Interspecies scaling of receptor-mediated pharmacokinetics and pharmacodynamics of type I interferons.
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Agonistic TAM-163 antibody targeting tyrosine kinase receptor-B: applying mechanistic modeling to enable preclinical to clinical translation and guide clinical trial designProjecting human pharmacokinetics of monoclonal antibodies from nonclinical data: comparative evaluation of prediction approaches in early drug development.Interspecies scaling and prediction of human clearance: comparison of small- and macro-molecule drugsQuantitative prediction of human pharmacokinetics for mAbs exhibiting target-mediated disposition.Target-mediated pharmacokinetic and pharmacodynamic model of exendin-4 in rats, monkeys, and humansPharmacokinetics and toxicology of therapeutic proteins: Advances and challenges.Physiologically-based pharmacokinetic modeling of target-mediated drug disposition of bortezomib in mice.Bridging Clinical Outcomes of Canakinumab Treatment in Patients With Rheumatoid Arthritis With a Population Model of IL-1β Kinetics.Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta CellsBridging the species divide: transgenic mice humanized for type-I interferon response.The pharmacokinetic/pharmacodynamic pipeline: translating anticancer drug pharmacology to the clinic.Monoclonal antibodies: what are the pharmacokinetic and pharmacodynamic considerations for drug development?Tools for predicting the PK/PD of therapeutic proteins.Characterization and Interspecies Scaling of rhTNF-α Pharmacokinetics with Minimal Physiologically Based Pharmacokinetic Models.Prospective Design of Anti-Transferrin Receptor Bispecific Antibodies for Optimal Delivery into the Human Brain.A Tutorial on Target-Mediated Drug Disposition (TMDD) Models.Interspecies pharmacokinetic modeling of subcutaneous absorption of rituximab in mice and rats.Interspecies modeling and prediction of human exenatide pharmacokineticsPrediction of a Therapeutic Dose for Buagafuran, a Potent Anxiolytic Agent by Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Starting from Pharmacokinetics in Rats and Human.Sustained plasma hepcidin suppression and iron elevation by Anticalin-derived hepcidin antagonist in cynomolgus monkey.Quantitative prediction of human pharmacokinetics for monoclonal antibodies: retrospective analysis of monkey as a single species for first-in-human prediction.Polypharmacology modelling using proteochemometrics (PCM): recent methodological developments, applications to target families, and future prospects
P2860
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P2860
Interspecies scaling of receptor-mediated pharmacokinetics and pharmacodynamics of type I interferons.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Interspecies scaling of recept ...... ynamics of type I interferons.
@ast
Interspecies scaling of recept ...... ynamics of type I interferons.
@en
type
label
Interspecies scaling of recept ...... ynamics of type I interferons.
@ast
Interspecies scaling of recept ...... ynamics of type I interferons.
@en
prefLabel
Interspecies scaling of recept ...... ynamics of type I interferons.
@ast
Interspecies scaling of recept ...... ynamics of type I interferons.
@en
P2093
P2860
P1476
Interspecies scaling of recept ...... ynamics of type I interferons.
@en
P2093
Anson K Abraham
Donald E Mager
John M Harrold
Leonid Kagan
P2860
P304
P356
10.1007/S11095-010-0098-6
P577
2010-03-16T00:00:00Z