Re-assessing the relationship between cholesterol, statins and Alzheimer's disease.
about
Simvastatin is associated with a reduced incidence of dementia and Parkinson's diseaseStatins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretionEnrichment of cholesterol in microdissected Alzheimer's disease senile plaques as assessed by mass spectrometry.A non-invasive, rapid method to genotype late-onset Alzheimer's disease-related apolipoprotein E gene polymorphismsSemisynthesis of novel monacolin J derivatives: hypocholesterolemic and neuroprotective activities.The vascular contribution to Alzheimer's disease.Linking cardiometabolic disorders to sporadic Alzheimer's disease: a perspective on potential mechanisms and mediators.Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits.Isoprenoids and related pharmacological interventions: potential application in Alzheimer's disease.Combined treatment of Aβ immunization with statin in a mouse model of Alzheimer's disease.Amyloid beta (Aβ) peptide modulators and other current treatment strategies for Alzheimer's disease (AD).Statins and therapy of Alzheimer's disease: questions of efficacy versus trial designStatin Therapy and the Development of Cerebral Amyloid Angiopathy--A Rodent in Vivo Approach.Interventions for heart disease and their effects on Alzheimer's disease.Dyslipidemia and the risk of Alzheimer's disease.Intracerebral propagation of Alzheimer's disease: strengthening evidence of a herpes simplex virus etiologyCan statins put the brakes on Alzheimer's disease?Mechanisms of disease: new therapeutic strategies for Alzheimer's disease--targeting APP processing in lipid rafts.Simvastatin: two decades in a circle.Effects of cardiovascular medications on rate of functional decline in Alzheimer disease.Current concepts in Alzheimer's disease: a multidisciplinary review.Modifiable Midlife Risk Factors for Late-Life Cognitive Impairment and Dementia.Oxysterols in biological systems: the gastrointestinal tract, liver, vascular wall and central nervous system.Combination treatments in Alzheimer's disease: risks and benefits.Systemic and central immunity in Alzheimer's disease: therapeutic implications.Pharmacological modulation of dietary lipid-induced cerebral capillary dysfunction: Considerations for reducing risk for Alzheimer's disease.Cholesterol, 24-Hydroxycholesterol, and 27-Hydroxycholesterol as Surrogate Biomarkers in Cerebrospinal Fluid in Mild Cognitive Impairment and Alzheimer's Disease: A Meta-Analysis.Simvastatin inhibits protein isoprenylation in the brain.The beneficial effects of HMG-CoA reductase inhibitors in the processes of neurodegeneration.Cardiovascular dementia - a different perspective.High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice.Increased membrane cholesterol might render mature hippocampal neurons more susceptible to beta-amyloid-induced calpain activation and tau toxicity.Alpha-Secretase ADAM10 Regulation: Insights into Alzheimer's Disease Treatment.Preconditioning with pitavastatin, an HMG-CoA reductase inhibitor, attenuates C-Jun N-terminal kinase activation in experimental subarachnoid hemorrhage-induced apoptosis.
P2860
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P2860
Re-assessing the relationship between cholesterol, statins and Alzheimer's disease.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Re-assessing the relationship between cholesterol, statins and Alzheimer's disease.
@ast
Re-assessing the relationship between cholesterol, statins and Alzheimer's disease.
@en
type
label
Re-assessing the relationship between cholesterol, statins and Alzheimer's disease.
@ast
Re-assessing the relationship between cholesterol, statins and Alzheimer's disease.
@en
prefLabel
Re-assessing the relationship between cholesterol, statins and Alzheimer's disease.
@ast
Re-assessing the relationship between cholesterol, statins and Alzheimer's disease.
@en
P2093
P2860
P1476
Re-assessing the relationship between cholesterol, statins and Alzheimer's disease.
@en
P2093
P2860
P356
10.1111/J.1600-0404.2006.00687.X
P577
2006-01-01T00:00:00Z