Recent advances in the protocols of transgenic mouse mutation assays.
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Mutagenicity testing with transgenic mice. Part I: Comparison with the mouse bone marrow micronucleus testMutagenicity testing with transgenic mice. Part II: Comparison with the mouse spot testAlterations in the mutagenicity and mutation spectrum induced by benzo[a]pyrene instilled in the lungs of gpt delta mice of various agesTransgenic rat models for mutagenesis and carcinogenesisIntegration of in vivo genotoxicity and short-term carcinogenicity assays using F344 gpt delta transgenic rats: in vivo mutagenicity of 2,4-diaminotoluene and 2,6-diaminotoluene structural isomers.Validation study of the combined repeated-dose toxicity and genotoxicity assay using gpt delta rats.Molecular nature of intrachromosomal deletions and base substitutions induced by environmental mutagens.Genetically engineered mouse models in cancer researchDevelopment of a Medium-term Animal Model Using gpt Delta Rats to Evaluate Chemical Carcinogenicity and Genotoxicity.Integrated one- and two-photon imaging platform reveals clonal expansion as a major driver of mutation load.Estimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta miceGenotoxicity of nano/microparticles in in vitro micronuclei, in vivo comet and mutation assay systems.Absence of in vivo mutagenicity of multi-walled carbon nanotubes in single intratracheal instillation study using F344 gpt delta rats.Magnetite Nanoparticles Induce Genotoxicity in the Lungs of Mice via Inflammatory Response.Tumor-augmenting effects of gestational arsenic exposure on F1 and F2 in mice.A strategy to study genotoxicity: application to aquatic toxins, limits and solutions.Fluorescence-Based Reporters for Detection of Mutagenesis in E. coli.Lack of genotoxic mechanisms in early-stage furan-induced hepatocellular tumorigenesis in gpt delta rats.Mutations in the lungs of gpt delta transgenic mice following inhalation of diesel exhaust.MX, a by-product of water chlorination, lacks in vivo genotoxicity in gpt delta mice but inhibits gap junctional intercellular communication in rat WB cells.Characterization of mutant spectra generated by a forward mutational assay for gene A of Phi X174 from ENU-treated transgenic mouse embryonic cell line PX-2.Cobalt nanoparticles induce lung injury, DNA damage and mutations in mice.Induction of lacZ mutations in MutaMouse primary hepatocytes.Role of p53 in the progression from ochratoxin A-induced DNA damage to gene mutations in the kidneys of mice.Evaluation of in vivo genotoxicity induced by N-ethyl-N-nitrosourea, benzo[a]pyrene, and 4-nitroquinoline-1-oxide in the Pig-a and gpt assays.Flumequine enhances the in vivo mutagenicity of MeIQx in the mouse liver.In vivo genotoxicity of methyleugenol in gpt delta transgenic rats following medium-term exposure.Oxidative DNA damage and in vivo mutagenicity caused by reactive oxygen species generated in the livers of p53-proficient or -deficient gpt delta mice treated with non-genotoxic hepatocarcinogens.Possible involvement of genotoxic mechanisms in estragole-induced hepatocarcinogenesis in rats.ATF4-dependent oxidative induction of the DNA repair enzyme Ape1 counteracts arsenite cytotoxicity and suppresses arsenite-mediated mutagenesis.Oxidative DNA damage and reporter gene mutation in the livers of gpt delta rats given non-genotoxic hepatocarcinogens with cytochrome P450-inducible potency.In vivo mutational analysis of liver DNA in gpt delta transgenic rats treated with the hepatocarcinogens N-nitrosopyrrolidine, 2-amino-3-methylimidazo[4,5-f]quinoline, and di(2-ethylhexyl)phthalate.In vivo mutagenesis induced by benzo[a]pyrene instilled into the lung of gpt delta transgenic mice.Combined application of comprehensive analysis for DNA modification and reporter gene mutation assay to evaluate kidneys of gpt delta rats given madder color or its constituents.Single-cell immunohistochemical mutation load assay (SCIMLA) using human paraffin-embedded tissues.Quantitative dose-response analysis of ethyl methanesulfonate genotoxicity in adult gpt-delta transgenic mice.In vivo mutagenesis in the lungs of gpt-delta transgenic mice treated intratracheally with 1,6-dinitropyrene.Construction of a supF-based system for detection of mutations in the chromosomal DNA of Arabidopsis.Glycosylphosphatidylinositol (GPI) anchored protein deficiency serves as a reliable reporter of Pig-a gene Mutation: Support from an in vitro assay based on L5178Y/Tk+/- cells and the CD90.2 antigen.Tissue-specific and time-dependent clonal expansion of ENU-induced mutant cells in gpt delta mice.
P2860
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P2860
Recent advances in the protocols of transgenic mouse mutation assays.
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2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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Recent advances in the protocols of transgenic mouse mutation assays.
@ast
Recent advances in the protocols of transgenic mouse mutation assays.
@en
Recent advances in the protocols of transgenic mouse mutation assays.
@nl
type
label
Recent advances in the protocols of transgenic mouse mutation assays.
@ast
Recent advances in the protocols of transgenic mouse mutation assays.
@en
Recent advances in the protocols of transgenic mouse mutation assays.
@nl
prefLabel
Recent advances in the protocols of transgenic mouse mutation assays.
@ast
Recent advances in the protocols of transgenic mouse mutation assays.
@en
Recent advances in the protocols of transgenic mouse mutation assays.
@nl
P1433
P1476
Recent advances in the protocols of transgenic mouse mutation assays
@en
P2093
P304
P356
10.1016/S0027-5107(00)00077-4
P407
P577
2000-11-01T00:00:00Z