Amplified expression profiling of platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell disease. - Wikidata - wikimedia - TriplyDB

Amplified expression profiling of platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell disease.

Amplified expression profiling of platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell disease.

http://www.wikidata.org/entity/Q36428347

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Gene Expression Signatures of Coronary Heart Disease VAMP8/endobrevin is overexpressed in hyperreactive human platelets: suggested role for platelet microRNA Arginase induction and activation during ischemia and reperfusion and functional consequences for the heart Parallel clustering algorithm for large-scale biological data sets Morphological and functional platelet abnormalities in Berkeley sickle cell mice.Identification of a novel SBF2 missense mutation associated with a rare case of thrombocytopenia using whole-exome sequencing.A tour through the transcriptional landscape of platelets.A systematic comparison and evaluation of high density exon arrays and RNA-seq technology used to unravel the peripheral blood transcriptome of sickle cell disease.Protein kinase C ε expression in platelets from patients with acute myocardial infarction.Expression of regulatory platelet microRNAs in patients with sickle cell disease The proteome of sickle cell disease: insights from exploratory proteomic profiling.The septic milieu triggers expression of spliced tissue factor mRNA in human platelets.Newer aspects of the pathophysiology of sickle cell disease vaso-occlusion.Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum Megakaryocytes differentially sort mRNAs for matrix metalloproteinases and their inhibitors into platelets: a mechanism for regulating synthetic events.Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes.Nitric oxide and arginine dysregulation: a novel pathway to pulmonary hypertension in hemolytic disorders Gene expression analysis of whole blood, peripheral blood mononuclear cells, and lymphoblastoid cell lines from the Framingham Heart Study.Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies.RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics.Platelet mRNA: the meaning behind the message Platelets in lung biology.Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction.Sepsis alters the megakaryocyte-platelet transcriptional axis resulting in granzyme B-mediated lymphotoxicity."Message in the platelet"--more than just vestigial mRNA!Genomic architecture of sickle cell disease in West African children.Platelets in pulmonary hypertension: a causative role or a simple association?New paradigms in thrombosis: novel mediators and biomarkers platelet RNA transfer Regulation of the genetic code in megakaryocytes and platelets.Emerging roles for RNA-binding proteins as effectors and regulators of cardiovascular disease.Association of circulating transcriptomic profiles with mortality in sickle cell disease.Platelet RNA as a circulating biomarker trove for cancer diagnostics.Platelet RNA signatures for the detection of cancer.New molecular insights into modulation of platelet reactivity in aspirin-treated patients using a network-based approach.Platelet transcriptome and cardiovascular disease.Arginase Inhibition Reverses Endothelial Dysfunction, Pulmonary Hypertension, and Vascular Stiffness in Transgenic Sickle Cell Mice Hemolysis-associated hypercoagulability in sickle cell disease: the plot (and blood) thickens!Transcriptomic profiling of platelet senescence and platelet extracellular vesicles.Impact of atrial fibrillation on platelet gene expression.

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P2860

Amplified expression profiling of platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell disease.

http://www.wikidata.org/entity/Q36428347

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Amplified expression profiling ...... ents with sickle cell disease.

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Amplified expression profiling ...... ents with sickle cell disease.

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Anthony F Suffredini

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Carolea Logun

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Jennifer Barb

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Jose Villagra

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P2860

Arginine metabolism: nitric oxide and beyond

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

DAVID: Database for Annotation, Visualization, and Integrated Discovery

Polyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizyme

Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events

Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells

DNA technology, the clinical laboratory, and the future.

Nitric oxide insufficiency, platelet activation, and arterial thrombosis.

Platelets: signaling cells in the immune continuum.

The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease.

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1551-1562

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Gregory J. Kato

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sickle-cell disease

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