Aurora kinase inhibition overcomes cetuximab resistance in squamous cell cancer of the head and neck
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Aurora Kinases and Potential Medical Applications of Aurora Kinase Inhibitors: A ReviewScientific Rationale Supporting the Clinical Development Strategy for the Investigational Aurora A Kinase Inhibitor Alisertib in CancerCalmodulin protects Aurora B on the midbody to regulate the fidelity of cytokinesis.Selective Targeting of CTNBB1-, KRAS- or MYC-Driven Cell Growth by Combinations of Existing DrugsAurora kinases in head and neck cancerAurora kinases: novel therapy targets in cancersAurora-A signaling is activated in advanced stage of squamous cell carcinoma of head and neck cancer and requires osteopontin to stimulate invasive behavior.The quest to overcome resistance to EGFR-targeted therapies in cancer.Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation.Combined inhibition of Chk1 and Wee1: in vitro synergistic effect translates to tumor growth inhibition in vivo.Potential impact of human papilloma virus on survival of basaloid squamous carcinoma of the head and neck.A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer.A functional cooperativity between Aurora A kinase and LIM kinase1: implication in the mitotic processMetformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation.Depletion of Aurora A leads to upregulation of FoxO1 to induce cell cycle arrest in hepatocellular carcinoma cells.Dual EGFR inhibition in combination with anti-VEGF treatment: a phase I clinical trial in non-small cell lung cancerHypoxia induces TFE3 expression in head and neck squamous cell carcinomaAnti-epidermal growth factor receptor therapy in head and neck squamous cell carcinoma: focus on potential molecular mechanisms of drug resistanceThe response of head and neck squamous cell carcinoma to cetuximab treatment depends on Aurora kinase A polymorphism.Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition.Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation.Assessment of EGFR/HER2 dimerization by FRET-FLIM utilizing Alexa-conjugated secondary antibodies in relation to targeted therapies in cancers.Bronchogenic cancer: It still exists.The induction of polyploidy or apoptosis by the Aurora A kinase inhibitor MK8745 is p53-dependent.Biologic therapy in head and neck cancer: a road with hurdles.Design, synthesis and biological activity of N4-phenylsubstituted-7H-pyrrolo[2,3-d]pyrimidin-4-amines as dual inhibitors of aurora kinase A and epidermal growth factor receptor kinase.Deguelin, a Novel Anti-Tumorigenic Agent in Human Esophageal Squamous Cell Carcinoma.High NOTCH1 mRNA Expression Is Associated with Better Survival in HNSCC.
P2860
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P2860
Aurora kinase inhibition overcomes cetuximab resistance in squamous cell cancer of the head and neck
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Aurora kinase inhibition overc ...... ll cancer of the head and neck
@ast
Aurora kinase inhibition overc ...... ll cancer of the head and neck
@en
type
label
Aurora kinase inhibition overc ...... ll cancer of the head and neck
@ast
Aurora kinase inhibition overc ...... ll cancer of the head and neck
@en
prefLabel
Aurora kinase inhibition overc ...... ll cancer of the head and neck
@ast
Aurora kinase inhibition overc ...... ll cancer of the head and neck
@en
P2093
P2860
P356
P1433
P1476
Aurora kinase inhibition overc ...... ll cancer of the head and neck
@en
P2093
Alexander Hoellein
Anja Baumgart
Anja Pickhard
Christian Peschel
Fabienne von Keitz
Guido Piontek
Henning Bier
Martina Rudelius
Stefan Wagenpfeil
Stephanie Schoeffmann
P2860
P304
P356
10.18632/ONCOTARGET.311
P407
P577
2011-08-01T00:00:00Z