Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells
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Platelet generation in vivo and in vitrohiPSC-derived iMSCs: NextGen MSCs as an advanced therapeutically active cell resource for regenerative medicineBiomedical Application of Dental Tissue-Derived Induced Pluripotent Stem CellsInduction of pluripotency by defined factorsStem cells, megakaryocytes, and plateletsManufacturing blood ex vivo: a futuristic approach to deal with the supply and safety concernsPluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical applicationIL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs.Functional comparison of induced pluripotent stem cell- and blood-derived GPIIbIIIa deficient plateletsLarge-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programmingThree-Dimensional Environment Sustains Hematopoietic Stem Cell Differentiation into Platelet-Producing MegakaryocytesHeterozygous and homozygous JAK2(V617F) states modeled by induced pluripotent stem cells from myeloproliferative neoplasm patientsAn in vitro expansion system for generation of human iPS cell-derived hepatic progenitor-like cells exhibiting a bipotent differentiation potentialDynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potentialRethinking differentiation: stem cells, regeneration, and plasticityInducible Gata1 suppression expands megakaryocyte-erythroid progenitors from embryonic stem cells.Rapid differentiation of human pluripotent stem cells into functional neurons by mRNAs encoding transcription factors.Induced pluripotent stem cell-derived human platelets: one step closer to the clinicInfusion of megakaryocytic progenitor products generated from cord blood hematopoietic stem/progenitor cells: results of the phase 1 study.Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling.Efficient generation of megakaryocytes from human induced pluripotent stem cells using food and drug administration-approved pharmacological reagents.Manipulating megakaryocytes to manufacture platelets ex vivo.A novel bioreactor and culture method drives high yields of platelets from stem cells.Generation of HLA-universal iPSCs-derived megakaryocytes and platelets for survival under refractoriness conditions.Platelet bioreactor: accelerated evolution of design and manufacture.Refined methods to evaluate the in vivo hemostatic function and viability of transfused human platelets in rabbit models.Generation of germline-competent rat induced pluripotent stem cells.Development of Sendai virus vectors and their potential applications in gene therapy and regenerative medicine.In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells.Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation.The incredible journey: From megakaryocyte development to platelet formation.Immortalization of erythroblasts by c-MYC and BCL-XL enables large-scale erythrocyte production from human pluripotent stem cellsManipulation of KLF4 expression generates iPSCs paused at successive stages of reprogrammingEpstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression.Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium.OP9 bone marrow stroma cells differentiate into megakaryocytes and platelets.Road blocks in making platelets for transfusionGeneration of Col2a1-EGFP iPS cells for monitoring chondrogenic differentiation.Profiling of microRNA in human and mouse ES and iPS cells reveals overlapping but distinct microRNA expression patterns.Humanizing thrombi in mice.
P2860
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P1343
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P2860
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Transient activation of c-MYC ...... induced pluripotent stem cells
@ast
Transient activation of c-MYC ...... induced pluripotent stem cells
@en
type
label
Transient activation of c-MYC ...... induced pluripotent stem cells
@ast
Transient activation of c-MYC ...... induced pluripotent stem cells
@en
prefLabel
Transient activation of c-MYC ...... induced pluripotent stem cells
@ast
Transient activation of c-MYC ...... induced pluripotent stem cells
@en
P2093
P2860
P4510
P50
P356
P1476
Transient activation of c-MYC ...... induced pluripotent stem cells
@en
P2093
Akira Sawaguchi
Hiromitsu Nakauchi
Hiroshi Endo
Kazutoshi Takahashi
Ken Nishimura
Naoya Takayama
Ryoko Ohnishi
Ryozo Nagai
Satoshi Nishimura
P2860
P304
P356
10.1084/JEM.20100844
P407
P577
2010-11-22T00:00:00Z