Assessing helical protein interfaces for inhibitor design. - Wikidata - wikimedia - TriplyDB

Assessing helical protein interfaces for inhibitor design.

Assessing helical protein interfaces for inhibitor design.

http://www.wikidata.org/entity/Q35201483

about

Synthetic Peptides as Protein Mimics Multi-Facial, Non-Peptidic α-Helix Mimetics Adding diverse noncanonical backbones to rosetta: enabling peptidomimetic design Differential Impact of β and γ Residue Preorganization on α/β/γ-Peptide Helix Stability in Water Enhancement of α-Helix Mimicry by an α/β-Peptide Foldamer via Incorporation of a Dense Ionic Side-Chain Array Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies A Strategy for Direct Chemical Activation of the Retinoblastoma Protein Serverification of molecular modeling applications: the Rosetta Online Server that Includes Everyone (ROSIE)Structure-based inhibition of protein-protein interactions.Protein-Protein Interactions Mediated by Helical Tertiary Structure Motifs.Truncated and helix-constrained peptides with high affinity and specificity for the cFos coiled-coil of AP-1 Comparative α-helicity of cyclic pentapeptides in water.Helix Nucleation by the Smallest Known α-Helix in Water.In vivo modulation of hypoxia-inducible signaling by topographical helix mimetics.Large ring-forming alkylations provide facile access to composite macrocycles Essential multimeric enzymes in kinetoplastid parasites: A host of potentially druggable protein-protein interactions.Anatomy of β-strands at protein-protein interfaces.A leap into the chemical space of protein-protein interaction inhibitors Comprehensive peptidomimetic libraries targeting protein-protein interactions.Downsizing a human inflammatory protein to a small molecule with equal potency and functionality.Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.Plucking the high hanging fruit: a systematic approach for targeting protein-protein interactions Design of libraries targeting protein-protein interfaces.Solid-phase methodology for synthesis of O-alkylated aromatic oligoamide inhibitors of α-helix-mediated protein-protein interactions Computational analysis of protein-protein interfaces involving an alpha helix: insights for terphenyl-like molecules binding.Rational design of topographical helix mimics as potent inhibitors of protein-protein interactions.Understanding the molecular basis of EGFR kinase domain/MIG-6 peptide recognition complex using computational analyses Selective and potent proteomimetic inhibitors of intracellular protein-protein interactions Human immunodeficiency virus-associated dementia: a link between accumulation of viral proteins and neuronal degeneration.State-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.Towards more drug-like proteomimetics: two-faced, synthetic α-helix mimetics based on a purine scaffold.High-resolution structures of a heterochiral coiled coil Identification of a binding site of the human immunodeficiency virus envelope protein gp120 to neuronal-specific tubulin Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling.HippDB: a database of readily targeted helical protein-protein interactions.Functional, metal-based crosslinkers for α-helix induction in short peptides Design, synthesis, conformational analysis and application of indolizidin-2-one dipeptide mimics.Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics.Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes.The Pseudomonas aeruginosa AmrZ C-terminal domain mediates tetramerization and is required for its activator and repressor functions

P2860

Q26770255-D8FFF2B0-2D6E-4F3B-B56E-6EBEBDF69310 Q26781261-8F776967-D714-4BBD-BC0E-AE45CF582933 Q27312673-D08CBD22-0736-4EA4-8764-40C0FBAC09C1 Q27678274-E0D8EC72-84BC-45C6-B598-8E5B5689AC80 Q27678660-6D5FEBCE-3FAC-46EB-92A9-E9647AD5106D Q27701444-87CA294A-125C-413B-B52F-71CD243DCB13 Q28820981-6E98B760-4C6D-4674-BECE-4CB456A74BED Q28914729-64BC7F50-2AD8-4EAB-8BCB-B977B3116078 Q30367145-79FC5565-967F-4B20-9636-C5FE7302DF3F Q30378305-C6EB7F23-67ED-404B-B5FC-C3CFF9E08C7D Q30610173-F9703383-A64B-4271-88D6-BEACBA20258E Q30820760-E635D3F7-9B68-4C9E-9BDE-295A53511881 Q31102104-91CFB119-5D60-437F-BE75-E8BE88CCF4FC Q33694597-6F055F78-D3D4-4496-8B94-FC6BD305DFDE Q33836980-A062EBCF-7594-4B7D-A4C0-1F72B37D75BD Q33898663-56F0B106-DB8A-484F-B7B0-45A61CC7AD4C Q34061140-323E8267-3BDA-4311-8510-C945368AFC33 Q34287849-78D23A74-DBDC-4F3D-B09E-E4259A6925E9 Q34338569-2F25F120-7060-4259-8ED1-7C4D961E8AA3 Q34386483-3F1DB11C-A5C5-4D04-8566-4B89D3D6D12A Q34481459-65D33D52-C21C-4A12-92DC-1E23A299DFE1 Q34522767-0733B91D-0DC0-4412-863F-562618AB86FA Q34597781-A045AD65-3DA1-4D25-8336-CF93171E380C Q34627084-97822327-D97B-4137-A040-4F31B0C94B84 Q34773950-2443752C-5C50-4B17-A0FC-2A556F502848 Q35157579-F9C3F658-A7C4-40F8-AB3F-BCAA8ADBA8A0 Q35247477-9726B023-CC6C-4839-B30B-B2BA13EE9B39 Q35555133-45DE1873-4510-49D0-BD24-DFDE4EFEEEA2 Q35702700-A5B3E493-86D6-4BD5-A504-0791B3DFAC89 Q35738960-46057117-8D68-4B83-B742-DB76011040C8 Q35926303-9634A7ED-7DCB-4B70-BD03-973CCCF9CD30 Q36238386-5733ED54-6273-4B3E-9948-FDCF8A9983DB Q36788754-D9F33799-09C5-4300-9B3B-D28044CA824C Q37203888-14F130F0-96A3-4A7B-AFBB-2A21F1B0B0AA Q37236866-854A67DF-AA86-4D90-916F-11D40900FDEF Q37239938-FA1F2095-349D-49DA-B80D-E2BD81250C0B Q38217773-FF454B41-04BB-4782-9E87-395073F832C6 Q38253734-E3728072-DAFB-4CA0-B56C-7DDA33AD8BEA Q38539666-60048609-3A6A-451A-A6CE-34771B83D73E Q38661016-CADB4930-E1EC-46C7-BC4B-FB2B853A803C

