Modified dsRNAs that are not processed by Dicer maintain potency and are incorporated into the RISC
about
Progress toward in vivo use of siRNAs-IIPotent and systematic RNAi mediated silencing with single oligonucleotide compounds.Enzymatically produced pools of canonical and Dicer-substrate siRNA molecules display comparable gene silencing and antiviral activities against herpes simplex virus.PHDcleav: a SVM based method for predicting human Dicer cleavage sites using sequence and secondary structure of miRNA precursors.Evaluation of canonical siRNA and Dicer substrate RNA for inhibition of hepatitis C virus genome replication--a comparative study.Functionally enhanced siRNA targeting TNFα attenuates DSS-induced colitis and TLR-mediated immunostimulation in mice.Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivoStructural diversity repertoire of gene silencing small interfering RNAs.42- and 63-bp anti-MDR1-siRNAs bearing 2'-OMe modifications in nuclease-sensitive sites induce specific and potent gene silencing.Enhanced intracellular delivery and multi-target gene silencing triggered by tripodal RNA structures.Nuclease-resistant 63-bp trimeric siRNAs simultaneously silence three different genes in tumor cells.Diverse spontaneous silencing of a transgene among two Nicotiana species.
P2860
Q28255877-3E4E8051-E9B7-4BB1-A968-CEFFDF469B09Q34178422-EDB43025-2EC3-45A5-A3A8-35C0F381CD46Q34506213-9D902104-6AE0-4B14-AC02-2B8091442781Q35051011-3C75C420-AC6A-496C-9528-2C9BB2A16022Q35565539-8C096236-6562-46AC-9A89-5B79BE236B02Q35750016-B7D5BD58-A158-41ED-8203-71B40952C3EEQ35775811-3AFC1C23-8F9B-4403-981C-B4BC2CCF2DC5Q37900313-6496069D-273F-4CFE-8773-95A01E8F25EBQ39021693-102605E1-F6AA-4617-B437-16CA585C2EC4Q45839998-348BDDE9-E6D8-42AF-A738-C2707243D656Q49350900-11E13D37-53D5-496E-8401-504DE3621062Q50519861-E338AB2C-4DDA-460C-982E-F0151A57C8DB
P2860
Modified dsRNAs that are not processed by Dicer maintain potency and are incorporated into the RISC
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Modified dsRNAs that are not p ...... are incorporated into the RISC
@ast
Modified dsRNAs that are not p ...... are incorporated into the RISC
@en
Modified dsRNAs that are not p ...... are incorporated into the RISC
@nl
type
label
Modified dsRNAs that are not p ...... are incorporated into the RISC
@ast
Modified dsRNAs that are not p ...... are incorporated into the RISC
@en
Modified dsRNAs that are not p ...... are incorporated into the RISC
@nl
prefLabel
Modified dsRNAs that are not p ...... are incorporated into the RISC
@ast
Modified dsRNAs that are not p ...... are incorporated into the RISC
@en
Modified dsRNAs that are not p ...... are incorporated into the RISC
@nl
P2093
P2860
P356
P1476
Modified dsRNAs that are not p ...... are incorporated into the RISC
@en
P2093
Jennifer Lapierre
Karen Bulock
Pamela Pavco
William Salomon
P2860
P304
P356
10.1093/NAR/GKQ055
P407
P577
2010-02-18T00:00:00Z