about
The emerging link between O-GlcNAcylation and neurological disorders.Modeling tau pathology in human stem cell derived neurons.Alzheimer's disease pathological lesions activate the spleen tyrosine kinase.Hippocampal neurophysiology is modified by a disease-associated C-terminal fragment of tau protein.Soluble Tau has devastating effects on the structural plasticity of hippocampal granule neurons.Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms.Atypical, non-standard functions of the microtubule associated Tau protein.What is the evidence that tau pathology spreads through prion-like propagation?Imbalances in the Hsp90 Chaperone Machinery: Implications for Tauopathies.Distinct differences in prion-like seeding and aggregation between tau protein variants provide mechanistic insights into tauopathies.The Microtubule-Associated Protein Tau Mediates the Organization of Microtubules and Their Dynamic Exploration of Actin-Rich Lamellipodia and Filopodia of Cortical Growth Cones.Our Working Point of View of Tau Protein.Tau Diagnostics and Clinical Studies.Small-molecule PET Tracers for Imaging Proteinopathies.Regulation of brain insulin signaling: A new function for tau.Ratio of β-amyloid protein (Aβ) and Tau predicts the postoperative cognitive dysfunction on patients undergoing total hip/knee replacement surgery.Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease.An N-terminal motif unique to primate tau enables differential protein-protein interactions.The Role of Insulin/IGF-1/PI3K/Akt/GSK3β Signaling in Parkinson's Disease Dementia.Vesicular Axonal Transport is Modified In Vivo by Tau Deletion or Overexpression in Drosophila.Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?An Overview on the Clinical Development of Tau-Based Therapeutics.Tau Proteolysis in the Pathogenesis of Tauopathies: Neurotoxic Fragments and Novel Biomarkers.Novel monoclonal antibodies targeting the microtubule-binding domain of human tau.Biological function of Lemur tyrosine kinase 2 (LMTK2): implications in neurodegeneration.A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies.Pyk2 is a Novel Tau Tyrosine Kinase that is Regulated by the Tyrosine Kinase Fyn.Extracellular Monomeric and Aggregated Tau Efficiently Enter Human Neurons through Overlapping but Distinct Pathways.Preparation of organotypic brain slice cultures for the study of Alzheimer's disease.Directed evolution of a picomolar-affinity, high-specificity antibody targeting phosphorylated tauQuestions concerning the role of amyloid-β in the definition, aetiology and diagnosis of Alzheimer's diseaseA Closer Look into the Role of Protein Tau in the Identification of Promising Therapeutic Targets for Alzheimer's DiseaseCharacterisation of tau in the human and rodent enteric nervous system under physiological conditions and in tauopathyInflammation as a central mechanism in Alzheimer's diseaseTau in Oligodendrocytes Takes Neurons in Sickness and in Health
P2860
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P248
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P2860
description
2017 nî lūn-bûn
@nan
2017 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2017 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
name
Roles of tau protein in health and disease.
@ast
Roles of tau protein in health and disease.
@en
Roles of tau protein in health and disease.
@nl
type
label
Roles of tau protein in health and disease.
@ast
Roles of tau protein in health and disease.
@en
Roles of tau protein in health and disease.
@nl
prefLabel
Roles of tau protein in health and disease.
@ast
Roles of tau protein in health and disease.
@en
Roles of tau protein in health and disease.
@nl
P2860
P50
P921
P1476
Roles of tau protein in health and disease.
@en
P2860
P2888
P304
P356
10.1007/S00401-017-1707-9
P5008
P577
2017-04-06T00:00:00Z
2017-05-01T00:00:00Z
P6179
1084517741