The role of MHC class II molecules in susceptibility to type I diabetes: identification of peptide epitopes and characterization of the T cell repertoire
about
Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitusDouble negative (CD3+ 4- 8-) TCR alphabeta splenic cells from young NOD mice provide long-lasting protection against type 1 diabetesStructure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetesGenetics of type 1 diabetes mellitusGenetic-induced variations in the GAD65 T-cell repertoire governs efficacy of anti-CD3/GAD65 combination therapy in new-onset type 1 diabetes.Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cellsNew therapeutic approaches to type 1 diabetes: from prevention to cellular or gene therapies.Genetic basis of remitting sarcoidosis: triumph of the trimolecular complex?Specificity of peptide selection by antigen-presenting cells homozygous or heterozygous for expression of class II MHC molecules: The lack of competitionCentral and peripheral autoantigen presentation in immune tolerance.The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetesSusceptible MHC alleles, not background genes, select an autoimmune T cell reactivity.Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase.Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes.CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transferInnocuous IFNgamma induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 productionTranslational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes.Prophylactic and therapeutic suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor.Autoimmune type 1 diabetes genetic susceptibility encoded by human leukocyte antigen DRB1 and DQB1 genes in TunisiaPrevention of type 1 diabetes by gene therapy.Long-term silencing of autoimmune diabetes and improved life expectancy by a soluble pHLA-DR4 chimera in a newly-humanized NOD/DR4/B7 mouse.The role of HLA-DQ8 beta57 polymorphism in the anti-gluten T-cell response in coeliac disease.Influence on spontaneous tissue inflammation by the major histocompatibility complex region in the nonobese diabetic mouse.
P2860
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P2860
The role of MHC class II molecules in susceptibility to type I diabetes: identification of peptide epitopes and characterization of the T cell repertoire
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
The role of MHC class II molec ...... ation of the T cell repertoire
@ast
The role of MHC class II molec ...... ation of the T cell repertoire
@en
type
label
The role of MHC class II molec ...... ation of the T cell repertoire
@ast
The role of MHC class II molec ...... ation of the T cell repertoire
@en
prefLabel
The role of MHC class II molec ...... ation of the T cell repertoire
@ast
The role of MHC class II molec ...... ation of the T cell repertoire
@en
P2093
P2860
P356
P1476
The role of MHC class II molec ...... ation of the T cell repertoire
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.16.9299
P407
P577
1999-08-01T00:00:00Z