Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.
about
The Targeted SMAC Mimetic SW IV-134 is a strong enhancer of standard chemotherapy in pancreatic cancerEffect of DAPK1 gene on proliferation, migration, and invasion of carcinoma of pancreas BxPC-3 cell line.Dual subcellular compartment delivery of doxorubicin to overcome drug resistant and enhance antitumor activity.The sigma-2 receptor as a therapeutic target for drug delivery in triple negative breast cancer.SW43-DOX ± loading onto drug-eluting bead, a potential new targeted drug delivery platform for systemic and locoregional cancer treatment - An in vitro evaluationMesothelin's minimal MUC16 binding moiety converts TR3 into a potent cancer therapeutic via hierarchical binding events at the plasma membraneConjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic.Small Molecules for Active Targeting in Cancer.The Evolution of the Sigma-2 (σ2) Receptor from Obscure Binding Site to Bona Fide Therapeutic Target.
P2860
Q28468300-D066076B-3CA5-49CC-82A8-932D3CFB011CQ34732948-3CA853EF-0761-43AC-A8AA-FE914774C92FQ36245928-B9FC00BB-AD38-476C-A359-6BA1E4B77A15Q36551212-33E54EF0-011A-497B-A013-2D25081F23AFQ37150075-F381E4DA-FE1E-473C-8F33-856038E58183Q37327815-0BD2C6E1-C911-4721-9EF4-90ECD322EB18Q37376094-340923DE-BC1F-456E-AC26-6C3DE6AB26FAQ38780383-77953328-09B0-487F-8E4F-6B1CCE122543Q38896673-9870A563-F5A8-4A6A-84FC-BE37C43FFEAD
P2860
Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.
@ast
Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.
@en
type
label
Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.
@ast
Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.
@en
prefLabel
Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.
@ast
Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.
@en
P2093
P2860
P1433
P1476
Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.
@en
P2093
Dirk Spitzer
Gunjal Garg
John R Hornick
Mary C Hornick
Peter Goedegebuure
Robert H Mach
Suwanna Vangveravong
William G Hawkins
Yassar M Hashim
P2860
P304
P356
10.1016/J.MOLONC.2014.03.005
P577
2014-03-26T00:00:00Z