Molecular attenuation of vaccinia virus: mutant generation and animal characterization
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Correlates between host and viral transcriptional program associated with different oncolytic vaccinia virus isolates.Insertion of vaccinia virus C7L host range gene into NYVAC-B genome potentiates immune responses against HIV-1 antigensVaccinia virus-encoded ribonucleotide reductase subunits are differentially required for replication and pathogenesis.Genetically stable and fully effective smallpox vaccine strain constructed from highly attenuated vaccinia LC16m8Attenuation of vaccinia Tian Tan strain by removal of viral TC7L-TK2L and TA35R genes.The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in miceIdentification of vaccinia virus epitope-specific HLA-A*0201-restricted T cells and comparative analysis of smallpox vaccines.Comparison on virulence and immunogenicity of two recombinant vaccinia vaccines, Tian Tan and Guang9 strains, expressing the HIV-1 envelope gene.The Vaccinia virus complement control protein modulates adaptive immune responses during infectionCD4+ T cell help is dispensable for protective CD8+ T cell memory against mousepox virus following vaccinia virus immunization.Deletion of major nonessential genomic regions in the vaccinia virus Lister strain enhances attenuation without altering vaccine efficacy in mice.Skin mast cells protect mice against vaccinia virus by triggering mast cell receptor S1PR2 and releasing antimicrobial peptides.Pathogeneses of respiratory infections with virulent and attenuated vaccinia viruses.The vaccinia virus A56 protein: a multifunctional transmembrane glycoprotein that anchors two secreted viral proteinsCD4(+) T-cell dependence of primary CD8(+) T-cell response against vaccinia virus depends upon route of infection and viral dose.Attenuation of Vaccinia VirusThe adenovirus E3 14.7-kilodalton protein which inhibits cytolysis by tumor necrosis factor increases the virulence of vaccinia virus in a murine pneumonia model.Deletion of the vaccinia virus B5R gene encoding a 42-kilodalton membrane glycoprotein inhibits extracellular virus envelope formation and dissemination.Vaccinia virus encodes I5, a small hydrophobic virion membrane protein that enhances replication and virulence in mice.Effects of vaccinia virus uracil DNA glycosylase catalytic site and deoxyuridine triphosphatase deletion mutations individually and together on replication in active and quiescent cells and pathogenesis in mice.Expression of the A56 and K2 proteins is sufficient to inhibit vaccinia virus entry and cell fusion.Genetically engineered poxviruses for recombinant gene expression, vaccination, and safetyNonreplicating vaccinia vector efficiently expresses recombinant genes.Vaccinia virus vaccines: past, present and future.Vaccinia virus A35R inhibits MHC class II antigen presentation.Biology of attenuated modified vaccinia virus Ankara recombinant vector in mice: virus fate and activation of B- and T-cell immune responses in comparison with the Western Reserve strain and advantages as a vaccine.Targeting Nucleotide Biosynthesis: A Strategy for Improving the Oncolytic Potential of DNA Viruses.Protection of bats (Eptesicus fuscus) against rabies following topical or oronasal exposure to a recombinant raccoon poxvirus vaccine.
P2860
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P2860
Molecular attenuation of vaccinia virus: mutant generation and animal characterization
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Molecular attenuation of vaccinia virus: mutant generation and animal characterization
@ast
Molecular attenuation of vaccinia virus: mutant generation and animal characterization
@en
type
label
Molecular attenuation of vaccinia virus: mutant generation and animal characterization
@ast
Molecular attenuation of vaccinia virus: mutant generation and animal characterization
@en
prefLabel
Molecular attenuation of vaccinia virus: mutant generation and animal characterization
@ast
Molecular attenuation of vaccinia virus: mutant generation and animal characterization
@en
P2093
P2860
P1433
P1476
Molecular attenuation of vaccinia virus: mutant generation and animal characterization
@en
P2093
B E Roberts
L C McGuigan
P2860
P304
P407
P577
1992-05-01T00:00:00Z