Activation of the unfolded protein response contributes toward the antitumor activity of vorinostat.
about
Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylationDinosaurs and ancient civilizations: reflections on the treatment of cancerEndoplasmic reticulum stress plays a pivotal role in cell death mediated by the pan-deacetylase inhibitor panobinostat in human hepatocellular cancer cells.Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers.Proteomic analysis identifies differentially expressed proteins after HDAC vorinostat and EGFR inhibitor gefitinib treatments in Hep-2 cancer cells.The interconnectedness of cancer cell signaling.Class I histone deacetylases localize to the endoplasmic reticulum and modulate the unfolded protein response.Dual Targeting of Protein Degradation Pathways with the Selective HDAC6 Inhibitor ACY-1215 and Bortezomib Is Synergistic in Lymphoma.The metabolomic signature of malignant glioma reflects accelerated anabolic metabolismThe role of endoplasmic reticulum stress in maintaining and targeting multiple myeloma: a double-edged sword of adaptation and apoptosis.Histone deacetylase inhibitors interact with melanoma differentiation associated-7/interleukin-24 to kill primary human glioblastoma cells.Acetylation modification regulates GRP78 secretion in colon cancer cells.Molecular and cellular effects of a novel hydroxamate-based HDAC inhibitor - belinostat - in glioblastoma cell lines: a preliminary report.Down-modulation of SEL1L, an unfolded protein response and endoplasmic reticulum-associated degradation protein, sensitizes glioma stem cells to the cytotoxic effect of valproic acid.Combining histone deacetylase inhibitors with MDA-7/IL-24 enhances killing of renal carcinoma cellsGlucose-regulated proteins in cancer: molecular mechanisms and therapeutic potentialUnderlying mechanisms and chemical/biochemical therapeutic approaches to ameliorate protein misfolding neurodegenerative diseases.Targeting the hallmarks of cancer with therapy-induced endoplasmic reticulum (ER) stress.Selective, potent blockade of the IRE1 and ATF6 pathways by 4-phenylbutyric acid analogues.Targeting radiation-induced G(2) checkpoint activation with the Wee-1 inhibitor MK-1775 in glioblastoma cell lines.HDAC pharmacological inhibition promotes cell death through the eIF2α kinases PKR and GCN2.Deacetylase inhibitors - focus on non-histone targets and effects.Overcoming intratumor heterogeneity of polygenic cancer drug resistance with improved biomarker integrationActivating Transcription Factor 3 regulates in part the enhanced tumour cell cytotoxicity of the histone deacetylase inhibitor M344 and cisplatin in combinationEncephalitis is mediated by ROP18 of Toxoplasma gondii, a severe pathogen in AIDS patients.
P2860
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P2860
Activation of the unfolded protein response contributes toward the antitumor activity of vorinostat.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Activation of the unfolded pro ...... itumor activity of vorinostat.
@ast
Activation of the unfolded pro ...... itumor activity of vorinostat.
@en
Activation of the unfolded pro ...... itumor activity of vorinostat.
@nl
type
label
Activation of the unfolded pro ...... itumor activity of vorinostat.
@ast
Activation of the unfolded pro ...... itumor activity of vorinostat.
@en
Activation of the unfolded pro ...... itumor activity of vorinostat.
@nl
prefLabel
Activation of the unfolded pro ...... itumor activity of vorinostat.
@ast
Activation of the unfolded pro ...... itumor activity of vorinostat.
@en
Activation of the unfolded pro ...... itumor activity of vorinostat.
@nl
P2093
P2860
P356
P1433
P1476
Activation of the unfolded pro ...... itumor activity of vorinostat.
@en
P2093
Bhaswati Sarcar
Eli S Williams
John M Koomen
Philip J Tofilon
Prakash Chinnaiyan
Soumen Kahali
P2860
P356
10.1593/NEO.91422
P577
2010-01-01T00:00:00Z