B cell expression of the SH2-containing inositol 5-phosphatase (SHIP-1) is required to establish anergy to high affinity, proteinacious autoantigens.

B cell expression of the SH2-containing inositol 5-phosphatase (SHIP-1) is required to establish anergy to high affinity, proteinacious autoantigens.

Item
http://www.wikidata.org/entity/Q35930409
Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells.The Dok-3/Grb2 adaptor module promotes inducible association of the lipid phosphatase SHIP with the BCR in a coreceptor-independent manner.Regulation of immune cell signaling by SHIP1: A phosphatase, scaffold protein, and potential therapeutic target.Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway.SHIP-1 Deficiency in AID(+) B Cells Leads to the Impaired Function of B10 Cells with Spontaneous Autoimmunity.B-cell-intrinsic function of TAPP adaptors in controlling germinal center responses and autoantibody production in mice.Src Homology 2 Domain-Containing Inositol 5'-Phosphatase Ameliorates High Glucose-Induced Extracellular Matrix Deposition via the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway in Renal Tubular Epithelial Cells.Putting on the Brakes: Regulatory Kinases and Phosphatases Maintaining B Cell Anergy.
P2860

B cell expression of the SH2-containing inositol 5-phosphatase (SHIP-1) is required to establish anergy to high affinity, proteinacious autoantigens.

Item
http://www.wikidata.org/entity/Q35930409
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
B cell expression of the SH2-c ...... y, proteinacious autoantigens.
@ast
B cell expression of the SH2-c ...... y, proteinacious autoantigens.
@en
type
label
B cell expression of the SH2-c ...... y, proteinacious autoantigens.
@ast
B cell expression of the SH2-c ...... y, proteinacious autoantigens.
@en
prefLabel
B cell expression of the SH2-c ...... y, proteinacious autoantigens.
@ast
B cell expression of the SH2-c ...... y, proteinacious autoantigens.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P478
P50
P577
P698
P932
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B cell expression of the SH2-c ...... y, proteinacious autoantigens.
@en
P2093
P2860
P304
P31
P356
10.1016/J.JAUT.2015.06.007
P478
P50
P577
P698
P932