Deletion of the vaccinia virus growth factor gene reduces virus virulence
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When two is better than one: thoughts on three decades of interaction between Virology and the Journal of VirologyPoxvirus pathogenesisUse of Reporter Genes in the Generation of Vaccinia Virus-Derived VectorsOncolytic virotherapy for pediatric malignancies: future prospectsExpression and cellular immunogenicity of a transgenic antigen driven by endogenous poxviral early promoters at their authentic loci in MVAAntiangiogenic arming of an oncolytic vaccinia virus enhances antitumor efficacy in renal cell cancer models.Targeting a mimotope vaccine to activating Fcgamma receptors empowers dendritic cells to prime specific CD8+ T cell responses in tumor-bearing mice.Envelope formation is blocked by mutation of a sequence related to the HKD phospholipid metabolism motif in the vaccinia virus F13L proteinAntiviral chemotherapy facilitates control of poxvirus infections through inhibition of cellular signal transduction.Host-based antipoxvirus therapeutic strategies: turning the tablesOncolytic virotherapy: molecular targets in tumor-selective replication and carrier cell-mediated delivery of oncolytic virusesSteroid hormone synthesis by a vaccinia enzyme: a new type of virus virulence factorVaccinia virus vectors: new strategies for producing recombinant vaccines.Molluscum contagiosum virus interleukin-18 (IL-18) binding protein is secreted as a full-length form that binds cell surface glycosaminoglycans through the C-terminal tail and a furin-cleaved form with only the IL-18 binding domainRedundancy complicates the definition of essential genes for vaccinia virus.Apoptin enhances the oncolytic properties of vaccinia virus and modifies mechanisms of tumor regression.Oncolytic Poxviruses.Replication efficiency of oncolytic vaccinia virus in cell cultures prognosticates the virulence and antitumor efficacy in mice.IL-18 binding and inhibition of interferon gamma induction by human poxvirus-encoded proteins.The vaccinia virus O1 protein is required for sustained activation of extracellular signal-regulated kinase 1/2 and promotes viral virulence.Isolation of a monoclonal antibody which blocks vaccinia virus infection.Chromosome mapping of Rmp-4, a gonad-dependent gene encoding host resistance to mousepox.The a sequence is dispensable for isomerization of the herpes simplex virus type 1 genome.Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963Vaccinia virus entry, exit, and interaction with differentiated human airway epithelia.Poxvirus-induced alteration of arachidonate metabolism.Multigenic evasion of inflammation by poxvirusesDeletion of the vaccinia virus B5R gene encoding a 42-kilodalton membrane glycoprotein inhibits extracellular virus envelope formation and dissemination.Insertional inactivation of the vaccinia virus 32-kilodalton gene is associated with attenuation in mice and reduction of viral gene expression in polarized epithelial cells.Evidence for intracellular down-regulation of the epidermal growth factor (EGF) receptor during adenovirus infection by an EGF-independent mechanism.Safety and biodistribution of a double-deleted oncolytic vaccinia virus encoding CD40 ligand in laboratory BeaglesThe tanapoxvirus 15L protein is a virus-encoded neuregulin that promotes viral replication in human endothelial cells.The 10,400- and 14,500-dalton proteins encoded by region E3 of adenovirus form a complex and function together to down-regulate the epidermal growth factor receptor.Molecular attenuation of vaccinia virus: mutant generation and animal characterizationDeletion analysis of two tandemly arranged virulence genes in myxoma virus, M11L and myxoma growth factorTargeting CXCL12/CXCR4 signaling with oncolytic virotherapy disrupts tumor vasculature and inhibits breast cancer metastasesUtilization of DNA recombination for the two-step replacement of growth factor sequences in the vaccinia virus genome.Host range restricted, non-replicating vaccinia virus vectors as vaccine candidates.SOCS-1 mimetics protect mice against lethal poxvirus infection: identification of a novel endogenous antiviral system.Expression of DAI by an oncolytic vaccinia virus boosts the immunogenicity of the virus and enhances antitumor immunity
P2860
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P2860
Deletion of the vaccinia virus growth factor gene reduces virus virulence
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Deletion of the vaccinia virus growth factor gene reduces virus virulence
@en
type
label
Deletion of the vaccinia virus growth factor gene reduces virus virulence
@en
prefLabel
Deletion of the vaccinia virus growth factor gene reduces virus virulence
@en
P2093
P2860
P1433
P1476
Deletion of the vaccinia virus growth factor gene reduces virus virulence
@en
P2093
D R Twardzik
J A Cooper
R M Buller
S Chakrabarti
P2860
P304
P407
P577
1988-03-01T00:00:00Z