Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus.
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Inosine monophosphate dehydrogenase expression and activity are significantly lower in kidney transplant recipients with diabetes mellitus.Pharmacokinetics of total and unbound prednisone and prednisolone in stable kidney transplant recipients with diabetes mellitus.Concentration of tacrolimus and major metabolites in kidney transplant recipients as a function of diabetes mellitus and cytochrome P450 3A gene polymorphism.Suppression of the pregnane X receptor during endoplasmic reticulum stress is achieved by down-regulating hepatocyte nuclear factor-4α and up-regulating liver-enriched inhibitory protein.No impact of vitamin D on the CYP3A biomarker 4β-hydroxycholesterol in patients with abnormal glucose regulation.Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null miceThe Promises of Quantitative Proteomics in Precision MedicineEffect of diabetes mellitus on pharmacokinetic and pharmacodynamic properties of drugs.Role of microRNAs in the regulation of drug metabolism and disposition genes in diabetes and liver disease.Pharmacokinetic considerations in chronic kidney disease and patients requiring dialysis.CYP3A activity: towards dose adaptation to the individual.Clinical Pharmacokinetics and Pharmacodynamics of Antihyperglycemic Medications in Children and Adolescents with Type 2 Diabetes Mellitus.Non-alcoholic fatty liver disease (NAFLD) - pathogenesis, classification, and effect on drug metabolizing enzymes and transporters.Cyp3a11-mediated testosterone-6β-hydroxylation decreased, while UGT1a9-mediated propofol O-glucuronidation increased, in mice with diabetes mellitus.Rapid and accurate liquid chromatography and tandem mass spectrometry method for the simultaneous quantification of ten metabolic reactions catalyzed by hepatic cytochrome P450 enzymes.Modulation of CYP3a expression and activity in mice models of type 1 and type 2 diabetes.Tissue Specific Modulation of cyp2c and cyp3a mRNA Levels and Activities by Diet-Induced Obesity in Mice: The Impact of Type 2 Diabetes on Drug Metabolizing Enzymes in Liver and Extra-Hepatic Tissues.Aspartame Administration and Insulin Treatment Altered Brain Levels of CYP2E1 and CYP3A2 in Streptozotocin-Induced Diabetic Rats.Long-term expression of glomerular genes in diabetic nephropathy.Difference in the Pharmacokinetics and Hepatic Metabolism of Antidiabetic Drugs in Zucker Diabetic Fatty and Sprague-Dawley Rats.Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1α/Stra13 pathway.Alterations in the gene expression of drug and arachidonic acid-metabolizing Cyp450 in the livers of controlled and uncontrolled insulin-dependent diabetic mice
P2860
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P2860
Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Significantly reduced cytochro ...... humans with diabetes mellitus.
@ast
Significantly reduced cytochro ...... humans with diabetes mellitus.
@en
type
label
Significantly reduced cytochro ...... humans with diabetes mellitus.
@ast
Significantly reduced cytochro ...... humans with diabetes mellitus.
@en
prefLabel
Significantly reduced cytochro ...... humans with diabetes mellitus.
@ast
Significantly reduced cytochro ...... humans with diabetes mellitus.
@en
P2093
P2860
P1476
Significantly reduced cytochro ...... humans with diabetes mellitus.
@en
P2093
Bingfang Yan
Fatemeh Akhlaghi
Michael H Court
Miroslav Dostalek
P2860
P304
P356
10.1111/J.1476-5381.2011.01270.X
P407
P577
2011-07-01T00:00:00Z