mTOR inhibition induces compensatory, therapeutically targetable MEK activation in renal cell carcinoma.
about
The selective MEK1 inhibitor Selumetinib enhances the antitumor activity of everolimus against renal cell carcinoma in vitro and in vivo.Synergistic roles of p53 and HIF1α in human renal cell carcinoma-cell apoptosis responding to the inhibition of mTOR and MDM2 signaling pathways.Synergistic targeted inhibition of MEK and dual PI3K/mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma.MiR-144 inhibits cell proliferation of renal cell carcinoma by targeting MTOR.Resveratrol Potentiates Growth Inhibitory Effects of Rapamycin in PTEN-deficient Lipoma Cells by Suppressing p70S6 Kinase Activity.The epidermal growth factor receptor pathway in chronic kidney diseases.Prognostic value of copper transporter 1 expression in patients with clear cell renal cell carcinoma.Naturally Occurring Canine Melanoma as a Predictive Comparative Oncology Model for Human Mucosal and Other Triple Wild-Type Melanomas.RAPTOR up-regulation contributes to resistance of renal cancer cells to PI3K-mTOR inhibition.
P2860
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P2860
mTOR inhibition induces compensatory, therapeutically targetable MEK activation in renal cell carcinoma.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
mTOR inhibition induces compen ...... ation in renal cell carcinoma.
@ast
mTOR inhibition induces compen ...... ation in renal cell carcinoma.
@en
type
label
mTOR inhibition induces compen ...... ation in renal cell carcinoma.
@ast
mTOR inhibition induces compen ...... ation in renal cell carcinoma.
@en
prefLabel
mTOR inhibition induces compen ...... ation in renal cell carcinoma.
@ast
mTOR inhibition induces compen ...... ation in renal cell carcinoma.
@en
P2093
P2860
P1433
P1476
mTOR inhibition induces compen ...... ation in renal cell carcinoma.
@en
P2093
Aleisha M Smith
Bhavani Krishnan
Harper L Wilson
Jeffrey S Damrauer
Jen Jen Yeh
Mingqing Li
Sean T Bailey
William Y Kim
P2860
P304
P356
10.1371/JOURNAL.PONE.0104413
P407
P577
2014-09-02T00:00:00Z