Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats.
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Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical ModelsDose-Independent ADME Properties and Tentative Identification of Metabolites of α-Mangostin from Garcinia mangostana in Mice by Automated Microsampling and UPLC-MS/MS MethodsThe use of ROC analysis for the qualitative prediction of human oral bioavailability from animal data.Recent advances in pharmacokinetic extrapolation from preclinical data to humans.Prediction of hepatic clearance in human from in vitro data for successful drug development.Practical anticipation of human efficacious doses and pharmacokinetics using in vitro and preclinical in vivo data.Intestinal permeability of metformin using single-pass intestinal perfusion in rats.Revisiting the rule of five on the basis of pharmacokinetic data from rat.A new approach for pharmacokinetic studies of natural products: measurement of isoliquiritigenin levels in mice plasma, urine and feces using modified automated dosing/blood sampling system.Prediction of human pharmacokinetics--gut-wall metabolism.Issues related to the use of canines in toxicologic pathology--issues with pharmacokinetics and metabolism.The use of biopharmaceutic classification of drugs in drug discovery and development: current status and future extension.Intestinal absorption characteristics of imperialine: in vitro and in situ assessments.PXR/CYP3A4-humanized mice for studying drug-drug interactions involving intestinal P-glycoprotein.Prediction of human pharmacokinetics--gastrointestinal absorption.Impact of physiological, physicochemical and biopharmaceutical factors in absorption and metabolism mechanisms on the drug oral bioavailability of rats and humans.Predictive models for oral drug absorption: from in silico methods to integrated dynamical models.Prediction of human pharmacokinetics-biliary and intestinal clearance and enterohepatic circulation.Surface-modified solid lipid nanoparticles for oral delivery of docetaxel: enhanced intestinal absorption and lymphatic uptake.Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination.Mitigating permeability-mediated risks in drug discovery.Current drug discovery strategies for treatment of hepatitis C virus infection.Approaches for predicting human pharmacokinetics using interspecies pharmacokinetic scaling.Pros and cons of methods used for the prediction of oral drug absorption.Identification of a novel, non-tetrahydroquinoline variant of the cholesteryl ester transfer protein (CETP) inhibitor torcetrapib, with improved aqueous solubility.Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions.Clinical pharmacokinetics of the cyclooxygenase inhibiting nitric oxide donator (CINOD) AZD3582.Prediction of human pharmacokinetics--evaluation of methods for prediction of hepatic metabolic clearance.Fasting increases tobramycin oral absorption in miceIn vitro prediction of human intestinal absorption and blood-brain barrier partitioning: development of a lipid analog for micellar liquid chromatography.Evaluation of a single-pass intestinal-perfusion method in rat for the prediction of absorption in man.Enantioselective and nonlinear intestinal absorption of eflornithine in the rat.Development and characterization of gastroretentive sustained-release formulation by combination of swelling and mucoadhesive approach: a mechanistic study.Curcumin Regulates Colon Cancer by Inhibiting P-Glycoprotein in In-situ Cancerous Colon Perfusion Rat Model.The fraction dose absorbed, in humans, and high jejunal human permeability relationship.Interspecies modeling and prediction of human exenatide pharmacokineticsAnimal versus human oral drug bioavailability: do they correlate?In situ intestinal permeability and in vivo oral bioavailability of celecoxib in supersaturating self-emulsifying drug delivery system.Effects of cysteine on the pharmacokinetics of docetaxel in rats with protein-calorie malnutrition.Estimation of absorption parameters from the non-steady-state phase in the rat gut perfusion model.
P2860
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P2860
Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats.
description
1998 nî lūn-bûn
@nan
1998 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Linear correlation of the frac ...... drugs between humans and rats.
@ast
Linear correlation of the frac ...... drugs between humans and rats.
@en
Linear correlation of the frac ...... drugs between humans and rats.
@nl
type
label
Linear correlation of the frac ...... drugs between humans and rats.
@ast
Linear correlation of the frac ...... drugs between humans and rats.
@en
Linear correlation of the frac ...... drugs between humans and rats.
@nl
prefLabel
Linear correlation of the frac ...... drugs between humans and rats.
@ast
Linear correlation of the frac ...... drugs between humans and rats.
@en
Linear correlation of the frac ...... drugs between humans and rats.
@nl
P356
P1476
Linear correlation of the frac ...... drugs between humans and rats.
@en
P2093
P304
P356
10.1023/A:1011981317451
P577
1998-11-01T00:00:00Z