NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment. - Wikidata - wikimedia - TriplyDB

NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.

NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.

http://www.wikidata.org/entity/Q36108861

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Specific NuRD components are required for fin regeneration in zebrafish Towards elucidating the stability, dynamics and architecture of the nucleosome remodeling and deacetylase complex by using quantitative interaction proteomics Embryonic stem cell and induced pluripotent stem cell: an epigenetic perspective Modifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in Disease Emerging Molecular and Biological Functions of MBD2, a Reader of DNA Methylation Common stemness regulators of embryonic and cancer stem cells Chromatin features and the epigenetic regulation of pluripotency states in ESCs Ex uno plures: molecular designs for embryonic pluripotency The NuRD architecture Retroviral transcriptional regulation and embryonic stem cells: war and peace MBD2 and MBD3: elusive functions and mechanisms The extended pluripotency protein interactome and its links to reprogramming NURDs are required for diversity Reprogramming of cell fate: epigenetic memory and the erasure of memories past The Nucleosome Remodeling and Deacetylase Complex NuRD Is Built from Preformed Catalytically Active Sub-modules Single cell studies of mouse embryonic stem cell (mESC) differentiation by electrical impedance measurements in a microfluidic device A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal MBD3 localizes at promoters, gene bodies and enhancers of active genes Promoter decommissioning by the NuRD chromatin remodeling complex triggers synaptic connectivity in the mammalian brain Sall1 balances self-renewal and differentiation of renal progenitor cells Super-enhancers in the control of cell identity and disease Comprehensive genetic analysis identifies a pathognomonic NAB2/STAT6 fusion gene, nonrandom secondary genomic imbalances, and a characteristic gene expression profile in solitary fibrous tumor.The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitment.Alternative splicing of MBD2 supports self-renewal in human pluripotent stem cells.NuRD and pluripotency: a complex balancing act.NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells.Deterministic direct reprogramming of somatic cells to pluripotency.ADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cells INO80 facilitates pluripotency gene activation in embryonic stem cell self-renewal, reprogramming, and blastocyst development.A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming.The Drosophila MI-2 chromatin-remodeling factor regulates higher-order chromatin structure and cohesin dynamics in vivo.Chromatin modifiers and remodellers: regulators of cellular differentiation Systematic discovery of Xist RNA binding proteins Global and stage specific patterns of Krüppel-associated-box zinc finger protein gene expression in murine early embryonic cells Embryonic stem cell differentiation requires full length Chd1 Dissecting the behavior and function of MBD3 in DNA methylation homeostasis by single-molecule spectroscopy and microscopy.The IKAROS interaction with a complex including chromatin remodeling and transcription elongation activities is required for hematopoiesis.The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex.Establishing pluripotency in early development.PHF6 Degrees of Separation: The Multifaceted Roles of a Chromatin Adaptor Protein.

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NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.

http://www.wikidata.org/entity/Q36108861

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NuRD suppresses pluripotency g ...... eneity and lineage commitment.

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NuRD suppresses pluripotency g ...... eneity and lineage commitment.

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NuRD suppresses pluripotency g ...... eneity and lineage commitment.

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NuRD suppresses pluripotency g ...... eneity and lineage commitment.

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J.STEM.2012.02.020

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NuRD suppresses pluripotency g ...... eneity and lineage commitment.

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Antony Hynes-Allen

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Aoife O'Shaughnessy

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Donna Leaford

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Ita Costello

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Jason Signolet

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John Strouboulis

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Kentaro Nakagawa

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Nicola Reynolds

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Olukunbi Mosaku

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Paulina Latos

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P2860

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

Nature, nurture, or chance: stochastic gene expression and its consequences

Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

NuRD and SIN3 histone deacetylase complexes in development

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst

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