The histone methyltransferase Smyd2 is a negative regulator of macrophage activation by suppressing interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) production
about
Epigenetic Control of Macrophage Polarisation and Soluble Mediator Gene Expression during InflammationHistone methyltransferases: novel targets for tumor and developmental defectsChemical probes targeting epigenetic proteins: Applications beyond oncology.Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer.SMYD proteins in immunity: dawning of a new era.Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.Epigenetic modifications of interleukin-6 in synovial fibroblasts from osteoarthritis patientsInhibitors of Protein Methyltransferases and Demethylases.Epigenetic Regulation of Monocyte and Macrophage Function.H3K36 methyltransferases as cancer drug targets: rationale and perspectives for inhibitor developmentArsenic alters global histone modifications in lymphocytes in vitro and in vivo.Promising landscape for regulating macrophage polarization: epigenetic viewpointSmyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis.IL-34 Suppresses Candida albicans Induced TNFα Production in M1 Macrophages by Downregulating Expression of Dectin-1 and TLR2.Macrophage polarization and allergic asthma.The lysine methyltransferase SMYD2 methylates the kinase domain of type II receptor BMPR2 and stimulates bone morphogenetic protein signaling.SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells.Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation.Epigenetic control of macrophage polarization: implications for targeting tumor-associated macrophages.SMYD2 glutathionylation contributes to degradation of sarcomeric proteinsEpigenetics in Cardiac Fibrosis: Emphasis on Inflammation and Fibroblast Activation
P2860
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P2860
The histone methyltransferase Smyd2 is a negative regulator of macrophage activation by suppressing interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) production
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
The histone methyltransferase ...... is factor α (TNF-α) production
@ast
The histone methyltransferase ...... is factor α (TNF-α) production
@en
type
label
The histone methyltransferase ...... is factor α (TNF-α) production
@ast
The histone methyltransferase ...... is factor α (TNF-α) production
@en
prefLabel
The histone methyltransferase ...... is factor α (TNF-α) production
@ast
The histone methyltransferase ...... is factor α (TNF-α) production
@en
P2093
P2860
P356
P1476
The histone methyltransferase ...... is factor α (TNF-α) production
@en
P2093
Biao Zheng
Guiliang Xu
Guilin Liu
Haiyan Liu
Sidong Xiong
P2860
P304
P356
10.1074/JBC.M114.610345
P407
P577
2015-01-12T00:00:00Z