Intracellular localization of phosphatidylinositide 3-kinase and insulin receptor substrate-1 in adipocytes: potential involvement of a membrane skeleton.
about
Interaction of insulin receptor substrate-1 with the sigma3A subunit of the adaptor protein complex-3 in cultured adipocytesIdentification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ...Colocalization of insulin receptor and insulin receptor substrate-1 to caveolae in primary human adipocytes. Cholesterol depletion blocks insulin signalling for metabolic and mitogenic control53BP2S, interacting with insulin receptor substrates, modulates insulin signalingIRS1-independent defects define major nodes of insulin resistanceTurnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosisAcetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylationCrystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated ProteinsInsulin receptor substrate 1 regulation of sarco-endoplasmic reticulum calcium ATPase 3 in insulin-secreting beta-cellsIdentification of pp68 as the Tyrosine-phosphorylated Form of SYNCRIP/NSAP1. A cytoplasmic RNA-binding proteinNuclear association of tyrosine-phosphorylated Vav to phospholipase C-gamma1 and phosphoinositide 3-kinase during granulocytic differentiation of HL-60 cellsOxidative stress impairs insulin but not platelet-derived growth factor signalling in 3T3-L1 adipocytesADP-ribosylation factor 6 as a target of guanine nucleotide exchange factor GRP1Localization and insulin-regulated relocation of phosphoinositide 5-kinase PIKfyve in 3T3-L1 adipocytesAkt-2 binds to Glut4-containing vesicles and phosphorylates their component proteins in response to insulinDynamics of protein-tyrosine phosphatases in rat adipocytesMembrane localization of cyclic nucleotide phosphodiesterase 3 (PDE3). Two N-terminal domains are required for the efficient targeting to, and association of, PDE3 with endoplasmic reticulumDiversification of cardiac insulin signaling involves the p85 alpha/beta subunits of phosphatidylinositol 3-kinase.GLUT4--at the cross roads between membrane trafficking and signal transduction.Spatial compartmentalization of signal transduction in insulin action.The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathwayProtein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistanceRegulation of glucose transporter 4 translocation by the Rab guanosine triphosphatase-activating protein AS160/TBC1D4: role of phosphorylation and membrane association.Regulation of brown fat adipogenesis by protein tyrosine phosphatase 1BExercise modulates postreceptor insulin signaling and glucose transport in muscle-specific insulin receptor knockout mice.Signaling pathways mediating insulin-stimulated glucose transport.A role for protein kinase Bbeta/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes.Characterization of insulin-responsive GLUT4 storage vesicles isolated from 3T3-L1 adipocytes.The pleckstrin homology (PH) domain-interacting protein couples the insulin receptor substrate 1 PH domain to insulin signaling pathways leading to mitogenesis and GLUT4 translocationNexilin, a cardiomyopathy-associated F-actin binding protein, binds and regulates IRS1 signaling in skeletal muscle cells.Intracellular segregation of phosphatidylinositol-3,4,5-trisphosphate by insulin-dependent actin remodeling in L6 skeletal muscle cellsVascular smooth muscle insulin resistance, but not hypertrophic signaling, is independent of angiotensin II-induced IRS-1 phosphorylation by JNKAn essential role of phosphatidylinositol 3-kinase in myogenic differentiation.Differential Expression of IRS-1 and IRS-2 in Uterine Leiomyosarcomas with Distinct Oncogenic Phenotypes: Lack of Correlation with Downstream Signaling Events.Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit.Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.A novel regulation of IRS1 (insulin receptor substrate-1) expression following short term insulin administration.The AP-1 complex regulates intracellular localization of insulin receptor substrate 1, which is required for insulin-like growth factor I-dependent cell proliferation.Pleckstrin homology and phosphotyrosine-binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells.
