Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise. - Wikidata - wikimedia - TriplyDB

Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise.

Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise.

http://www.wikidata.org/entity/Q35167221

about

Chromatin features and the epigenetic regulation of pluripotency states in ESCs Retroviral transcriptional regulation and embryonic stem cells: war and peace What obesity research tells us about epigenetic mechanisms DNA methylation, its mediators and genome integrity The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration TRIM28 is required by the mouse KRAB domain protein ZFP568 to control convergent extension and morphogenesis of extra-embryonic tissues Transcriptome profiling of liver of non-genetic low birth weight and long term health consequences.Differential regulation of the α-globin locus by Krüppel-like Factor 3 in erythroid and non-erythroid cells.An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse Transcriptional regulators TRIM28, SETDB1, and TP53 are aberrantly expressed in porcine embryos produced by in vitro fertilization in comparison to in vivo- and somatic-cell nuclear transfer-derived embryos Expression of MAS1 in breast cancer.Early-Onset Paternal Smoking and Offspring Adiposity: Further Investigation of a Potential Intergenerational Effect Using the HUNT Study.Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity.Maternally provided LSD1/KDM1A enables the maternal-to-zygotic transition and prevents defects that manifest postnatally.Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype.A molecular mechanism for therapeutic effects of cGMP-elevating agents in pulmonary arterial hypertension.Liver-specific ablation of Krüppel-associated box-associated protein 1 in mice leads to male-predominant hepatosteatosis and development of liver adenoma.The use of mouse models to study epigenetics The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis.Metabolic heterogeneity of activated beige/brite adipocytes in inguinal adipose tissue.The epigenetic modifier Fam208a is required to maintain epiblast cell fitness.The role of human endogenous retroviruses in brain development and function.Position-effect variegation revisited: HUSHing up heterochromatin in human cells.TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells.Panel sequencing of 264 candidate susceptibility genes and segregation analysis in a cohort of non-BRCA1, non-BRCA2 breast cancer families.Regulated noise in the epigenetic landscape of development and disease.A forward genetic screen identifies eukaryotic translation initiation factor 3, subunit H (eIF3h), as an enhancer of variegation in the mouse.Oxidative stress signaling to chromatin in health and disease.Apoptosis and DNA methylation.Within-strain variation in behavior differs consistently between common inbred strains of mice.Chromatin modifications in metabolic disease: Potential mediators of long-term disease risk.Trim28 is required for epigenetic stability during mouse oocyte to embryo transition.No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations.Epigenetic control of variation and stochasticity in metabolic disease.HebbPlot: an intelligent tool for learning and visualizing chromatin mark signatures

P2860

Q26860693-29A1858A-1CA4-4EA8-83C5-2BA74AFDD54C Q26865715-230475A1-74F1-4B00-9335-FFB623B55741 Q27008101-24A46DE5-6B54-430D-8B10-173DD3782322 Q28080760-DB95C0DC-4EC9-48A4-B22F-64CD0131BA0D Q28512405-077A8891-044B-4103-AD4E-D4142F70A5F7 Q28513391-9A67809D-BE17-418B-AD3B-D1A44A437868 Q31162094-00953347-8F2D-46B4-A8F0-FC67F58D7FB9 Q33662656-BC7996DF-CA8D-4047-8CDE-B47A464F601B Q33742092-E5E2DD52-66F1-4BCF-A92B-CA1470DA358A Q34531622-DC3BF42F-F01B-470B-9FFA-CDACE52167D4 Q36092905-BE97DEF2-2106-4C90-AAC9-4B2334FA4FD1 Q36211873-E43470E2-78E2-467E-8814-3288CBE0252A Q36526377-4C7101ED-5260-468E-9D98-CE1B407E0D03 Q36791936-55050251-1DB6-4791-8284-96C03099A4E3 Q36835644-DEC88F4F-1FA7-4174-8C67-2C48EA400E98 Q36910085-6BCE8DE7-326D-4290-A148-4BDAB42E9490 Q36972688-75B0F51E-3754-4393-8122-EB295B65F97A Q37258705-623C619A-76D9-4E9F-BDB2-153C26C92D08 Q37546071-D5435141-FFB4-4151-99B5-994C21FB33C4 Q37550272-B41F2268-67CD-4FC5-B66A-45E3B46A75C3 Q38609407-18C63CAB-BA71-4FB2-97B4-A89985C2BE48 Q38714227-5EF96EE7-F76C-4797-9A62-BA95B0F7BE22 Q38725574-0920DE2B-7988-4192-8D40-15B44629E50C Q39067871-FB85E81C-5E91-4F8F-8079-0B1967853266 Q40070779-CE606811-42CF-4997-AB32-DEC0B0BFB41F Q41514448-48141712-C3DD-4296-B9C0-6E5536F8DF42 Q41620760-B19930F5-0552-4F57-BD59-0B1EF115B892 Q42123491-D133D497-B2E9-463F-B3F6-6B861B026DA5 Q42576933-EB92CDB9-0876-4DBD-944C-A614AA7C44DB Q46707609-9FE4C836-859D-4F45-8D60-DFB43D15F70C Q47712510-CB4C8C7D-66F1-419E-9056-C99661B198B2 Q48652732-DC17E90B-85CC-4A4A-AAF9-288B927EDCE5 Q51026043-DEA9D524-7E8A-4048-BA63-3F9580B411E2 Q55506430-3546B373-933F-4A06-98EA-6BA7970DF8AA Q58768540-FED4A196-8216-410E-AC6A-B231A085E01C

P2860

Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise.

http://www.wikidata.org/entity/Q35167221

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Reduced levels of two modifier ...... se increased phenotypic noise.

