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Intravascular flow decreases erythrocyte consumption of nitric oxide.

Intravascular flow decreases erythrocyte consumption of nitric oxide.

http://www.wikidata.org/entity/Q35564207

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Cytoglobin is expressed in the vasculature and regulates cell respiration and proliferation via nitric oxide dioxygenation Sequestration of extracellular hemoglobin within a haptoglobin complex decreases its hypertensive and oxidative effects in dogs and guinea pigs The chemical biology of S-nitrosothiols Exercise and NO production: relevance and implications in the cardiopulmonary system Hemoglobin-mediated nitric oxide signaling Research opportunities in optimizing storage of red blood cell products Application of a nitric oxide sensor in biomedicine The shaping of nitric oxide signals by a cellular sink Endothelial nitric oxide synthase in the microcirculation.Relationship of cell-free hemoglobin to impaired endothelial nitric oxide bioavailability and perfusion in severe falciparum malaria Effect of erythrocyte aggregation and flow rate on cell-free layer formation in arterioles.Modulation of nitric oxide bioavailability by erythrocytes.Plasma nitrite rather than nitrate reflects regional endothelial nitric oxide synthase activity but lacks intrinsic vasodilator action.Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions.Nitric oxide reaction with red blood cells and hemoglobin under heterogeneous conditions Nitric oxide is consumed, rather than conserved, by reaction with oxyhemoglobin under physiological conditions.Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin.Interactions of nitric oxide-derived reactive nitrogen species with peroxidases and lipoxygenases.Oxidative mechanisms of hemoglobin-based blood substitutes.The biological lifetime of nitric oxide: implications for the perivascular dynamics of NO and O2.Inhibition of human platelet aggregation by a novel S-nitrosothiol is abolished by haemoglobin and red blood cells in vitro: implications for anti-thrombotic therapy Computation of plasma hemoglobin nitric oxide scavenging in hemolytic anemias.Mechanisms of slower nitric oxide uptake by red blood cells and other hemoglobin-containing vesicles.Nitric oxide transport in normal human thoracic aorta: effects of hemodynamics and nitric oxide scavengers.Pathological basis of symptoms and crises in sickle cell disorder: implications for counseling and psychotherapy Role of 20-HETE in the pial arteriolar constrictor response to decreased hematocrit after exchange transfusion of cell-free polymeric hemoglobin Dependence of acetylcholine and ADP dilation of pial arterioles on heme oxygenase after transfusion of cell-free polymeric hemoglobin.Toxicities of hemoglobin solutions: in search of in-vitro and in-vivo model systems.Low micromolar intravascular cell-free hemoglobin concentration affects vascular NO bioavailability in sickle cell disease: a computational analysis Nitrite and nitric oxide metabolism in peripheral artery disease.Hemoglobin-mediated, hypoxia-induced vasodilation via nitric oxide: mechanism(s) and physiologic versus pathophysiologic relevance.Effect of processing and storage on red blood cell function in vivo The Reactivity of Polymersome Encapsulated Hemoglobin with Physiologically Important Gaseous Ligands: Oxygen, Carbon Monoxide and Nitric Oxide.Nitric oxide transport in an axisymmetric stenosis Regulation of nitric oxide consumption by hypoxic red blood cells Lowering of blood pressure by increasing hematocrit with non nitric oxide scavenging red blood cells.Cardiopulmonary complications of sickle cell disease: role of nitric oxide and hemolytic anemia.Interactions of nitrosylhemoglobin and carboxyhemoglobin with erythrocyte.Catalytic consumption of nitric oxide by 12/15- lipoxygenase: inhibition of monocyte soluble guanylate cyclase activation The potential of Angeli's salt to decrease nitric oxide scavenging by plasma hemoglobin.

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P2860

Intravascular flow decreases erythrocyte consumption of nitric oxide.

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Intravascular flow decreases erythrocyte consumption of nitric oxide

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J C Liao

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L Kuo

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T W Hein

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P2860

Mechanism of NO-induced oxidation of myoglobin and hemoglobin

Role of endothelium-derived nitric oxide in the regulation of blood pressure

Effects of inhibition of nitric oxide formation on basal vasomotion and endothelium-dependent responses of the coronary arteries in awake dogs

Simulation of the diffusion and reaction of endogenously produced nitric oxide.

Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions.

Inhibition of neointimal proliferation in rabbits after vascular injury by a single treatment with a protein adduct of nitric oxide.

Modulation of platelet aggregation by an L-arginine-nitric oxide pathway.

Tetrahydrobiopterin, a cofactor for nitric oxide synthase, produces endothelium-dependent dilation of mouse pial arterioles.

Conformation, co-operativity and ligand binding in human hemoglobin.

The biological and pharmacological role of nitric oxide in platelet function.

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