression
@en
type
label
The closely related RNA helica ...... y regulate mitotic progression
@ast
The closely related RNA helica ...... y regulate mitotic progression
@en
prefLabel
The closely related RNA helica ...... y regulate mitotic progression
@ast
The closely related RNA helica ...... y regulate mitotic progression
@en
P2093
P2860
P356
P1476
The closely related RNA helica ...... y regulate mitotic progression
@en
P2093
Eisuke Nishida
Hiroko Yukinaga
Masaya Nagao
Naoko Fujiwara
Noriyuki Kioka
Seiji Masuda
Taiho Kambe
Takuya Shiki
Tomohiro Yamazaki
Tomoya Kurihara
P2860
P304
P356
10.1091/MBC.E09-10-0913
P50
P577
2010-06-23T00:00:00Z