Both conserved region 1 (CR1) and CR2 of the human papillomavirus type 16 E7 oncogene are required for induction of epidermal hyperplasia and tumor formation in transgenic mice.
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Bovine papillomavirus E7 transformation function correlates with cellular p600 protein bindingThe E7 oncoprotein of human papillomavirus type 16 stabilizes p53 through a mechanism independent of p19(ARF).Critical roles for non-pRb targets of human papillomavirus type 16 E7 in cervical carcinogenesisThe human papillomavirus E6 oncogene dysregulates the cell cycle and contributes to cervical carcinogenesis through two independent activities.Immunohistochemical analysis, human papillomavirus DNA detection, hormonal manipulation, and exogenous gene expression of normal and dysplastic human cervical epithelium in severe combined immunodeficiency mice.The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals.Examination of the pRb-dependent and pRb-independent functions of E7 in vivo.Human papillomavirus type 16 E1circumflexE4 contributes to multiple facets of the papillomavirus life cycle.Interactions with pocket proteins contribute to the role of human papillomavirus type 16 E7 in the papillomavirus life cycle.Persistence of high-grade cervical dysplasia and cervical cancer requires the continuous expression of the human papillomavirus type 16 E7 oncogene.Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivoDominant role of HPV16 E7 in anal carcinogenesis.Human papillomavirus type 16 E6 and E7 oncogenes abrogate radiation-induced DNA damage responses in vivo through p53-dependent and p53-independent pathways.Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion.E7 oncoprotein of novel human papillomavirus type 108 lacking the E6 gene induces dysplasia in organotypic keratinocyte culturesThe papillomavirus E7 proteins.Oncogenic activities of human papillomaviruses.The human papillomavirus E7 oncoprotein.The human papillomavirus E7 oncoprotein as a regulator of transcription.Pocket proteins suppress head and neck cancer
P2860
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P2860
Both conserved region 1 (CR1) and CR2 of the human papillomavirus type 16 E7 oncogene are required for induction of epidermal hyperplasia and tumor formation in transgenic mice.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Both conserved region 1 (CR1) ...... formation in transgenic mice.
@ast
Both conserved region 1 (CR1) ...... formation in transgenic mice.
@en
type
label
Both conserved region 1 (CR1) ...... formation in transgenic mice.
@ast
Both conserved region 1 (CR1) ...... formation in transgenic mice.
@en
prefLabel
Both conserved region 1 (CR1) ...... formation in transgenic mice.
@ast
Both conserved region 1 (CR1) ...... formation in transgenic mice.
@en
P2093
P2860
P1433
P1476
Both conserved region 1 (CR1) ...... formation in transgenic mice.
@en
P2093
G A Gulliver
P F Lambert
R L Herber
P2860
P304
P407
P577
1997-08-01T00:00:00Z