Global parameter search reveals design principles of the mammalian circadian clock
about
Collective timekeeping among cells of the master circadian clockCircadian systems biology: When time mattersPersistent cell-autonomous circadian oscillations in fibroblasts revealed by six-week single-cell imaging of PER2::LUC bioluminescenceModel-driven experimental approach reveals the complex regulatory distribution of p53 by the circadian factor Period 2Coupling governs entrainment range of circadian clocks.Circadian regulation of intracellular G-protein signalling mediates intercellular synchrony and rhythmicity in the suprachiasmatic nucleusQuantification of circadian rhythms in single cells.How to achieve fast entrainment? The timescale to synchronization.How to get oscillators in a multicellular clock to agree on the right period.Molecular mechanisms that regulate the coupled period of the mammalian circadian clockSuprachiasmatic nucleus: cell autonomy and network propertiesEffect of network architecture on synchronization and entrainment properties of the circadian oscillations in the suprachiasmatic nucleusLEMS: a language for expressing complex biological models in concise and hierarchical form and its use in underpinning NeuroML 2.Photic desynchronization of two subgroups of circadian oscillators in a network model of the suprachiasmatic nucleus with dispersed coupling strengths.Robust and flexible response of the Ostreococcus tauri circadian clock to light/dark cycles of varying photoperiod.Weakly circadian cells improve resynchrony.A circadian clock-regulated toggle switch explains AtGRP7 and AtGRP8 oscillations in Arabidopsis thalianaThe relationship between stochastic and deterministic quasi-steady state approximations.Noise Induces Oscillation and Synchronization of the Circadian Neurons.Heterogeneity induces rhythms of weakly coupled circadian neurons.The synchronization of neuronal oscillators determined by the directed network structure of the suprachiasmatic nucleus under different photoperiods.The effects of non-self-sustained oscillators on the en-trainment ability of the suprachiasmatic nucleus.Biophysical properties of presynaptic short-term plasticity in hippocampal neurons: insights from electrophysiology, imaging and mechanistic models.Regulating the Suprachiasmatic Nucleus (SCN) Circadian Clockwork: Interplay between Cell-Autonomous and Circuit-Level Mechanisms.Transition of phase response properties and singularity in the circadian limit cycle of cultured cells.Parameter space compression underlies emergent theories and predictive models.Entrainment range of the suprachiasmatic nucleus affected by the difference in the neuronal amplitudes between the light-sensitive and light-insensitive regions.Dissociation between two subgroups of the suprachiasmatic nucleus affected by the number of damped oscillated neurons.Impact of dispersed coupling strength on the free running periods of circadian rhythms.Measuring Relative Coupling Strength in Circadian Systems.Entrainment of the suprachiasmatic nucleus network by a light-dark cycle.Mechanism of phase splitting in two coupled groups of suprachiasmatic-nucleus neurons.Free-running period of neurons in the suprachiasmatic nucleus: Its dependence on the distribution of neuronal coupling strengths.The circadian rhythm induced by the heterogeneous network structure of the suprachiasmatic nucleus.Entrainment range of nonidentical circadian oscillators by a light-dark cycle.The proportion of light-responsive neurons determines the limit cycle properties of the suprachiasmatic nucleus.Socially synchronized circadian oscillators.Neurotransmitter-mediated collective rhythms in grouped Drosophila circadian clocks.
P2860
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P2860
Global parameter search reveals design principles of the mammalian circadian clock
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Global parameter search reveals design principles of the mammalian circadian clock
@ast
Global parameter search reveals design principles of the mammalian circadian clock
@en
Global parameter search reveals design principles of the mammalian circadian clock.
@nl
type
label
Global parameter search reveals design principles of the mammalian circadian clock
@ast
Global parameter search reveals design principles of the mammalian circadian clock
@en
Global parameter search reveals design principles of the mammalian circadian clock.
@nl
prefLabel
Global parameter search reveals design principles of the mammalian circadian clock
@ast
Global parameter search reveals design principles of the mammalian circadian clock
@en
Global parameter search reveals design principles of the mammalian circadian clock.
@nl
P2093
P2860
P356
P1433
P1476
Global parameter search reveals design principles of the mammalian circadian clock
@en
P2093
Achim Kramer
Hanspeter Herzel
James C W Locke
Pål O Westermark
P2860
P2888
P356
10.1186/1752-0509-2-22
P577
2008-02-29T00:00:00Z
P5875
P6179
1010695169