about
Design and pre-clinical evaluation of a universal HIV-1 vaccineHIV CTL escape: at what cost?Inefficient cytotoxic T lymphocyte-mediated killing of HIV-1-infected cells in vivoAnalysis of 'driver' and 'passenger' CD8+ T-cell responses against variable virusesStructural consequences of target epitope-directed functional alteration of an antibody. The case of anti-hen lysozyme antibody, HyHEL-10DNA vaccines against human immunodeficiency virus type 1.De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infectionEpitope mapping of HIV-specific CD8+ T cell responses by multiple immunological readouts reveals distinct specificities defined by function.Human immunodeficiency virus type 1 superinfection was not detected following 215 years of injection drug user exposure.CD4+ T cell depletion in human immunodeficiency virus (HIV) infection: role of apoptosis.Adoptive therapy with CD8(+) T cells: it may get by with a little help from its friendsEnhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences.The many important facets of T-cell repertoire diversity.Effective T-cell responses select human immunodeficiency virus mutants and slow disease progression.Human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T(EMRA) cells in early infection are linked to control of HIV-1 viremia and predict the subsequent viral load set pointConflicting selection pressures on T-cell epitopes in HIV-1 subtype B.Growth hormone enhances thymic function in HIV-1-infected adultsHIV-specific CD8⁺ T cells and HIV eradicationProtective 'immunity' by pre-existent neutralizing antibody titers and preactivated T cells but not by so-called 'immunological memory'.Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitopeImmune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte response in an HLA-B27-positive long-term-nonprogressing child.A dual color ELISPOT method for the simultaneous detection of IL-2 and IFN-gamma HIV-specific immune responses.Extraepitopic compensatory substitutions partially restore fitness to simian immunodeficiency virus variants that escape from an immunodominant cytotoxic-T-lymphocyte responseConsistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities.HLA-associated clinical progression correlates with epitope reversion rates in early human immunodeficiency virus infectionSTEP trial and HIV-1 vaccines inducing T-cell responses.Rationale for the design of an oncology trial using a generic targeted therapy multi‑drug regimen for NSCLC patients without treatment options (Review)Discovery of novel targets for multi-epitope vaccines: screening of HIV-1 genomes using association rule mining.Prolonged transcriptional silencing and CpG methylation induced by siRNAs targeted to the HIV-1 promoter region.Diversity of escape variant mutations in Simian virus 40 large tumor antigen (SV40 Tag) epitopes selected by cytotoxic T lymphocyte (CTL) clones.Promoter Targeting shRNA Suppresses HIV-1 Infection In vivo Through Transcriptional Gene Silencing.Between-host evolution of cytotoxic T-lymphocyte epitopes in human immunodeficiency virus type 1: an approach based on phylogenetically independent comparisons.CD8+ T-cell-mediated cross-clade protection in the genital tract following intranasal immunization with inactivated human immunodeficiency virus antigen plus CpG oligodeoxynucleotides.Selective induction of CTL helper rather than killer activity by natural epitope variants promotes dendritic cell-mediated HIV-1 dissemination.Decreased frequency of CD73+CD8+ T cells of HIV-infected patients correlates with immune activation and T cell exhaustion.Do antiviral CD8+ T cells select hepatitis C virus escape mutants? Analysis in diverse epitopes targeted by human intrahepatic CD8+ T lymphocytes.Analysis of the relationship between cytokine secretion and proliferative capacity in hepatitis C virus infection.Complex positive selection pressures drive the evolution of HIV-1 with different co-receptor tropisms.An in vivo replication-important function in the second coding exon of Tat is constrained against mutation despite cytotoxic T lymphocyte selection.Bad news for stop–start therapy?
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
HIV: current opinion in escapology.
@ast
HIV: current opinion in escapology.
@en
HIV: current opinion in escapology.
@nl
type
label
HIV: current opinion in escapology.
@ast
HIV: current opinion in escapology.
@en
HIV: current opinion in escapology.
@nl
prefLabel
HIV: current opinion in escapology.
@ast
HIV: current opinion in escapology.
@en
HIV: current opinion in escapology.
@nl
P1476
HIV: current opinion in escapology.
@en
P2093
Rodney Phillips
P304
P356
10.1016/S1369-5274(02)00339-9
P577
2002-08-01T00:00:00Z