Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease. - Wikidata - wikimedia - TriplyDB

Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease.

Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease.

http://www.wikidata.org/entity/Q35752509

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Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke The Guanine nucleotide exchange factor kalirin-7 is a novel synphilin-1 interacting protein and modifies synphilin-1 aggregate transport and formation Validation study of genetic associations with coronary artery disease on chromosome 3q13-21 and potential effect modification by smoking Abnormal kalirin signaling in neuropsychiatric disorders.Rho GAPs and GEFs: controling switches in endothelial cell adhesion Small G proteins in the cardiovascular system: physiological and pathological aspects Kalrn plays key roles within and outside of the nervous system Kalirin promotes neointimal hyperplasia by activating Rac in smooth muscle cells Gene Expression Profiles Link Respiratory Viral Infection, Platelet Response to Aspirin, and Acute Myocardial Infarction Elimination of Kalrn expression in POMC cells reduces anxiety-like behavior and contextual fear learning.Polymorphic variants in tenascin-C (TNC) are associated with atherosclerosis and coronary artery disease.The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports Genetic and functional association of FAM5C with myocardial infarction Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis Using Kalirin conditional knockout mice to distinguish its role in dopamine receptor mediated behaviors Kalrn promoter usage and isoform expression respond to chronic cocaine exposure Genetic Variant of Kalirin Gene Is Associated with Ischemic Stroke in a Chinese Han Population.Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies.Fine mapping of a linkage peak with integration of lipid traits identifies novel coronary artery disease genes on chromosome 5 Genetic analysis of polymorphisms in the kalirin gene for association with age-at-onset in European Huntington disease patients.Identification of kalirin-7 as a potential post-synaptic density signaling hub Resequencing and association analysis of the KALRN and EPHB1 genes and their contribution to schizophrenia susceptibility.Case-Only Survival Analysis Reveals Unique Effects of Genotype, Sex, and Coronary Disease Severity on Survivorship.Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFβR3 In Vitro.Association of Roadway Proximity with Fasting Plasma Glucose and Metabolic Risk Factors for Cardiovascular Disease in a Cross-Sectional Study of Cardiac Catheterization Patients.Genetic and genomic insights into the molecular basis of atherosclerosis.A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience.The NEIGHBOR consortium primary open-angle glaucoma genome-wide association study: rationale, study design, and clinical variables An LRP8 variant is associated with familial and premature coronary artery disease and myocardial infarction.CdGAP/ARHGAP31, a Cdc42/Rac1 GTPase regulator, is critical for vascular development and VEGF-mediated angiogenesis.Polymorphisms of the tumor suppressor gene LSAMP are associated with left main coronary artery disease.The genetic basis for survivorship in coronary artery disease.Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events.Molecular signatures of cardiovascular disease risk: potential for test development and clinical application.Gene-smoking interactions in multiple Rho-GTPase pathway genes in an early-onset coronary artery disease cohort.Neuronal Rho GEFs in synaptic physiology and behavior.Nonenzymatic domains of Kalirin7 contribute to spine morphogenesis through interactions with phosphoinositides and Abl Kalirin signaling: implications for synaptic pathology.Kalirin, a key player in synapse formation, is implicated in human diseases.

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P2860

Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease.

http://www.wikidata.org/entity/Q35752509

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A Brent Hale

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Carol Haynes

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Christopher J H Jones

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Marco Harris

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Pascal J Goldschmidt-Clermont

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P2860

Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on chromosome 17

Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain

Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease.

Haploview: analysis and visualization of LD and haplotype maps

Gene variants of VAMP8 and HNRPUL1 are associated with early-onset myocardial infarction

Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho

Ropporin, a sperm-specific binding protein of rhophilin, that is localized in the fibrous sheath of sperm flagella

Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies

Mortality by cause for eight regions of the world: Global Burden of Disease Study

UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans.

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Jonathan L Haines

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