A novel pan-negative-gating modulator of KCa2/3 channels, fluoro-di-benzoate, RA-2, inhibits endothelium-derived hyperpolarization-type relaxation in coronary artery and produces bradycardia in vivo.
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Pharmacological gating modulation of small- and intermediate-conductance Ca(2+)-activated K(+) channels (KCa2.x and KCa3.1)Down-regulation of KCa2.3 channels causes erectile dysfunction in miceInhibition of Intermediate-Conductance Calcium-Activated K Channel (KCa3.1) and Fibroblast Mitogenesis by α-Linolenic Acid and Alterations of Channel Expression in the Lysosomal Storage Disorders, Fabry Disease, and Niemann Pick CSK4 K+ channels are therapeutic targets for the treatment of cardiac arrhythmiasEmerging roles of calcium-activated K channels and TRPV4 channels in lung oedema and pulmonary circulatory collapse.Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed.Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes.
P2860
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P2860
A novel pan-negative-gating modulator of KCa2/3 channels, fluoro-di-benzoate, RA-2, inhibits endothelium-derived hyperpolarization-type relaxation in coronary artery and produces bradycardia in vivo.
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A novel pan-negative-gating mo ...... produces bradycardia in vivo.
@ast
A novel pan-negative-gating mo ...... produces bradycardia in vivo.
@en
A novel pan-negative-gating mo ...... produces bradycardia in vivo.
@nl
type
label
A novel pan-negative-gating mo ...... produces bradycardia in vivo.
@ast
A novel pan-negative-gating mo ...... produces bradycardia in vivo.
@en
A novel pan-negative-gating mo ...... produces bradycardia in vivo.
@nl
prefLabel
A novel pan-negative-gating mo ...... produces bradycardia in vivo.
@ast
A novel pan-negative-gating mo ...... produces bradycardia in vivo.
@en
A novel pan-negative-gating mo ...... produces bradycardia in vivo.
@nl
P2093
P2860
P50
P356
P1476
A novel pan-negative-gating mo ...... produces bradycardia in vivo.
@en
P2093
Brandon M Brown
Celia Laría
Heike Wulff
José A Gálvez
María Divina Murillo
Nicole Coleman
Ralf Köhler
P2860
P304
P356
10.1124/MOL.114.095745
P577
2014-12-02T00:00:00Z