Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134. - Wikidata - wikimedia - TriplyDB

Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.

Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.

http://www.wikidata.org/entity/Q33849311

about

The Targeted SMAC Mimetic SW IV-134 is a strong enhancer of standard chemotherapy in pancreatic cancer Effect of DAPK1 gene on proliferation, migration, and invasion of carcinoma of pancreas BxPC-3 cell line.Dual subcellular compartment delivery of doxorubicin to overcome drug resistant and enhance antitumor activity.The sigma-2 receptor as a therapeutic target for drug delivery in triple negative breast cancer.SW43-DOX ± loading onto drug-eluting bead, a potential new targeted drug delivery platform for systemic and locoregional cancer treatment - An in vitro evaluation Mesothelin's minimal MUC16 binding moiety converts TR3 into a potent cancer therapeutic via hierarchical binding events at the plasma membrane Conjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic.Small Molecules for Active Targeting in Cancer.The Evolution of the Sigma-2 (σ2) Receptor from Obscure Binding Site to Bona Fide Therapeutic Target.

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Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.

http://www.wikidata.org/entity/Q33849311

description

2014 nî lūn-bûn

@nan

2014 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.

@ast

Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.

@en

type

label

Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.

@ast

Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.

@en

prefLabel

Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.

@ast

Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.

@en

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P356

J.MOLONC.2014.03.005

P1433

Molecular Oncology

P1476

Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.

@en

P2093

Dirk Spitzer

http://www.w3.org/2001/XMLSchema#string

Gunjal Garg

http://www.w3.org/2001/XMLSchema#string

John R Hornick

http://www.w3.org/2001/XMLSchema#string

Mary C Hornick

http://www.w3.org/2001/XMLSchema#string

Peter Goedegebuure

http://www.w3.org/2001/XMLSchema#string

Robert H Mach

http://www.w3.org/2001/XMLSchema#string

Suwanna Vangveravong

http://www.w3.org/2001/XMLSchema#string

William G Hawkins

http://www.w3.org/2001/XMLSchema#string

Yassar M Hashim

http://www.w3.org/2001/XMLSchema#string

P2860

Mechanism of XIAP-mediated inhibition of caspase-9

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

X-linked IAP is a direct inhibitor of cell-death proteases

Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs

Structure-Based Design, Synthesis, Evaluation, and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-linked Inhibitor of Apoptosis Protein (XIAP) †

Cancer statistics, 2012

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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956-967

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scholarly article

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10.1016/J.MOLONC.2014.03.005

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5

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8

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2014-03-26T00:00:00Z

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24731702

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P932

4082741

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