Molecular mechanism of neurodegeneration induced by Alzheimer's beta-amyloid protein: channel formation and disruption of calcium homeostasis.
about
Calcium channel blockers and Alzheimer's diseaseAmyloid beta: multiple mechanisms of toxicity and only some protective effects?CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell deathModels of membrane-bound Alzheimer's Abeta peptide assembliesMechanisms underlying basal and learning-related intrinsic excitability in a mouse model of Alzheimer's disease.Models of beta-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process.Structure-function relationships of pre-fibrillar protein assemblies in Alzheimer's disease and related disordersSimultaneous single-molecule fluorescence and conductivity studies reveal distinct classes of Abeta species on lipid bilayersStructural convergence among diverse, toxic beta-sheet ion channels.Early calcium dysregulation in Alzheimer's disease: setting the stage for synaptic dysfunction.Effect of synthetic aβ peptide oligomers and fluorinated solvents on Kv1.3 channel properties and membrane conductance.Alzheimer's disease and Abeta toxicity: from top to bottom.Physicochemical characteristics of soluble oligomeric Abeta and their pathologic role in Alzheimer's disease.Neurodegeneration in glaucoma: progression and calcium-dependent intracellular mechanisms.Cadmium-induced apoptosis in primary rat cerebral cortical neurons culture is mediated by a calcium signaling pathway.Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network.Membrane Incorporation, Channel Formation, and Disruption of Calcium Homeostasis by Alzheimer's β-Amyloid Protein.Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease.Tau facilitates Aβ-induced loss of mitochondrial membrane potential independent of cytosolic calcium fluxes in mouse cortical neuronsStorage solutions: treating lysosomal disorders of the brain.Probing ion channel activity of human islet amyloid polypeptide (amylin).Neurosteroids block the increase in intracellular calcium level induced by Alzheimer’s β-amyloid protein in long-term cultured rat hippocampal neurons.The pathogenesis of Alzheimers disease is it a lifelong "calciumopathy"?Soluble amyloid beta-oligomers affect dielectric membrane properties by bilayer insertion and domain formation: implications for cell toxicityModels of toxic beta-sheet channels of protegrin-1 suggest a common subunit organization motif shared with toxic alzheimer beta-amyloid ion channels.Alterations of some membrane transport proteins in Alzheimer's disease: role of amyloid beta-peptide.Significant structural but not physiological changes in cortical neurons of 12-month-old Tg2576 mice.Effect of four medicinal plants on amyloid-β induced neurotoxicity in SH-SY5Y cells.Early Cytoskeletal Protein Modifications Precede Overt Structural Degeneration in the DBA/2J Mouse Model of Glaucoma.Oxidative stress and neurodegenerative disordersCognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling.Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channelsCalcium dyshomeostasis and neurotoxicity of Alzheimer's beta-amyloid protein.Non-selective ion channel activity of polymorphic human islet amyloid polypeptide (amylin) double channels.Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia.The Function of the Mitochondrial Calcium Uniporter in Neurodegenerative Disorders.Rare individual amyloid-β oligomers act on astrocytes to initiate neuronal damage.Neurodegeneration in familial amyloidotic polyneuropathy.Taurine and central nervous system disorders.Disruption of zinc homeostasis and the pathogenesis of senile dementia.
P2860
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P2860
Molecular mechanism of neurodegeneration induced by Alzheimer's beta-amyloid protein: channel formation and disruption of calcium homeostasis.
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
name
Molecular mechanism of neurode ...... uption of calcium homeostasis.
@ast
Molecular mechanism of neurode ...... uption of calcium homeostasis.
@en
Molecular mechanism of neurode ...... uption of calcium homeostasis.
@nl
type
label
Molecular mechanism of neurode ...... uption of calcium homeostasis.
@ast
Molecular mechanism of neurode ...... uption of calcium homeostasis.
@en
Molecular mechanism of neurode ...... uption of calcium homeostasis.
@nl
prefLabel
Molecular mechanism of neurode ...... uption of calcium homeostasis.
@ast
Molecular mechanism of neurode ...... uption of calcium homeostasis.
@en
Molecular mechanism of neurode ...... uption of calcium homeostasis.
@nl
P1476
Molecular mechanism of neurode ...... uption of calcium homeostasis.
@en
P2093
P304
P356
10.1016/S0361-9230(00)00370-1
P577
2000-11-01T00:00:00Z