P2860
Q22004172-F60EBFEA-2F54-4377-8271-9763AFECA767Q24292896-741A3F47-0275-4682-8E19-044D6C7BCEB4Q24295215-BED19C09-BCED-4D03-B579-4FD353B229F7Q24298847-8AD66BCD-82BF-4527-AB1E-6B0A762CE930Q24647774-ECEC85E6-AEC9-465B-ADAD-B6FA941D680DQ24670558-BEF7E46E-71DF-4E77-94F8-F02928E3711BQ24797546-CC8525AC-51C8-45D1-AA88-62907E2943D5Q27619068-F4D809BF-6389-420A-A15C-5D2CC6533234Q28088661-5D2F7AA5-DE1F-4F77-996E-FB06C3C24E03Q28202752-302A1E84-92ED-4D3B-897E-1AA6BDE0B01FQ28216735-04842CC1-44A5-45AD-8D24-7D9A931BD917Q28294190-313E6C61-C5DB-43DA-97FC-98ADE6284352Q28363257-EA50E8C7-796B-4E3B-AA60-4FE45CF6F4C6Q28372643-C8C2D3EC-A373-4260-A724-4B373DB23613Q28511012-729E6C94-690F-4508-AD13-CC45BFE04C18Q28568090-0658FA5C-5777-414D-BD08-1B6C7FA6E974Q28568792-5C33DAFA-A9B8-4E27-BDFE-D336F2C39F65Q28594129-CC473A95-70FA-44A5-A4A8-5A1B7BAF44EAQ31712047-62C55EF9-2671-4C72-999E-D5004A3FB18DQ32029923-3AFC9AA4-AF8F-4433-8E7E-3D493F520133Q32063485-95036B08-8483-4B52-8203-D3D423EE4732Q33564954-3CD29B58-547C-498C-BFA4-146D451EB5AAQ33588931-1AE3E70D-1B0A-4929-92C4-450EAB6F529FQ33642606-9A45E5FE-5C16-44EB-BA6E-E10E3B4A2171Q33815738-A68A2E2B-ADBF-408A-8B20-B8E6850D0E15Q33901993-957B77E7-144D-4422-9830-BBB5D98AD2FDQ33936999-A913A767-BE1E-4799-B68F-7668108E9C3BQ33960388-AA4B7511-4ED4-42D8-A179-0DC087CCC15AQ33961335-06436A41-A848-4B01-B5D6-ECAD179873E7Q34442455-273D21DD-9795-46DE-BE2D-7580654940EAQ34576839-8E27440A-6791-4B31-979F-D182CF1A8C54Q35150570-07764550-6430-4E28-A98C-057A16D12B6AQ35601355-F5CDD961-4116-4A1C-BEC3-A6A96538AE64Q36730708-BE41BD2C-1C7F-46ED-A1E9-A2D2FE5A278FQ38613106-6DE20969-5AD8-46ED-A74A-0EBC8BB4F496Q39456427-4E5893C2-2D3B-489D-986F-FFAA82028992Q39460457-B1FD5FA1-E746-49A5-A68C-2940EDA770E2Q40380384-A8939A21-7848-44B1-8B0D-169122EC4435Q40521731-478A9048-02C1-44F5-9B15-9141E07BF5B3Q40590044-321A9CA7-AEAF-4F47-8345-2AE0291D090A
P2860
Intracellular localization of phosphatidylinositide 3-kinase and insulin receptor substrate-1 in adipocytes: potential involvement of a membrane skeleton.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Intracellular localization of ...... vement of a membrane skeleton.
@ast
Intracellular localization of ...... vement of a membrane skeleton.
@en
type
label
Intracellular localization of ...... vement of a membrane skeleton.
@ast
Intracellular localization of ...... vement of a membrane skeleton.
@en
prefLabel
Intracellular localization of ...... vement of a membrane skeleton.
@ast
Intracellular localization of ...... vement of a membrane skeleton.
@en
P2093
P2860
P356
P1476
Intracellular localization of ...... vement of a membrane skeleton.
@en
P2093
P2860
P304
P356
10.1083/JCB.140.5.1211
P407
P50
P577
1998-03-01T00:00:00Z