Activation of D1/D5 dopamine receptors protects neurons from synapse dysfunction induced by amyloid-beta oligomers
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Alzheimer's disease and insulin resistance: translating basic science into clinical applicationsAmyloid-β oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neuronsDopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease.Pharmacokinetics and dopamine/acetylcholine releasing effects of ginsenoside Re in hippocampus and mPFC of freely moving rats.d-serine levels in Alzheimer's disease: implications for novel biomarker developmentAlzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.Soluble oligomers of amyloid-β peptide disrupt membrane trafficking of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor contributing to early synapse dysfunction.The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease.Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's diseaseCarriers of a common variant in the dopamine transporter gene have greater dementia risk, cognitive decline, and faster ventricular expansion.Amyloid-β oligomers induce differential gene expression in adult human brain slices.Partial depletion of striatal dopamine enhances penetrance of cognitive deficits in a transgenic mouse model of Alzheimer's disease.Inhibition of choline acetyltransferase as a mechanism for cholinergic dysfunction induced by amyloid-β peptide oligomers.L-Stepholidine rescues memory deficit and synaptic plasticity in models of Alzheimer's disease via activating dopamine D1 receptor/PKA signaling pathway.Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.Protein Tyrosine Phosphatase 1B (PTP1B): A Potential Target for Alzheimer's Therapy?Dopamine D1/D5 receptors mediate informational saliency that promotes persistent hippocampal long-term plasticityDeregulation of excitatory neurotransmission underlying synapse failure in Alzheimer's disease.Linking insulin with Alzheimer's disease: emergence as type III diabetes.Posttranslational modification impact on the mechanism by which amyloid-β induces synaptic dysfunction.USP46: a new piece of the memory puzzle?Amyloid-β oligomers transiently inhibit AMP-activated kinase and cause metabolic defects in hippocampal neurons.Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice.The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease.Synaptotoxic Signaling by Amyloid Beta Oligomers in Alzheimer's Disease Through Prion Protein and mGluR5.Challenges for Alzheimer's Disease Therapy: Insights from Novel Mechanisms Beyond Memory Defects.Critical review: involvement of endoplasmic reticulum stress in the aetiology of Alzheimer's disease.
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P2860
Activation of D1/D5 dopamine receptors protects neurons from synapse dysfunction induced by amyloid-beta oligomers
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Activation of D1/D5 dopamine r ...... uced by amyloid-beta oligomers
@ast
Activation of D1/D5 dopamine r ...... uced by amyloid-beta oligomers
@en
Activation of D1/D5 dopamine r ...... uced by amyloid-beta oligomers
@nl
type
label
Activation of D1/D5 dopamine r ...... uced by amyloid-beta oligomers
@ast
Activation of D1/D5 dopamine r ...... uced by amyloid-beta oligomers
@en
Activation of D1/D5 dopamine r ...... uced by amyloid-beta oligomers
@nl
prefLabel
Activation of D1/D5 dopamine r ...... uced by amyloid-beta oligomers
@ast
Activation of D1/D5 dopamine r ...... uced by amyloid-beta oligomers
@en
Activation of D1/D5 dopamine r ...... uced by amyloid-beta oligomers
@nl
P2093
P2860
P356
P1476
Activation of D1/D5 dopamine r ...... uced by amyloid-beta oligomers
@en
P2093
Emilio R Garrido-Sanabria
Fernanda G De Felice
Gabriela E A Mussi
Jordano Brito-Moreira
Leandro L Antonio
Sergio T Ferreira
Sofia Jürgensen
Theresa R Bomfim
Ésper A Cavalheiro
P2860
P304
P356
10.1074/JBC.M110.177790
P407
P577
2010-11-29T00:00:00Z