Schizosaccharomyces pombe pfh1+ encodes an essential 5' to 3' DNA helicase that is a member of the PIF1 subfamily of DNA helicases.
about
The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activityThe yeast Pif1p helicase removes telomerase from telomeric DNA.Characterization of recombinant Saccharomyces cerevisiae telomerase core enzyme purified from yeast.Def1p is involved in telomere maintenance in budding yeast.The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiaeMurine Pif1 interacts with telomerase and is dispensable for telomere function in vivoThe TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasisCrystal structures of the BsPif1 helicase reveal that a major movement of the 2B SH3 domain is required for DNA unwindingPif1 helicase directs eukaryotic Okazaki fragments toward the two-nuclease cleavage pathway for primer removal.Pif1 helicase lengthens some Okazaki fragment flaps necessitating Dna2 nuclease/helicase action in the two-nuclease processing pathway.TbPIF5 is a Trypanosoma brucei mitochondrial DNA helicase involved in processing of minicircle Okazaki fragments.Unwinding the functions of the Pif1 family helicases.Reconstitution of eukaryotic lagging strand DNA replication.A genomewide screen for suppressors of Alu-mediated rearrangements reveals a role for PIF1Telomeres: structures in need of unwinding.The fission yeast pfh1(+) gene encodes an essential 5' to 3' DNA helicase required for the completion of S-phaseThe amino terminus of the Saccharomyces cerevisiae DNA helicase Rrm3p modulates protein function altering replication and checkpoint activityThe Pif1 family helicase Pfh1 facilitates telomere replication and has an RPA-dependent role during telomere lengthening.DNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S. pombe Pfh1 helicase.Roles of Pif1-like helicases in the maintenance of genomic stability.DNA repair at telomeres: keeping the ends intact.Biochemical analysis of human PIF1 helicase and functions of its N-terminal domain.Telomerase is essential to alleviate pif1-induced replication stress at telomeres.Genetic and biochemical analyses of Pfh1 DNA helicase function in fission yeastRegulation of telomere addition at DNA double-strand breaks.To peep into Pif1 helicase: multifaceted all the way from genome stability to repair-associated DNA synthesis.Getting it done at the ends: Pif1 family DNA helicases and telomeres.Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress.The functions of the multi-tasking Pfh1Pif1 helicase.De novo telomere formation is suppressed by the Mec1-dependent inhibition of Cdc13 accumulation at DNA breaks.G-rich telomeric and ribosomal DNA sequences from the fission yeast genome form stable G-quadruplex DNA structures in vitro and are unwound by the Pfh1 DNA helicaseThe Schizosaccharomyces pombe Pfh1p DNA helicase is essential for the maintenance of nuclear and mitochondrial DNA.
P2860
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P2860
Schizosaccharomyces pombe pfh1+ encodes an essential 5' to 3' DNA helicase that is a member of the PIF1 subfamily of DNA helicases.
description
2002 nî lūn-bûn
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2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2002 թվականի հունիսին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
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2002年論文
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2002年论文
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name
Schizosaccharomyces pombe pfh1 ...... F1 subfamily of DNA helicases.
@ast
Schizosaccharomyces pombe pfh1 ...... F1 subfamily of DNA helicases.
@en
type
label
Schizosaccharomyces pombe pfh1 ...... F1 subfamily of DNA helicases.
@ast
Schizosaccharomyces pombe pfh1 ...... F1 subfamily of DNA helicases.
@en
prefLabel
Schizosaccharomyces pombe pfh1 ...... F1 subfamily of DNA helicases.
@ast
Schizosaccharomyces pombe pfh1 ...... F1 subfamily of DNA helicases.
@en
P2093
P2860
P356
P1476
Schizosaccharomyces pombe pfh1 ...... F1 subfamily of DNA helicases.
@en
P2093
Ellen K Monson
Jin-Qiu Zhou
Virginia A Zakian
P2860
P304
P356
10.1091/MBC.02-02-0021
P577
2002-06-01T00:00:00Z