The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis. - Wikidata - wikimedia - TriplyDB

The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.

The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.

http://www.wikidata.org/entity/Q34246027

about

Emerging role of Hippo pathway in gastric and other gastrointestinal cancers A Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue Sarcomas Cadherin signaling: keeping cells in touch The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling.YAP and TAZ: a nexus for Hippo signaling and beyond Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer Regulation of localization and function of the transcriptional co-activator YAP by angiomotin.Commitment of Scaffold Proteins in the Onco-Biology of Human Colorectal Cancer and Liver Metastases after Oxaliplatin-Based Chemotherapy Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.Angiomotin Family Members: Oncogenes or Tumor Suppressors?Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma The role of angiomotin phosphorylation in the Hippo pathway during preimplantation mouse development.The hippo pathway in heart development, regeneration, and diseases YAP regulates S-phase entry in endothelial cells Angiomotin functions in HIV-1 assembly and budding.YAP promotes ovarian cancer cell tumorigenesis and is indicative of a poor prognosis for ovarian cancer patients.Disease implications of the Hippo/YAP pathway.Hippo signaling pathway in liver and pancreas: the potential drug target for tumor therapy.Endosomal regulation of contact inhibition through the AMOT:YAP pathway.Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish.Role of Merlin/NF2 inactivation in tumor biology.Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition.AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin Angiomotin promotes renal epithelial and carcinoma cell proliferation by retaining the nuclear YAP.LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.Angiomotin stabilization by tankyrase inhibitors antagonizes constitutive TEAD-dependent transcription and proliferation of human tumor cells with Hippo pathway core component mutations PKCι regulates nuclear YAP1 localization and ovarian cancer tumorigenesis Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth.Angiomotin'g YAP into the nucleus for cell proliferation and cancer development.The Angiomotins--from discovery to function.Molecular insights into NF2/Merlin tumor suppressor function.The Hippo signaling pathway in liver regeneration and tumorigenesis.Hippo signaling in epithelial stem cells.The anti-hepatic fibrosis effects of dihydrotanshinone I are mediated by disrupting the yes-associated protein and transcriptional enhancer factor D2 complex and stimulating autophagy.Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis.MicroRNA-497 inhibits cell proliferation, migration, and invasion by targeting AMOT in human osteosarcoma cells Angiomotin decreases lung cancer progression by sequestering oncogenic YAP/TAZ and decreasing Cyr61 expression.The roles of HOXD10 in the development and progression of head and neck squamous cell carcinoma (HNSCC).

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P2860

The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.

http://www.wikidata.org/entity/Q34246027

description

2013 nî lūn-bûn

@nan

2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

The p130 isoform of angiomotin ...... oliferation and tumorigenesis.

@ast

The p130 isoform of angiomotin ...... oliferation and tumorigenesis.

@en

The p130 isoform of angiomotin ...... oliferation and tumorigenesis.

@nl

type

label

The p130 isoform of angiomotin ...... oliferation and tumorigenesis.

@ast

The p130 isoform of angiomotin ...... oliferation and tumorigenesis.

@en

The p130 isoform of angiomotin ...... oliferation and tumorigenesis.

@nl

prefLabel

The p130 isoform of angiomotin ...... oliferation and tumorigenesis.

@ast

The p130 isoform of angiomotin ...... oliferation and tumorigenesis.

@en

The p130 isoform of angiomotin ...... oliferation and tumorigenesis.

@nl

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SCISIGNAL.2004060

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Science Signaling

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The p130 isoform of angiomotin ...... oliferation and tumorigenesis.

@en

P2093

Akihiko Shimono

http://www.w3.org/2001/XMLSchema#string

Anat Stemmer-Rachamimov

http://www.w3.org/2001/XMLSchema#string

Ben Z Stanger

http://www.w3.org/2001/XMLSchema#string

Chunling Yi

http://www.w3.org/2001/XMLSchema#string

Joseph L Kissil

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Lars Holmgren

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Louise C Showe

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Marius Sudol

http://www.w3.org/2001/XMLSchema#string

Noor Dawany

http://www.w3.org/2001/XMLSchema#string

Qin Liu

http://www.w3.org/2001/XMLSchema#string

P2860

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions

Angiomotin regulates endothelial cell-cell junctions and cell motility

Defining the human deubiquitinating enzyme interaction landscape

Angiomotin-like proteins associate with and negatively regulate YAP1

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

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10.1126/SCISIGNAL.2004060

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291

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6

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