Peroxisome proliferator-activated receptor {delta} is an essential transcriptional regulator for mitochondrial protection and biogenesis in adult heart
about
PPARs: Protectors or Opponents of Myocardial Function?Resveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1Exploring uncoupling proteins and antioxidant mechanisms under acute cold exposure in brains of fish.Perturbation of NCOA6 leads to dilated cardiomyopathy.Conditional PPARγ knockout from cardiomyocytes of adult mice impairs myocardial fatty acid utilization and cardiac function.Rosiglitazone causes cardiotoxicity via peroxisome proliferator-activated receptor γ-independent mitochondrial oxidative stress in mouse heartsPeroxisome proliferator-activated receptor δ agonist, HPP593, prevents renal necrosis under chronic ischemia.Aging influences cardiac mitochondrial gene expression and cardiovascular function following hemorrhage injury.Cardiomyocyte-Restricted Deletion of PPARβ/δ in PPARα-Null Mice Causes Impaired Mitochondrial Biogenesis and Defense, but No Further Depression of Myocardial Fatty Acid OxidationIntegrative and systemic approaches for evaluating PPARβ/δ (PPARD) function.Maintaining ancient organelles: mitochondrial biogenesis and maturation.A murine model of isolated cardiac steatosis leads to cardiomyopathy.Peroxisome proliferator-activated receptor β/δ activation in adult hearts facilitates mitochondrial function and cardiac performance under pressure-overload conditionVentricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failureMitochondrial dysfunction and activation of iNOS are responsible for the palmitate-induced decrease in adiponectin synthesis in 3T3L1 adipocytes.Activation of PPARδ prevents endothelial dysfunction induced by overexpression of amyloid-β precursor protein.Live cell screening platform identifies PPARδ as a regulator of cardiomyocyte proliferation and cardiac repairPerturbations in the gene regulatory pathways controlling mitochondrial energy production in the failing heart.Peroxisome proliferator activated receptor α ligands as anticancer drugs targeting mitochondrial metabolismPeroxisome-proliferator-activated receptors regulate redox signaling in the cardiovascular systemExposure to environmentally persistent free radicals during gestation lowers energy expenditure and impairs skeletal muscle mitochondrial function in adult mice.Size-dependent cytotoxicity of Fe3O4 nanoparticles induced by biphasic regulation of oxidative stress in different human hepatoma cellsAssessing Cardiac Metabolism: A Scientific Statement From the American Heart Association.Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-δ gene.Stromal interaction molecule 1 is essential for normal cardiac homeostasis through modulation of ER and mitochondrial function.PPARs as therapeutic targets in cardiovascular disease.The impact of current and novel anti-diabetic therapies on cardiovascular risk.Role of Pleiotropic Properties of Peroxisome Proliferator-Activated Receptors in the Heart: Focus on the Nonmetabolic Effects in Cardiac Protection.Cardiac nuclear receptors: architects of mitochondrial structure and function.A comprehensive review of the bioenergetics of fatty acid and glucose metabolism in the healthy and failing heart in nondiabetic condition.Knockout of the ATPase inhibitory factor 1 protects the heart from pressure overload-induced cardiac hypertrophy.Honokiol protects against doxorubicin cardiotoxicity via improving mitochondrial function in mouse hearts.Regulating PPARδ signaling as a potential therapeutic strategy for skeletal muscle disorders in heart failure.The Implication of PGC-1α on Fatty Acid Transport across Plasma and Mitochondrial Membranes in the Insulin Sensitive Tissues.Telmisartan modulates mitochondrial function in vascular smooth muscle cells.Manifestations and mechanisms of myocardial lipotoxicity in obesity.Cardiomyocyte-Restricted Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Deletion Leads to Lethal Dilated Cardiomyopathy Partly Through Drp1 Signaling.PPAR-delta promotes survival of chronic lymphocytic leukemia cells in energetically unfavorable conditions.Piper retrofractum Vahl. Extract, as a PPARδ and AMPK Activator, Suppresses UVB-Induced Photoaging through Mitochondrial Biogenesis and MMPs Inhibition in Human Dermal Fibroblasts and Hairless Mice.A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways
P2860
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P2860
Peroxisome proliferator-activated receptor {delta} is an essential transcriptional regulator for mitochondrial protection and biogenesis in adult heart
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Peroxisome proliferator-activa ...... and biogenesis in adult heart
@ast
Peroxisome proliferator-activa ...... and biogenesis in adult heart
@en
Peroxisome proliferator-activa ...... and biogenesis in adult heart
@nl
type
label
Peroxisome proliferator-activa ...... and biogenesis in adult heart
@ast
Peroxisome proliferator-activa ...... and biogenesis in adult heart
@en
Peroxisome proliferator-activa ...... and biogenesis in adult heart
@nl
prefLabel
Peroxisome proliferator-activa ...... and biogenesis in adult heart
@ast
Peroxisome proliferator-activa ...... and biogenesis in adult heart
@en
Peroxisome proliferator-activa ...... and biogenesis in adult heart
@nl
P2093
P2860
P1433
P1476
Peroxisome proliferator-activa ...... and biogenesis in adult heart
@en
P2093
Jinwen Luo
John Chatham
Olga Zhelyabovska
Peiyong Wang
Qinglin Yang
P2860
P304
P356
10.1161/CIRCRESAHA.109.206185
P577
2010-01-14T00:00:00Z