Positive and negative modulation of group I metabotropic glutamate receptors.

Positive and negative modulation of group I metabotropic glutamate receptors.

Item
http://www.wikidata.org/entity/Q33313112
Recent advances in the medicinal chemistry of the metabotropic glutamate receptor 1 (mGlu₁)Membrane-sensitive conformational states of helix 8 in the metabotropic Glu2 receptor, a class C GPCRN-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement.Exploration of allosteric agonism structure-activity relationships within an acetylene series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs): discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolinAllosteric modulation of metabotropic glutamate receptors.Progress toward positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).Investigating metabotropic glutamate receptor 5 allosteric modulator cooperativity, affinity, and agonism: enriching structure-function studies and structure-activity relationships.Allosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential.Metabotropic glutamate receptor 5-positive allosteric modulators for the treatment of schizophrenia (2004-2012).Discovery and SAR of a novel series of metabotropic glutamate receptor 5 positive allosteric modulators with high ligand efficiencyVirtual Screening and Molecular Dynamics Study of Potential Negative Allosteric Modulators of mGluR1 from Chinese Herbs.Synthesis and SAR of centrally active mGlu5 positive allosteric modulators based on an aryl acetylenic bicyclic lactam scaffold.Pharmacological characterization of MRZ-8676, a novel negative allosteric modulator of subtype 5 metabotropic glutamate receptors (mGluR5): focus on L: -DOPA-induced dyskinesia.Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors – A Structural Perspective of Ligands and Mutants.In vitro binding of a radio-labeled positive allosteric modulator for metabotropic glutamate receptor subtype 5.Development of 1H-Pyrazolo[3,4-b]pyridines as Metabotropic Glutamate Receptor 5 Positive Allosteric Modulators.
P2860

Positive and negative modulation of group I metabotropic glutamate receptors.

Item
http://www.wikidata.org/entity/Q33313112
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Positive and negative modulation of group I metabotropic glutamate receptors.
@ast
Positive and negative modulation of group I metabotropic glutamate receptors.
@en
Positive and negative modulation of group I metabotropic glutamate receptors.
@nl
type
label
Positive and negative modulation of group I metabotropic glutamate receptors.
@ast
Positive and negative modulation of group I metabotropic glutamate receptors.
@en
Positive and negative modulation of group I metabotropic glutamate receptors.
@nl
prefLabel
Positive and negative modulation of group I metabotropic glutamate receptors.
@ast
Positive and negative modulation of group I metabotropic glutamate receptors.
@en
Positive and negative modulation of group I metabotropic glutamate receptors.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Positive and negative modulation of group I metabotropic glutamate receptors.
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698