Oligomerization of CD4 is required for stable binding to class II major histocompatibility complex proteins but not for interaction with human immunodeficiency virus gp120.
about
CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristicsIdentification of a proline-binding motif regulating CD2-triggered T lymphocyte activationCrystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC moleculeCharacterization of the major histocompatibility complex class II binding site on LAG-3 proteinLymphocyte-activation gene-3, an important immune checkpoint in cancerDirect evidence for native CD4 oligomers in lymphoid and monocytoid cells.Disulfide reduction in CD4 domain 1 or 2 is essential for interaction with HIV glycoprotein 120 (gp120), which impairs thioredoxin-driven CD4 dimerizationThe MHC class II ligand lymphocyte activation gene-3 is co-distributed with CD8 and CD3-TCR molecules after their engagement by mAb or peptide-MHC class I complexes.Engineered single human CD4 domains as potent HIV-1 inhibitors and components of vaccine immunogensMultivalent structure of an alphabetaT cell receptor.Exceptionally potent and broadly cross-reactive, bispecific multivalent HIV-1 inhibitors based on single human CD4 and antibody domains.CD46 short consensus repeats III and IV enhance measles virus binding but impair soluble hemagglutinin bindingThe two membrane proximal domains of CD4 interact with the T cell receptor.The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands.HLA class I and II antigens are partially co-clustered in the plasma membrane of human lymphoblastoid cells.Role of human CD4 D1D2 domain in HIV-1 infection.Second-messenger regulation of receptor association with clathrin-coated pits: a novel and selective mechanism in the control of CD4 endocytosis.Marked differences in the structures and protein associations of lymphocyte and monocyte CD4: resolution of a novel CD4 isoform.Efficient CD4 binding and immunosuppressive properties of the 13B8.2 monoclonal antibody are displayed by its CDR-H1-derived peptide CB1.A novel system for convenient detection of low-affinity receptor-ligand interactions: chelator-lipid liposomes engrafted with recombinant CD4 bind to cells expressing MHC class II.Identification of a human CD4-CDR3-like surface involved in CD4+ T cell function.Immunoglobulin superfamily proteins: structure, mechanisms, and drug discovery.T Cell Receptor Binding to a pMHCII Ligand Is Kinetically Distinct from and Independent of CD4.CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse.Signaling and functional properties of interleukin-16.Transduction of Activation Signal That Follows HIV-1 Binding to CD4 and CD4 Dimerization Involves the Immunoglobulin CDR3-like Region in Domain 1 of CD4
P2860
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P2860
Oligomerization of CD4 is required for stable binding to class II major histocompatibility complex proteins but not for interaction with human immunodeficiency virus gp120.
description
1995 nî lūn-bûn
@nan
1995 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
name
Oligomerization of CD4 is requ ...... immunodeficiency virus gp120.
@ast
Oligomerization of CD4 is requ ...... immunodeficiency virus gp120.
@en
Oligomerization of CD4 is requ ...... immunodeficiency virus gp120.
@nl
type
label
Oligomerization of CD4 is requ ...... immunodeficiency virus gp120.
@ast
Oligomerization of CD4 is requ ...... immunodeficiency virus gp120.
@en
Oligomerization of CD4 is requ ...... immunodeficiency virus gp120.
@nl
prefLabel
Oligomerization of CD4 is requ ...... immunodeficiency virus gp120.
@ast
Oligomerization of CD4 is requ ...... immunodeficiency virus gp120.
@en
Oligomerization of CD4 is requ ...... immunodeficiency virus gp120.
@nl
P2093
P2860
P356
P1476
Oligomerization of CD4 is requ ...... immunodeficiency virus gp120.
@en
P2093
E L Reinherz
T Sakihama
P2860
P304
P356
10.1073/PNAS.92.14.6444
P407
P577
1995-07-01T00:00:00Z