about
Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experimentsStudies on the reaction mechanism of riboflavin synthase: X-ray crystal structure of a complex with 6-carboxyethyl-7-oxo-8-ribityllumazineStructure and Properties of an Engineered Transketolase from MaizeDipeptidyl nitrile inhibitors of Cathepsin LStructural basis of the action of glucosyltransferase Lgt1 from Legionella pneumophilaThe design and synthesis of novel N-hydroxyformamide inhibitors of ADAM-TS4 for the treatment of osteoarthritisSelective non zinc binding inhibitors of MMP13Lead optimisation of selective non-zinc binding inhibitors of MMP13. Part 2MacA is a Second Cytochrome c Peroxidase of Geobacter sulfurreducensThe discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseasesStructural and functional characterisation of the methionine adenosyltransferase from Thermococcus kodakarensis4-Acyl pyrroles: mimicking acetylated lysines in histone code readingImproving coiled coil stability while maintaining specificity by a bacterial hitchhiker selection systemA Conformational Switch Triggers Nitrogenase Protection from Oxygen Damage by Shethna Protein II (FeSII)Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure-Activity Relationship Study4-Acyl Pyrrole Derivatives Yield Novel Vectors for Designing Inhibitors of the Acetyl-Lysine Recognition Site of BRD4(1)Structure-Based Development of an Affinity Probe for Sirtuin 2Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocationCrystal structure of Cdc11, a septin subunit from Saccharomyces cerevisiaeSelective Sirt2 inhibition by ligand-induced rearrangement of the active site.Preparation data of the bromodomains BRD3(1), BRD3(2), BRD4(1), and BRPF1B and crystallization of BRD4(1)-inhibitor complexes.Seeding for sirtuins: microseed matrix seeding to obtain crystals of human Sirt3 and Sirt2 suitable for soaking.Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2Structural and functional characterization of 4-hydroxyphenylpyruvate dioxygenase from the thermoacidophilic archaeon Picrophilus torridus.Design, synthesis, and evaluation of 6-carboxyalkyl and 6-phosphonoxyalkyl derivatives of 7-oxo-8-ribitylaminolumazines as inhibitors of riboflavin synthase and lumazine synthase.Incorporation of an amide into 5-phosphonoalkyl-6-D-ribitylaminopyrimidinedione lumazine synthase inhibitors results in an unexpected reversal of selectivity for riboflavin synthase vs lumazine synthase.Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.Biocatalytic Properties and Structural Analysis of Phloroglucinol Reductases.Crystal structure of an archaeal pentameric riboflavin synthase in complex with a substrate analog inhibitor: stereochemical implications.Prevention of MKK6-dependent activation by binding to p38alpha MAP kinase.A mechanism to prevent production of reactive oxygen species by Escherichia coli respiratory complex I.
P50
Q21284390-D097F2C4-550B-49BE-9C7F-BA9C926B0AAAQ27639775-BF47AA35-8DFB-42F8-BA6C-48D7FA0A1C13Q27641833-FFB22DDD-736C-4EAC-BBFA-AAA54DDA3781Q27655858-7583F042-A6C8-4968-90CA-0129183B7A7CQ27658348-3B3098D4-CE44-4AC0-99C3-DCC71B1F6FA4Q27666686-E97ADE30-99DA-450F-B416-8B86A2B0AFBFQ27670422-25F051BE-BAE0-4013-AC2B-78E7D1171097Q27676052-C86500A0-3335-4442-B729-4A43C86BDFD1Q27678047-F0BEFB22-8696-4F6F-B53C-87D4F5450A78Q27679186-9D4F7CED-7276-42A4-B666-2A5F0488AF24Q27680390-9C3ED9BC-0228-44D6-B809-239C1356E84CQ27687671-DECD5DD3-12E0-4376-BCD7-CD51C5B48E7EQ27689484-B20D0138-11E3-462F-AF7A-2473E216B006Q27703125-CF784D27-65D9-40E2-931C-11494A002AE0Q27703230-E694A4F2-3A26-422B-A398-389058D9B295Q27703416-9FF5109D-5575-4945-9D67-B391FA68DA4DQ27703530-22490F58-C4E1-4247-B19A-C1EE66F89B2EQ27703586-8BFDC459-02BC-4639-9402-BA7B97151785Q27703633-690A700D-CAC3-4593-92F6-2DF9A460A9E2Q30316777-4D6EA3EE-B555-4E86-AB69-0228ED4F0EB1Q31093919-BFFEC13A-AD83-459E-ADA5-F04DCF9A5F2EQ38936741-E721FFC4-4860-4001-AACD-A1C90BB66C66Q41865226-70FBD09D-532B-4CA5-91FB-434ED9132A2DQ43021520-28179F3E-4B46-4C25-94B9-647C9CD7F739Q44086305-8B1C0AF4-9091-4DD6-B6A7-4DBA667BE9E6Q44158086-74B0D4FA-85BB-4540-8A01-4AC351CD3B35Q45713823-FD77C44F-30A4-422D-8556-BB682E824C21Q46456123-C2961171-022E-429C-83C6-D477B2A84C18Q46792276-C2787ECC-C130-4226-A32A-BF57F9A7A159Q46846539-0FD44B2D-B27B-4D45-BA21-73196308DA12Q64882155-B079C980-59A8-4D75-B6FE-BD15CD6FB9B8
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
ricercatore
@it
հետազոտող
@hy
name
Stefan Gerhardt
@ast
Stefan Gerhardt
@en
Stefan Gerhardt
@es
Stefan Gerhardt
@fr
Stefan Gerhardt
@nl
Stefan Gerhardt
@sl
type
label
Stefan Gerhardt
@ast
Stefan Gerhardt
@en
Stefan Gerhardt
@es
Stefan Gerhardt
@fr
Stefan Gerhardt
@nl
Stefan Gerhardt
@sl
prefLabel
Stefan Gerhardt
@ast
Stefan Gerhardt
@en
Stefan Gerhardt
@es
Stefan Gerhardt
@fr
Stefan Gerhardt
@nl
Stefan Gerhardt
@sl
P214
P227
P106
P108
P21
P214
P227
P31
P496
0000-0002-9098-8475
P569
1968-01-01T00:00:00Z
P735
P7859
viaf-8289249