Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner.
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Molecular functions of thyroid hormones and their clinical significance in liver-related diseasesIntegrated regulation of hepatic metabolism by fibroblast growth factor 21 (FGF21) in vivoFibroblast Growth Factor 21 Protects against Atherosclerosis via Fine-Tuning the Multiorgan CrosstalkCross-talk between the thyroid and liver: a new target for nonalcoholic fatty liver disease treatmentTranscriptional regulation of fibroblast growth factor 21 expressionGenomic and metabolic responses to methionine-restricted and methionine-restricted, cysteine-supplemented diets in Fischer 344 rat inguinal adipose tissue, liver and quadriceps muscleThyroid hormone regulation of metabolismNon-alcoholic fatty liver disease and thyroid dysfunction: a systematic review.Transcriptional repressor E4-binding protein 4 (E4BP4) regulates metabolic hormone fibroblast growth factor 21 (FGF21) during circadian cycles and feeding.Fibroblast growth factor 21 is a metabolic regulator that plays a role in the adaptation to ketosis.Disruption of thyroid hormone activation in type 2 deiodinase knockout mice causes obesity with glucose intolerance and liver steatosis only at thermoneutralityGlucocorticoids regulate the metabolic hormone FGF21 in a feed-forward loop.Responsiveness to thyroid hormone and to ambient temperature underlies differences between brown adipose tissue and skeletal muscle thermogenesis in a mouse model of diet-induced obesity.Growth hormone induces hepatic production of fibroblast growth factor 21 through a mechanism dependent on lipolysis in adipocytes.Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3.Desensitization and Incomplete Recovery of Hepatic Target Genes After Chronic Thyroid Hormone Treatment and Withdrawal in Male Adult MiceMouse betaine-homocysteine S-methyltransferase deficiency reduces body fat via increasing energy expenditure and impairing lipid synthesis and enhancing glucose oxidation in white adipose tissueThyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans.Recruitment of histone methyltransferase G9a mediates transcriptional repression of Fgf21 gene by E4BP4 protein.Using in vivo electroporation to identify hepatic LDL receptor promoter elements and transcription factors mediating activation of transcription by T3.Fibroblast growth factor 21 and thyroid hormone show mutual regulatory dependency but have independent actions in vivo.Organelle dysfunction in hepatitis C virus-associated steatosis: anything to learn from nonalcoholic steatohepatitis?Therapeutic potential of the endocrine fibroblast growth factors FGF19, FGF21 and FGF23.Somatic cell plasticity and Niemann-pick type C2 protein: adipocyte differentiation and function.A combined docosahexaenoic acid-thyroid hormone protocol upregulates rat liver β-Klotho expression and downstream components of FGF21 signaling as a potential novel approach to metabolic stress conditions.Neohesperidin Exerts Lipid-Regulating Effects in vitro and in vivo via Fibroblast Growth Factor 21 and AMP-Activated Protein Kinase/Sirtuin Type 1/Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1α Signaling Axis.Upregulation of rat liver PPARα-FGF21 signaling by a docosahexaenoic acid and thyroid hormone combined protocol.Direct effects of thyroid hormones on hepatic lipid metabolism.
P2860
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P2860
Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner.
description
2010 nî lūn-bûn
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2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Thyroid hormone regulates hepa ...... a PPARalpha-dependent manner.
@ast
Thyroid hormone regulates hepa ...... a PPARalpha-dependent manner.
@en
type
label
Thyroid hormone regulates hepa ...... a PPARalpha-dependent manner.
@ast
Thyroid hormone regulates hepa ...... a PPARalpha-dependent manner.
@en
prefLabel
Thyroid hormone regulates hepa ...... a PPARalpha-dependent manner.
@ast
Thyroid hormone regulates hepa ...... a PPARalpha-dependent manner.
@en
P2093
P2860
P356
P1476
Thyroid hormone regulates hepa ...... a PPARalpha-dependent manner.
@en
P2093
Andrew C Adams
Anthony N Hollenberg
Ffolliott M Fisher
Inna Astapova
Jeffrey S Flier
Katherine E Kurgansky
Michael K Badman
P2860
P304
14078-14082
P356
10.1074/JBC.C110.107375
P407
P577
2010-03-17T00:00:00Z