P2860

Assessing helical protein interfaces for inhibitor design.

http://www.wikidata.org/entity/Q35201483

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Assessing helical protein interfaces for inhibitor design.

@ast

Assessing helical protein interfaces for inhibitor design.

@en

type

label

Assessing helical protein interfaces for inhibitor design.

@ast

Assessing helical protein interfaces for inhibitor design.

@en

prefLabel

Assessing helical protein interfaces for inhibitor design.

@ast

Assessing helical protein interfaces for inhibitor design.

@en

P1433

Q35201483-232B7945-2CCB-4038-8748-200B6E977755

P1476

Q35201483-CF3A32A7-263C-45D0-AA7B-ACEF1A79E438

P2093

Q35201483-172BD86A-80AB-4A31-9697-39D12EBBC44C

Q35201483-4CB5F109-384A-4641-926B-1C88DA79A810

Q35201483-83E7C435-A2E7-4170-93D7-7DED15C577B3

P2860

Q35201483-01EDA6EB-D07A-4F1B-BB39-08A9C140226E

Q35201483-046D6991-E02B-4EC1-B1AA-CCD1677652F1

Q35201483-0B71325C-FF0C-4504-BD27-8FBB48DB1FF7

Q35201483-0EB0568B-CF10-4D35-B4AE-F297DE7338C5

Q35201483-169A6350-E52F-4150-B546-BD0734786255

Q35201483-18D836D3-9E65-4622-9231-8ACA44B6654C

Q35201483-1C43ED14-D6F3-481C-BBAF-76C4A5413B13

Q35201483-2A197D36-3F09-4503-8C66-6ED8630ACFF5

Q35201483-2A355236-E89C-4B92-8206-5CF8A442488B

Q35201483-2DFD455D-AF81-4584-B7B9-79E86BA2422C

P304

Q35201483-3A15B113-F54E-4132-B90F-0CC24A518AD0

P31

Q35201483-1C48DB44-5358-4115-A6D7-6BA8A8019F56

P356

Q35201483-46716C7C-3F7A-476C-A47B-59A70C48290F

P407

Q35201483-F0E528B3-D70D-4C1B-99C7-41F3A5F66AAE

P433

Q35201483-86C39DFE-7489-488D-9BE1-5E3DAC613197

P478

Q35201483-DAEFB623-17B3-4232-94F0-D6C5677CCDC6

P577

Q35201483-DA90C0A0-D553-4E78-8F23-BD5C9EE6FC67

P5875

Q35201483-165D5A00-14BF-4346-B028-D08C01A51343

P698

Q35201483-2CB61EBD-BD4F-4EA2-A901-65D3F132214D

P921

Q35201483-4BD9DE70-5BA4-4F41-B1D6-D61D00C1ED97

P932

Q35201483-74E5EA2B-5856-45E9-BE36-7083586E4F42

P356

P1433

Journal of the American Chemical Society

P1476

Assessing helical protein interfaces for inhibitor design.

@en

P2093

Andrea L Jochim

http://www.w3.org/2001/XMLSchema#string

Brooke N Bullock

http://www.w3.org/2001/XMLSchema#string

Paramjit S Arora

http://www.w3.org/2001/XMLSchema#string

P2860

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.

Systematic analysis of helical protein interfaces reveals targets for synthetic inhibitors

Direct inhibition of the NOTCH transcription factor complex

Structural and biological mimicry of protein surface recognition by / -peptide foldamers

The atomic structure of protein-protein recognition sites

Foldamers as versatile frameworks for the design and evolution of function

A simple physical model for binding energy hot spots in protein-protein complexes

A hot spot of binding energy in a hormone-receptor interface

Anatomy of hot spots in protein interfaces

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

P304

14220-14223

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/JA206074J

http://www.w3.org/2001/XMLSchema#string

P407

P433

36

http://www.w3.org/2001/XMLSchema#string

P478

133

http://www.w3.org/2001/XMLSchema#string

P577

2011-08-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51575607

http://www.w3.org/2001/XMLSchema#string

P698

21846146

http://www.w3.org/2001/XMLSchema#string

P921

P932

3168723

http://www.w3.org/2001/XMLSchema#string