Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells.
about
Cytotoxic CD4 T cells in antiviral immunityInterleukin-2 receptor signaling: at the interface between tolerance and immunityIL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiationEffector, Memory, and Dysfunctional CD8(+) T Cell Fates in the Antitumor Immune ResponseThe Differentiation and Protective Function of Cytolytic CD4 T Cells in Influenza InfectionThe Role of Invariant Natural Killer T Cells in Dendritic Cell Licensing, Cross-Priming, and Memory CD8(+) T Cell GenerationThe effects of TLR activation on T-cell development and differentiationSorting through subsets: which T-cell populations mediate highly effective adoptive immunotherapy?Heterogeneity in immune responses: from populations to single cellsCIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes InfectionIL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signalsImproving Adoptive T Cell Therapy: The Particular Role of T Cell Costimulation, Cytokines, and Post-Transfer VaccinationProtective immunity to liver-stage malariaCytotoxic CD4 T Cells: Differentiation, Function, and Application to Dengue Virus InfectionmicroRNAs function in CD8+T cell biologyDephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complexMolecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profileSecondary T cell–T cell synaptic interactions drive the differentiation of protective CD8+ T cellsCD70 and IFN-1 selectively induce eomesodermin or T-bet and synergize to promote CD8+ T-cell responses.Distinct dendritic cell subsets dictate the fate decision between effector and memory CD8(+) T cell differentiation by a CD24-dependent mechanism.Cytokine-dependent induction of CD4+ T cells with cytotoxic potential during influenza virus infection.CD4+ T cell help and innate-derived IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLsCD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesisPerforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control.α4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets.Characterization of T-bet and eomes in peripheral human immune cellsIL-2 mediates CD4+ T cell help in the breakdown of memory-like CD8+ T cell tolerance under lymphopenic conditionsImmune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) and IPEX-related disorders: an evolving web of heritable autoimmune diseases.Signal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8+ T cells by preventing terminal effector differentiation.TLR4 ligands lipopolysaccharide and monophosphoryl lipid a differentially regulate effector and memory CD8+ T Cell differentiation.Challenges and developing solutions for increasing the benefits of IL-2 treatment in tumor therapy.Gamma(c) deficiency precludes CD8+ T cell memory despite formation of potent T cell effectors.Prolonged antigen presentation by immune complex-binding dendritic cells programs the proliferative capacity of memory CD8 T cells.Expression, production, and renaturation of a functional single-chain variable antibody fragment (scFv) against human ICAM-1Early events governing memory CD8+ T-cell differentiation.Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8(+) T cell differentiation.Transcriptional control of effector and memory CD8+ T cell differentiation.Inflammation programs self-reactive CD8+ T cells to acquire T-box-mediated effector function but does not prevent deletional tolerancec-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells.Redirecting the immune response: role of adoptive T cell therapy.
P2860
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P2860
Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Interleukin-2 and inflammation ...... of effector cytolytic T cells.
@ast
Interleukin-2 and inflammation ...... of effector cytolytic T cells.
@en
Interleukin-2 and inflammation ...... of effector cytolytic T cells.
@nl
type
label
Interleukin-2 and inflammation ...... of effector cytolytic T cells.
@ast
Interleukin-2 and inflammation ...... of effector cytolytic T cells.
@en
Interleukin-2 and inflammation ...... of effector cytolytic T cells.
@nl
prefLabel
Interleukin-2 and inflammation ...... of effector cytolytic T cells.
@ast
Interleukin-2 and inflammation ...... of effector cytolytic T cells.
@en
Interleukin-2 and inflammation ...... of effector cytolytic T cells.
@nl
P2093
P2860
P1433
P1476
Interleukin-2 and inflammation ...... of effector cytolytic T cells.
@en
P2093
Anjana Rao
Fernando Cruz-Guilloty
Jilian A Sacks
Mathias G Lichtenheld
Matthew E Pipkin
Michael J Bevan
P2860
P356
10.1016/J.IMMUNI.2009.11.012
P407
P577
2010-01-21T00:00:00Z