Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects.
about
Levofloxacin can be used effectively as a positive control in thorough QT/QTc studies in healthy volunteersUpdate on the evaluation of a new drug for effects on cardiac repolarization in humans: issues in early drug developmentQTc prolongation by psychotropic drugs and the risk of Torsade de PointesSingle Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval--A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay SensitivityVentricular dysrhythmias associated with poisoning and drug overdose: a 10-year review of statewide poison control center data from California.The thorough QT/QTc study 4 years after the implementation of the ICH E14 guidance.Drug-induced QT interval shortening: potential harbinger of proarrhythmia and regulatory perspectives.QT Interval Shortening With Isavuconazole: In Vitro and In Vivo Effects on Cardiac RepolarizationThorough QT study of the effect of oral moxifloxacin on QTc interval in the fed and fasted state in healthy Japanese and Caucasian subjectsEffect of ponesimod, a selective S1P1 receptor modulator, on the QT interval in healthy individuals.Effects of Subcutaneous Pasireotide on Cardiac Repolarization in Healthy Volunteers: a Single‐Center, Phase I, Randomized, Four‐Way Crossover StudyExplaining the unexplained; expecting the unexpected: where are we with sudden unexpected death in epilepsy?Cardiac safety, drug-induced QT prolongation and torsade de pointes (TdP).QT prolongation and torsades de pointes with psychotropic agentsDrug-induced QT-interval shortening following antiepileptic treatment with oral rufinamide.Insulin at normal physiological levels does not prolong QT(c) interval in thorough QT studies performed in healthy volunteersRepeated supratherapeutic dosing of strontium ranelate over 15 days does not prolong QT(c) interval in healthy volunteers.Choice of an alternative lead for QT interval measurement in serial ECGs when Lead II is not suitable for analysis.Epileptic Patients are at Risk of Cardiac Arrhythmias: A Novel Approach using QT-nomogram, Tachogram, and Cardiac Restitution Plots.Application of a systems pharmacology model for translational prediction of hERG-mediated QTc prolongation.The long-term safety of antiepileptic drugs.Risk of arrhythmia induced by psychotropic medications: a proposal for clinical management.Drug-Induced QT/QTc Interval Shortening: Lessons from Drug-Induced QT/QTc Prolongation.Orally administered moxifloxacin prolongs QTc in healthy Chinese volunteers: a randomized, single-blind, crossover study.Effect of Vortioxetine on Cardiac Repolarization in Healthy Adult Male Subjects: Results of a Thorough QT/QTc Study.Novel targets and regulatory ordeal by QT interval.Ventricular tachycardia associated with lacosamide co-medication in drug-resistant epilepsyDrug-induced long QT syndrome and drug development.Effect of lamotrigine on the PR interval in healthy subjects.Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects, Dixon et al. 2008; request for publication of PR interval data.Shortening of the QT interval after food can be used to demonstrate assay sensitivity in thorough QT studies.Risk of cardiac events in Long QT syndrome patients when taking antiseizure medications.Bupivacaine extended release liposome injection does not prolong QTc interval in a thorough QT/QTc study in healthy volunteers.QT/QTc study conducted in Japanese adult healthy subjects: a novel xanthine oxidase inhibitor topiroxostat was not associated with QT prolongation.Pain medication and long QT syndrome.Action Potential Recording and Pro-arrhythmia Risk Analysis in Human Ventricular Trabeculae.Increased risk of sudden unexpected death in epilepsy in females using lamotrigine: a nested, case-control study.Assessing the probability of drug-induced QTc-interval prolongation during clinical drug development.
P2860
Q24607103-6149597B-99DF-44AF-BF7A-7F0E9DB938B7Q24646866-C3452DC6-6A26-448F-A143-146DDEB58DDAQ27015763-DCE15C77-0274-4A87-961B-A210DF4B88E0Q28547388-1E4D01AC-30A6-4B22-9AC3-748746EFC884Q30883223-B5B806FE-B5C2-4CB1-A7E2-0EDB682DC7EAQ33661017-E022E8C3-57D8-4AA4-A801-D50D2196C7A6Q33661027-375481FF-5953-48CD-A301-DD76E505316BQ33837720-CD453CBF-B1EF-4ACA-BBEE-570150C481BFQ34347165-206FDEE9-E47D-4E6B-A75D-3FD89408EC3FQ34442025-DCBCE99C-3985-488F-B7D8-E40748388128Q34745395-E436972A-7A16-44C4-88F2-D36BCF14BF40Q35052178-FFF77238-9882-45C7-A857-AA6E6BC0AF9CQ36017350-03E88A5B-8F74-4D57-8596-FA45ABC53717Q36216816-7563017C-0872-4F98-82AA-B6998A92F926Q36351042-0E3D6D4D-E278-45E8-92A7-97B947C3858FQ36629217-B82957EB-16E7-479A-B6BA-98FA683B453DQ36779127-B304A412-2D89-4311-AC82-58E446E4A33CQ37388101-EA783129-42D4-4794-A64F-5C4252A66AA1Q37579328-FFE941DE-22FE-4C0F-8FB8-A651AA737EAFQ37579944-2CD35A8D-8FF3-43BD-9EA1-A0A1CF1BD25FQ38106856-123091D7-503C-44EF-A953-294492C64C63Q38197159-56A68CB0-C6BE-4648-AF6F-E9EB9B3F8EEFQ38770432-789ABE4C-F806-429F-93F6-E8E0A66D91A2Q39304680-29C8981F-4858-4DB7-84D1-6FD62B021889Q39816066-F723699B-4896-4E8A-8625-F3B656135A93Q39871284-2406C837-14FB-4EF8-86CD-A8BB9B1FAF7EQ41422969-1CA0566E-5CDF-467D-A377-DD3F467BE64EQ42419522-B7AC4190-EA5F-459E-9064-39AF92B3EBB8Q42737330-96C4A7FF-24C2-4D87-8067-51F1D796FE61Q42737335-3AA8C126-4A50-480E-AE54-451BB86D5AB8Q44134128-EA7A6227-E21F-46E7-A989-24E30E74DA0EQ47584744-0D9DCDA0-82C2-4AF8-82C0-3EBFB3C99573Q48216586-1B68DEC1-BDA8-4CFB-ACA3-582DDCAECC72Q48915041-68E267D4-564C-4487-A38B-BB2F52F8AA35Q49422188-41E33322-3523-48DD-98B6-39DE7D619ADFQ49472447-D2B661A9-B9B5-415A-B978-EA3C77FC6912Q51382080-A63D9738-D877-4471-8B22-0C6C9742FB9AQ51505796-5915E1DC-FAFF-45E3-BAE8-8EBEEE4D1901
P2860
Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects.
@en
type
label
Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects.
@en
prefLabel
Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects.
@en
P2093
P2860
P1476
Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects
@en
P2093
Debra Tompson
John G Wright
Kay Maltby
Ruth Dixon
Ruth Oliver
Ulrike Lorch
P2860
P304
P356
10.1111/J.1365-2125.2008.03250.X
P407
P50
P577
2008-07-23T00:00:00Z