Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo - Wikidata - wikimedia - TriplyDB

Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo

Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo

http://www.wikidata.org/entity/Q33992515

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Molecular crosstalk between apoptosis, necroptosis, and survival signaling An outline of necrosome triggers Apoptosis, Necrosis, and Necroptosis in the Gut and Intestinal Homeostasis Death in the fast lane: what's next for necroptosis?Ubiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of Homeostasis The two faces of receptor interacting protein kinase-1 Programmed necrosis in the cross talk of cell death and inflammation NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.Programmed cell death and its role in inflammation RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis.Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination Characterization of a novel androgen receptor (AR) coregulator RIPK1 and related chemicals that suppress AR-mediated prostate cancer growth via peptide and chemical screening.NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions.Necroptosis: an alternative cell death program defending against cancer.CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN.RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4.RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury.Inhibition of Receptor-Interacting Protein Kinase 1 with Necrostatin-1s ameliorates disease progression in elastase-induced mouse abdominal aortic aneurysm model.Epithelial Cell Death and Inflammation in Skin.A tale of two domains - a structural perspective of the pseudokinase, MLKL.Emerging Roles for RIPK1 and RIPK3 in Pathogen-Induced Cell Death and Host Immunity.The Receptor-interacting Serine/Threonine Protein Kinase 1 (RIPK1) Regulates Progranulin Levels.RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.Necrosome core machinery: MLKL.Generation of small molecules to interfere with regulated necrosis.Necroptosis-independent signaling by the RIP kinases in inflammation.Post-translational control of RIPK3 and MLKL mediated necroptotic cell death.Necroptosis: A Novel Cell Death Modality and Its Potential Relevance for Critical Care Medicine.RIPK1 and PGAM5 Control Leishmania Replication through Distinct Mechanisms.Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis.Non-kinase targets of protein kinase inhibitors.Initiation and execution mechanisms of necroptosis: an overview.Necroptosis in neurodegenerative diseases: a potential therapeutic target.RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense.Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-β Synthesis Induced by Lipopolysaccharide.Necroptosis: Mechanisms and Relevance to Disease.

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Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo

http://www.wikidata.org/entity/Q33992515

description

2014 nî lūn-bûn

@nan

2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հուլիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Cutting edge: RIPK1 Kinase ina ...... NF-induced necroptosis in vivo

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Cutting edge: RIPK1 Kinase ina ...... NF-induced necroptosis in vivo

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type

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Cutting edge: RIPK1 Kinase ina ...... NF-induced necroptosis in vivo

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Cutting edge: RIPK1 Kinase ina ...... NF-induced necroptosis in vivo

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Cutting edge: RIPK1 Kinase ina ...... NF-induced necroptosis in vivo

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Cutting edge: RIPK1 Kinase ina ...... NF-induced necroptosis in vivo

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JIMMUNOL.1400590

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Journal of Immunology

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Cutting edge: RIPK1 Kinase ina ...... NF-induced necroptosis in vivo

@en

P2093

Chun Kim

http://www.w3.org/2001/XMLSchema#string

Francis K M Chan

http://www.w3.org/2001/XMLSchema#string

Justine Roderick

http://www.w3.org/2001/XMLSchema#string

Matija Zelic

http://www.w3.org/2001/XMLSchema#string

Michelle A Kelliher

http://www.w3.org/2001/XMLSchema#string

Nicole Hermance

http://www.w3.org/2001/XMLSchema#string

Thomas H Lee

http://www.w3.org/2001/XMLSchema#string

Trieu-My Van

http://www.w3.org/2001/XMLSchema#string

P2860

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

TNF-alpha induces two distinct caspase-8 activation pathways

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation

Caspase 8 inhibits programmed necrosis by processing CYLD

Identification of RIP1 kinase as a specific cellular target of necrostatins

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

Regulated necrosis: the expanding network of non-apoptotic cell death pathways.

The role of the death-domain kinase RIP in tumour-necrosis-factor-induced activation of mitogen-activated protein kinases

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation.

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1539-1543

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scholarly article

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10.4049/JIMMUNOL.1400590

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P433

4

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P478

193

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Manolis Pasparakis

Apostolos Polykratis

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25015821

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4119562

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