@ast

Reduced levels of two modifier ...... se increased phenotypic noise.

@en

type

label

Reduced levels of two modifier ...... se increased phenotypic noise.

@ast

Reduced levels of two modifier ...... se increased phenotypic noise.

@en

prefLabel

Reduced levels of two modifier ...... se increased phenotypic noise.

@ast

Reduced levels of two modifier ...... se increased phenotypic noise.

@en

P1433

Q35167221-35DA26ED-E5B3-492F-B161-27D37642DC41

P1476

Q35167221-6B55F85A-3004-4243-8867-327869E63C7B

P2093

Q35167221-1D6C9F86-81B3-4EA1-9A5A-4A88F802139F

Q35167221-2BACF44C-7D93-4511-9488-42DDB911D967

Q35167221-407DB7AA-AB64-42A0-A017-2744F4ED7019

Q35167221-50145802-15D5-40D2-8323-39C3EEE587F2

Q35167221-9F996496-28BE-49B8-B47A-3C31D53803A4

Q35167221-A1BFAEF7-EFA5-4261-AD67-4A7183E419E8

Q35167221-A9DD19AB-A417-4C0F-AED7-BDC4918545E9

Q35167221-D29D474A-5816-4C8B-B6E9-F062240176D2

Q35167221-EC5BC4B0-2209-4066-BD75-BDB7BAEBE3BD

P2860

Q35167221-0C8A2317-A2CF-4432-9A6C-575E3A520CD3

Q35167221-0F7B0BF7-3D21-4300-ACD9-46965EF14518

Q35167221-1745AF29-956B-4186-ACBE-79BFFB1239AC

Q35167221-230D38B9-36AA-4F24-ACF1-0D35CDBF1CF6

Q35167221-320CE65A-FFFF-47D8-80C3-C27D58FC71F7

Q35167221-337332F0-7C84-4B0D-9DF2-954FFFF6C7C2

Q35167221-3F9A2754-E17B-42AE-9103-06CBF2198D7B

Q35167221-4275AD08-2383-4B98-A165-54EAD31E408E

Q35167221-45D461CC-F3D9-48C2-BB7E-17AD335FDA9C

Q35167221-496F865D-5969-4C42-8C2B-782602F1F3F4

P2888

Q35167221-1F431DB5-2432-490C-9AF0-E71490DA327C

P304

Q35167221-FAF49EE6-6EC9-4A35-9E9F-20DD9661354A

P31

Q35167221-13465445-DB7E-4FA9-B158-3A2178252BD7

P356

Q35167221-2BF4B380-ABB9-4C48-9D12-A372C700D687

P433

Q35167221-DD5A70E1-FBEE-4F03-8CCB-DA207ADFC967

P478

Q35167221-C7A514CD-7A03-46A8-B8C0-37F28AE01026

P577

Q35167221-56EEA11B-8F5D-4658-BEC8-1970E9CD1287

P5875

Q35167221-CF4FAE68-F587-4ED6-B3F8-5E657A21DF51

P6179

Q35167221-78478970-5A38-4566-8235-6C71A697B5A6

P698

Q35167221-1BA229AD-D80F-4C5F-A4BD-4663CFF7D66B

P921

Q35167221-5B04E7B6-C860-42A8-9D4D-37EB83227C00

P932

Q35167221-0DCDEAA6-4229-473E-9F0E-6F9E05E16523

P356

GB-2010-11-11-R111

P1433

P1476

Reduced levels of two modifier ...... se increased phenotypic noise.

@en

P2093

Alyson Ashe

http://www.w3.org/2001/XMLSchema#string

Colm Nestor

http://www.w3.org/2001/XMLSchema#string

Daniel K Morgan

http://www.w3.org/2001/XMLSchema#string

Eleanore Lambley

http://www.w3.org/2001/XMLSchema#string

Emma Whitelaw

http://www.w3.org/2001/XMLSchema#string

Nadia C Whitelaw

http://www.w3.org/2001/XMLSchema#string

Richard Meehan

http://www.w3.org/2001/XMLSchema#string

Suyinn Chong

http://www.w3.org/2001/XMLSchema#string

Timothy J Bruxner

http://www.w3.org/2001/XMLSchema#string

P2860

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

Obesity: Genetic, molecular, and environmental aspects

Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation

Control of stochasticity in eukaryotic gene expression

Noise in eukaryotic gene expression

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

P2888

gb-2010-11-11-r111

P304

R111

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1186/GB-2010-11-11-R111

http://www.w3.org/2001/XMLSchema#string

P433

11

http://www.w3.org/2001/XMLSchema#string

P478

11

http://www.w3.org/2001/XMLSchema#string

P577

2010-11-19T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49623358

http://www.w3.org/2001/XMLSchema#string

P6179

1019371462

http://www.w3.org/2001/XMLSchema#string

P698

21092094

http://www.w3.org/2001/XMLSchema#string

P921

P932

3156950

http://www.w3.org/2001/XMLSchema#string