Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility - Wikidata - wikimedia - TriplyDB

Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility

Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility

http://www.wikidata.org/entity/Q35947508

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The mitochondria in diabetic heart failure: from pathogenesis to therapeutic promise How exercise may amend metabolic disturbances in diabetic cardiomyopathy Adaptive reciprocity of lipid and glucose metabolism in human short-term starvation Acylcarnitines: reflecting or inflicting insulin resistance?Adipose fatty acid oxidation is required for thermogenesis and potentiates oxidative stress-induced inflammation DNA methylation of oxidative stress genes and cancer risk in the Normative Aging Study Discovery of novel vitamin D-regulated proteins in INS-1 cells: a proteomic approach Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export Gut microbiota from twins discordant for obesity modulate metabolism in mice Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour Titin-truncating variants affect heart function in disease cohorts and the general population.Skeletal Muscle Nucleo-Mitochondrial Crosstalk in Obesity and Type 2 Diabetes.Muscle uncoupling protein 3 overexpression mimics endurance training and reduces circulating biomarkers of incomplete β-oxidation.Effects of acute physical exercise on oxidative stress and inflammatory status in young, sedentary obese subjects.Detection and Alterations of Acetylcarnitine in Human Skeletal Muscles by 1H MRS at 7 T.Altered nutrient response of mTORC1 as a result of changes in REDD1 expression: effect of obesity vs. REDD1 deficiency.Ketone bodies as signaling metabolites.Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness.Downregulation of carnitine acyl-carnitine translocase by miRNAs 132 and 212 amplifies glucose-stimulated insulin secretion The molecular and metabolic influence of long term agmatine consumption Nonalcoholic Fatty liver disease: pathogenesis and therapeutics from a mitochondria-centric perspective.Chemical-genetic induction of Malonyl-CoA decarboxylase in skeletal muscle.Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance.Regulation of substrate utilization by the mitochondrial pyruvate carrier Compartmentalized acyl-CoA metabolism in skeletal muscle regulates systemic glucose homeostasis Acylcarnitines: potential implications for skeletal muscle insulin resistance.Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection.Therapeutic effects of adropin on glucose tolerance and substrate utilization in diet-induced obese mice with insulin resistance.L-carnitine and PPARα-agonist fenofibrate are involved in the regulation of Carnitine Acetyltransferase (CrAT) mRNA levels in murine liver cells.Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardiovascular diseases: form and function.Multiple mass isotopomer tracing of acetyl-CoA metabolism in Langendorff-perfused rat hearts: channeling of acetyl-CoA from pyruvate dehydrogenase to carnitine acetyltransferase.β-hydroxybutyrate: much more than a metabolite Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training.Increased missense mutation burden of Fatty Acid metabolism related genes in nunavik inuit population.Drug Transporters and Na+/H+ Exchange Regulatory Factor PSD-95/Drosophila Discs Large/ZO-1 Proteins Lipid-induced mitochondrial stress and insulin action in muscle Perilipin 3 Differentially Regulates Skeletal Muscle Lipid Oxidation in Active, Sedentary, and Type 2 Diabetic Males Aberrant REDD1-mTORC1 responses to insulin in skeletal muscle from Type 2 diabetics Isoprenoid biosynthesis in dandelion latex is enhanced by the overexpression of three key enzymes involved in the mevalonate pathway

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P2860

Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility

http://www.wikidata.org/entity/Q35947508

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Muscle-specific deletion of ca ...... ance and metabolic flexibility

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Muscle-specific deletion of ca ...... ance and metabolic flexibility

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Muscle-specific deletion of ca ...... ance and metabolic flexibility

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Muscle-specific deletion of ca ...... ance and metabolic flexibility

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Muscle-specific deletion of ca ...... ance and metabolic flexibility

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Muscle-specific deletion of ca ...... ance and metabolic flexibility

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J.CMET.2012.04.005

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Cell Metabolism

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Muscle-specific deletion of ca ...... ance and metabolic flexibility

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Indu Kheterpal

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Jean-Paul Kovalik

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Jeffrey D Covington

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Jingying Zhang

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Karen L DeBalsi

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Michael N Davies

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Olga R Ilkayeva

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Randall L Mynatt

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Robert C Noland

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Robert D Stevens

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P2860

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

Purification and properties of carnitine acetyltransferase from human liver

Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

Redesign of carnitine acetyltransferase specificity by protein engineering

Evidence of a malonyl-CoA-insensitive carnitine palmitoyltransferase I activity in red skeletal muscle

Acetyl-L-carnitine infusion increases glucose disposal in type 2 diabetic patients.

L-carnitine improves glucose disposal in type 2 diabetic patients.

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764-777

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10.1016/J.CMET.2012.04.005

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5

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William E. Kraus

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2012-05-01T00:00:00Z

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224912772

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22560225

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3348515

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